Apoptosis-Related Gene Expression Profiling in Hematopoietic Cell Fractions of MDS Patients
Langemeijer, Saskia Mc, Mariani, Niccolo, Knops, Ruth, Gilissen, Christian, Woestenenk, Rob, de Witte, Theo, Huls, Gerwin, van der Reijden, Bert A, Jansen, Joop H
Published in PloS one (30.11.2016)
Published in PloS one (30.11.2016)
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Efficacy of Parallel and Crossover Analysis As Well As Pharmacokinetic Similarity Were Confirmed between ABP 959 and Eculizumab Reference Product in Patients with PNH
Kulasekararaj, Austin, Lanza, Francesco, Arvanitakis, Alexandros, Langemeijer, Saskia MC, Chonat, Satheesh, Cao, Jia, Chow, Vincent, Henary, Haby
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, Has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia: Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study
Peffault de Latour, Regis, Roeth, Alexander, Kulasekararaj, Austin, Scheinberg, Phillip, Ueda, Yasutaka, de Castro, Carlos M, Di Bona, Eros, Schrezenmeier, Hubert, Langemeijer, Saskia MC, Barcellini, Wilma, Tavitian, Suzanne, Panse, Jens, Schafhausen, Philippe, Mauad, Vitor AQ, Kerloeguen, Cecile, Levitch, Rafael, Kumar, Rakesh, Thorburn, Christine, Maitra, Samopriyo, Dahlke, Marion, Risitano, Antonio M
Published in Blood (06.12.2022)
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Published in Blood (06.12.2022)
Journal Article
Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, Has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia: Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study
Peffault de Latour, Regis, Roeth, Alexander, Kulasekararaj, Austin, Scheinberg, Phillip, Ueda, Yasutaka, de Castro, Carlos M, Di Bona, Eros, Schrezenmeier, Hubert, Langemeijer, Saskia MC, Barcellini, Wilma, Tavitian, Suzanne, Panse, Jens, Schafhausen, Philippe, Mauad, Vitor AQ, Kerloeguen, Cecile, Levitch, Rafael, Kumar, Rakesh, Thorburn, Christine, Maitra, Samopriyo, Dahlke, Marion, Risitano, Antonio M
Published in Blood (06.12.2022)
Published in Blood (06.12.2022)
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Journal Article
Factor B Inhibition with Oral Iptacopan Monotherapy Demonstrates Sustained Long-Term Efficacy and Safety in Anti-C5-Treated Patients (pts) with Paroxysmal Nocturnal Hemoglobinuria (PNH) and Persistent Anemia: Final 48-Week Results from the Multicenter, Phase III APPLY-PNH Trial
Risitano, Antonio M, Kulasekararaj, Austin, Roeth, Alexander, Scheinberg, Phillip, Ueda, Yasutaka, de Castro, Carlos, Di Bona, Eros, Griffin, Morag, Langemeijer, Saskia MC, Schrezenmeier, Hubert, Barcellini, Wilma, Mauad, Vitor AQ, Panse, Jens, Schafhausen, Philippe, Tavitian, Suzanne, Beggiato, Eloise, Gaya, Anna, Huang, Wei-Han, Kitawaki, Toshio, Kutlar, Abdullah, Maciejewski, Jaroslaw P., Notaro, Rosario, Pullarkat, Vinod, Schubert, Jörg, Terriou, Louis, Uchiyama, Michihiro, Sicre De Fontbrune, Flore, Frieri, Camilla, Alashkar, Ferras, Gandhi, Shreyans, Kumar, Rakesh, Thorburn, Christine, Maitra, Samopriyo, Solar-Yohay, Susan, Lawniczek, Tomasz, Dahlke, Marion, Peffault De Latour, Régis
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Somatic Mutations and DNA Hypermethylation at Enhancers and Promoters Identify Distinct Subtypes within Lower-Risk Myelodysplastic Syndromes
Rombaut, David, Tekath, Tobias, Sandmann, Sarah, Crouch, Simon, de Graaf, Aniek O., Kosmider, Olivier, Tobiasson, Magnus, Lennartsson, Andreas, Van der Reijden, Bert A., Park, Sophie, D'Aveni, Maud, Slama, Bohrane, Clappier, Emmanuelle, Fenaux, Pierre, Ades, Lionel, van de Loosdrecht, Arjan A., Langemeijer, Saskia MC, Symeonidis, Argiris S., Čermák, Jaroslav, Preudhomme, Claude, Savic, Aleksandar, Germing, Ulrich, Stauder, Reinhard, Bowen, David T., Van Marrewijk, Corine J., Bernard, Elsa, Smith, Alexandra, Painter, Daniel, de Witte, Theo J.M., Hellstrom Lindberg, Eva, Varghese, Julian, Dugas, Martin, Martens, Joost H.A., Malcovati, Luca, Jansen, Joop H., Fontenay, Michaela
Published in BLOOD (02.11.2023)
Published in BLOOD (02.11.2023)
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Conference Proceeding
MDS-273 Oral Iptacopan Monotherapy Increases Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size Via Control of Intra- and Extravascular Hemolysis in Anti-C5-Treated PNH Patients With Anemia
Risitano, Antonio M., Röth, Alexander, Kulasekararaj, Austin, Scheinberg, Phillip, Ueda, Yasutaka, de Castro, Carlos, Di Bona, Eros, Griffin, Morag, Langemeijer, Saskia MC, Schrezenmeier, Hubert, Barcellini, Wilma, Mauad, Vitor AQ, Panse, Jens, Schafhausen, Philippe, Tavitian, Suzanne, Beggiato, Eloise, Gaya, Anna, Huang, Wei-Han, Kitawaki, Toshio, Kutlar, Abdullah, Maciejewski, Jaroslaw, Notaro, Rosario, Pullarkat, Vinod, Schubert, Jörg, Terriou, Louis, Uchiyama, Michihiro, de Fontbrune, Flore Sicre, Marano, Luana, Alashkar, Ferras, Gandhi, Shreyans, Kerloeguen, Cécile, Kumar, Rakesh, Thorburn, Christine, Maitra, Samopriyo, Dahlke, Marion, de Latour, Régis Peffault
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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Journal Article
POSTER: MDS-273 Oral Iptacopan Monotherapy Increases Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size Via Control of Intra- and Extravascular Hemolysis in Anti-C5-Treated PNH Patients With Anemia
Risitano, Antonio M., Röth, Alexander, Kulasekararaj, Austin, Scheinberg, Phillip, Ueda, Yasutaka, de Castro, Carlos, Di Bona, Eros, Griffin, Morag, Langemeijer, Saskia MC, Schrezenmeier, Hubert, Barcellini, Wilma, Mauad, Vitor AQ, Panse, Jens, Schafhausen, Philippe, Tavitian, Suzanne, Beggiato, Eloise, Gaya, Anna, Huang, Wei-Han, Kitawaki, Toshio, Kutlar, Abdullah, Maciejewski, Jaroslaw, Notaro, Rosario, Pullarkat, Vinod, Schubert, Jörg, Terriou, Louis, Uchiyama, Michihiro, de Fontbrune, Flore Sicre, Marano, Luana, Alashkar, Ferras, Gandhi, Shreyans, Kerloeguen, Cécile, Kumar, Rakesh, Thorburn, Christine, Maitra, Samopriyo, Dahlke, Marion, de Latour, Régis Peffault
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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