Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
Jansen, Joop H, Nikoloski, Gorica, Langemeijer, Saskia M C, Kuiper, Roland P, Knops, Ruth, Massop, Marion, Tönnissen, Evelyn R L T M, van der Heijden, Adrian, Scheele, Theresia N, Vandenberghe, Peter, de Witte, Theo, van der Reijden, Bert A
Published in Nature genetics (01.08.2010)
Published in Nature genetics (01.08.2010)
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Journal Article
Acquired mutations in TET2 are common in myelodysplastic syndromes
Jansen, Joop H, Langemeijer, Saskia M C, Kuiper, Roland P, Berends, Marieke, Knops, Ruth, Aslanyan, Mariam G, Massop, Marion, Stevens-Linders, Ellen, van Hoogen, Patricia, van Kessel, Ad Geurts, Raymakers, Reinier A P, Kamping, Eveline J, Verhoef, Gregor E, Verburgh, Estelle, Hagemeijer, Anne, Vandenberghe, Peter, de Witte, Theo, van der Reijden, Bert A
Published in Nature genetics (01.07.2009)
Published in Nature genetics (01.07.2009)
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Journal Article
Patient preferences and quality of life implications of ravulizumab (every 8 weeks) and eculizumab (every 2 weeks) for the treatment of paroxysmal nocturnal hemoglobinuria
Peipert, John Devin, Kulasekararaj, Austin G., Gaya, Anna, Langemeijer, Saskia M. C., Yount, Susan, Gonzalez-Fernandez, F. Ataulfo, Ojeda Gutierrez, Emilio, Martens, Christa, Sparling, Amy, Webster, Kimberly A., Cella, David, Tomazos, Ioannis, Ogawa, Masayo, Piatek, Caroline I., Wells, Richard, Sicre de Fontbrune, Flore, Röth, Alexander, Mitchell, Lindsay, Hill, Anita, Kaiser, Karen
Published in PloS one (04.09.2020)
Published in PloS one (04.09.2020)
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Journal Article
Anti Thymocyte Globulin-Based Treatment for Acquired Bone Marrow Failure in Adults
Tjon, Jennifer M-L, Langemeijer, Saskia M C, Halkes, Constantijn J M
Published in Cells (Basel, Switzerland) (27.10.2021)
Published in Cells (Basel, Switzerland) (27.10.2021)
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Journal Article
Neutrophil specific granule and NETosis defects in gray platelet syndrome
Aarts, Cathelijn E.M., Downes, Kate, Hoogendijk, Arie J., Sprenkeler, Evelien G.G., Gazendam, Roel P., Favier, Rémi, Favier, Marie, Tool, Anton T.J., van Hamme, John L., Kostadima, Myrto A., Waller, Kate, Zieger, Barbara, van Bergen, Maaike G.J.M., Langemeijer, Saskia M.C., van der Reijden, Bert A., Janssen, Hans, van den Berg, Timo K., van Bruggen, Robin, Meijer, Alexander B., Ouwehand, Willem H., Kuijpers, Taco W.
Published in Blood advances (26.01.2021)
Published in Blood advances (26.01.2021)
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Journal Article
Clinical and biological impact of TET2 mutations and expression in younger adult AML patients treated within the EORTC/GIMEMA AML-12 clinical trial
Aslanyan, Mariam G., Kroeze, Leonie I., Langemeijer, Saskia M. C., Koorenhof-Scheele, Theresia N., Massop, Marion, van Hoogen, Patricia, Stevens-Linders, Ellen, van de Locht, Louis T., Tönnissen, Evelyn, van der Heijden, Adrian, da Silva-Coelho, Pedro, Cilloni, Daniela, Saglio, Giuseppe, Marie, Jean-Pierre, Tang, Ruoping, Labar, Boris, Amadori, Sergio, Muus, Petra, Willemze, Roel, Marijt, Erik W. A., de Witte, Theo, van der Reijden, Bert A., Suciu, Stefan, Jansen, Joop H.
Published in Annals of hematology (01.08.2014)
Published in Annals of hematology (01.08.2014)
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Journal Article
Dose optimalization of subcutaneous ravulizumab is predicted to yield significant savings and to improve patient friendliness
Avest, Mendy, Langemeijer, Saskia M. C., Blijlevens, Nicole M. A., Kar, Nicole C. A. J., Heine, Rob
Published in British journal of clinical pharmacology (01.03.2023)
Published in British journal of clinical pharmacology (01.03.2023)
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Journal Article
Development of a target concentration intervention to individualize paroxysmal nocturnal hemoglobinuria treatment with pegcetacoplan
ter Avest, Mendy, Langemeijer, Saskia M.C, Blijlevens, Nicole M.A., van de Kar, Nicole C.A.J., ter Heine, Rob
Published in Annals of hematology (01.07.2024)
Published in Annals of hematology (01.07.2024)
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Journal Article
Proteinuria and Exposure to Eculizumab in Atypical Hemolytic Uremic Syndrome
Ter Avest, Mendy, Steenbreker, Hilbert, Bouwmeester, Romy N, Duineveld, Caroline, Wijnsma, Kioa L, van den Heuvel, Lambertus P W J, Langemeijer, Saskia M C, Wetzels, Jack F M, van de Kar, Nicole C A J, Ter Heine, Rob
Published in Clinical journal of the American Society of Nephrology (01.06.2023)
Published in Clinical journal of the American Society of Nephrology (01.06.2023)
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Journal Article
Infections during eculizumab therapy in a Dutch population of patients with paroxysmal nocturnal haemoglobinuria
Schaap, Charlotte C.M., Grotens, Ayla, de Haan, Anton F.J., Blijlevens, Nicole M.A., Langemeijer, Saskia M.C.
Published in Clinical microbiology and infection (01.10.2021)
Published in Clinical microbiology and infection (01.10.2021)
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Journal Article
The potential of individualized dosing of ravulizumab to improve patient‐friendliness of paroxysmal nocturnal haemoglobinuria treatment at reduced costs
Avest, Mendy, Langemeijer, Saskia M.C., Schols, Saskia E.M., Burger, David M., Kar, Nicole C.A.J., Blijlevens, Nicole M.A., Kievit, Wietske, Heine, Rob
Published in British journal of clinical pharmacology (01.08.2021)
Published in British journal of clinical pharmacology (01.08.2021)
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Journal Article
Nationwide study of eculizumab in paroxysmal nocturnal hemoglobinuria: Evaluation of treatment indications and outcomes
Schaap, Charlotte C. M., Heubel‐Moenen, Floor C. J. I., Nur, Erfan, Bartels, Marije, Heijden, Olivier W. H., Jonge, Emiel, Preijers, Frank W. M. B., Blijlevens, Nicole M. A., Langemeijer, Saskia M. C.
Published in European journal of haematology (01.06.2023)
Published in European journal of haematology (01.06.2023)
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Journal Article
TET proteins in malignant hematopoiesis
Langemeijer, Saskia M.C., Aslanyan, Mariam G., Jansen, Joop H.
Published in Cell cycle (Georgetown, Tex.) (15.12.2009)
Published in Cell cycle (Georgetown, Tex.) (15.12.2009)
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Journal Article
Effect of Eculizumab on Iron Metabolism in Transfusion‐independent Patients With Paroxysmal Nocturnal Hemoglobinuria
Schaap, Charlotte C.M., Schols, Saskia E.M., Preijers, Frank W.M.B., Jonge, Emiel, Laarakkers, Coby M.M., Jansen, Joop H., Blijlevens, Nicole M.A., Swinkels, Dorine W., Langemeijer, Saskia M.C.
Published in HemaSphere (01.05.2023)
Published in HemaSphere (01.05.2023)
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Journal Article
Apoptosis-Related Gene Expression Profiling in Hematopoietic Cell Fractions of MDS Patients
Langemeijer, Saskia Mc, Mariani, Niccolo, Knops, Ruth, Gilissen, Christian, Woestenenk, Rob, de Witte, Theo, Huls, Gerwin, van der Reijden, Bert A, Jansen, Joop H
Published in PloS one (30.11.2016)
Published in PloS one (30.11.2016)
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Journal Article
Prospective validation of initial eculizumab dosing in adults with atypical hemolytic uremic syndrome
Ter Avest, Mendy, Duineveld, Caroline, Bouwmeester, Romy N, Baas, Laura M, van den Heuvel, Lambertus P W J, Langemeijer, Saskia M C, Wetzels, Jack F M, van de Kar, Nicole C A J, Ter Heine, Rob
Published in Nephrology, dialysis, transplantation (12.11.2024)
Published in Nephrology, dialysis, transplantation (12.11.2024)
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Journal Article
Oral Iptacopan Monotherapy in Paroxysmal Nocturnal Hemoglobinuria
Peffault de Latour, Régis, Röth, Alexander, Kulasekararaj, Austin G., Han, Bing, Scheinberg, Phillip, Maciejewski, Jaroslaw P., Ueda, Yasutaka, de Castro, Carlos M., Di Bona, Eros, Fu, Rong, Zhang, Li, Griffin, Morag, Langemeijer, Saskia M.C., Panse, Jens, Schrezenmeier, Hubert, Barcellini, Wilma, Mauad, Vitor A.Q., Schafhausen, Philippe, Tavitian, Suzanne, Beggiato, Eloise, Chew, Lee Ping, Gaya, Anna, Huang, Wei-Han, Jang, Jun Ho, Kitawaki, Toshio, Kutlar, Abdullah, Notaro, Rosario, Pullarkat, Vinod, Schubert, Jörg, Terriou, Louis, Uchiyama, Michihiro, Wong Lee Lee, Lily, Yap, Eng-Soo, Sicre de Fontbrune, Flore, Marano, Luana, Alashkar, Ferras, Gandhi, Shreyans, Trikha, Roochi, Yang, Chen, Liu, Hui, Kelly, Richard J., Höchsmann, Britta, Kerloeguen, Cécile, Banerjee, Partha, Levitch, Rafael, Kumar, Rakesh, Wang, Zhixin, Thorburn, Christine, Maitra, Samopriyo, Li, Shujie, Verles, Aurelie, Dahlke, Marion, Risitano, Antonio M.
Published in The New England journal of medicine (14.03.2024)
Published in The New England journal of medicine (14.03.2024)
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Journal Article
Validation of the Qualms Questionnaire to Assess Health-Related Quality of Life in European and Israeli Patients with Myelodysplastic Syndromes: Results from the MDS-Right Project
Efficace, Fabio, Koinig, Karin A, Cottone, Francesco, Bowen, David, Mittelman, Moshe, Langemeijer, Saskia M.C., Culligan, Dominic, Filanovsky, Kalman, Abel, Gregory A., Storck, Michael, Smith, Alexandra, Van Marrewijk, Corine, Dugas, Martin, de Witte, Theo M, Stauder, Reinhard
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Genetic Diversity within Leukemia-Associated Immunophenotype-Defined Subclones in AML
Tiso, Francesca, Koorenhof-Scheele, Thessa N., Huys, Erik, Martens, Joost H.A., De Graaf, Aniek O., van der Reijden, Bert A., Langemeijer, Saskia M.C., Preijers, Frank W. M.B., Kroeze, Leonie I., Jansen, Joop H.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Patient preferences and quality of life implications of ravulizumab
Peipert, John Devin, Kulasekararaj, Austin G, Gaya, Anna, Langemeijer, Saskia M. C, Yount, Susan, Gonzalez-Fernandez, F. Ataulfo, Ojeda Gutierrez, Emilio, Martens, Christa, Sparling, Amy, Webster, Kimberly A, Cella, David, Tomazos, Ioannis, Ogawa, Masayo, Piatek, Caroline I, Wells, Richard, Sicre de Fontbrune, Flore, Röth, Alexander, Mitchell, Lindsay, Hill, Anita, Kaiser, Karen
Published in PloS one (04.09.2020)
Published in PloS one (04.09.2020)
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Journal Article