PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors
Searcy, Madeline B., Larsen, Randolph K., Stevens, Bradley T., Zhang, Yang, Jin, Hongjian, Drummond, Catherine J., Langdon, Casey G., Gadek, Katherine E., Vuong, Kyna, Reed, Kristin B., Garcia, Matthew R., Xu, Beisi, Kimbrough, Darden W., Adkins, Grace E., Djekidel, Nadhir, Porter, Shaina N., Schreiner, Patrick A., Pruett-Miller, Shondra M., Abraham, Brian J., Rehg, Jerold E., Hatley, Mark E.
Published in Nature communications (15.11.2023)
Published in Nature communications (15.11.2023)
Get full text
Journal Article
Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity
Langdon, Casey G., Gadek, Katherine E., Garcia, Matthew R., Evans, Myron K., Reed, Kristin B., Bush, Madeline, Hanna, Jason A., Drummond, Catherine J., Maguire, Matthew C., Leavey, Patrick J., Finkelstein, David, Jin, Hongjian, Schreiner, Patrick A., Rehg, Jerold E., Hatley, Mark E.
Published in Nature communications (17.09.2021)
Published in Nature communications (17.09.2021)
Get full text
Journal Article
Genotype-selective combination therapies for melanoma identified by high-throughput drug screening
Held, Matthew A, Langdon, Casey G, Platt, James T, Graham-Steed, Tisheeka, Liu, Zongzhi, Chakraborty, Ashok, Bacchiocchi, Antonella, Koo, Andrew, Haskins, Jonathan W, Bosenberg, Marcus W, Stern, David F
Published in Cancer discovery (01.01.2013)
Published in Cancer discovery (01.01.2013)
Get full text
Journal Article
PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets
Scortegagna, Marzia, Lau, Eric, Zhang, Tongwu, Feng, Yongmei, Sereduk, Chris, Yin, Hongwei, De, Surya K, Meeth, Katrina, Platt, James T, Langdon, Casey G, Halaban, Ruth, Pellecchia, Maurizio, Davies, Michael A, Brown, Kevin, Stern, David F, Bosenberg, Marcus, Ronai, Ze'ev A
Published in Cancer research (Chicago, Ill.) (01.04.2015)
Published in Cancer research (Chicago, Ill.) (01.04.2015)
Get full text
Journal Article
Genetic context of oncogenic drivers dictates vascular sarcoma development in aP2‐Cre mice
Hanna, Jason A, Langdon, Casey G, Garcia, Matthew R, Benton, Annaleigh, Lanman, Nadia A, Finkelstein, David, Rehg, Jerold E, Hatley, Mark E
Published in The Journal of pathology (01.05.2022)
Published in The Journal of pathology (01.05.2022)
Get full text
Journal Article
p90RSK Blockade Inhibits Dual BRAF and MEK Inhibitor-Resistant Melanoma by Targeting Protein Synthesis
Theodosakis, Nicholas, Micevic, Goran, Langdon, Casey G., Ventura, Alessandra, Means, Robert, Stern, David F., Bosenberg, Marcus W.
Published in Journal of investigative dermatology (01.10.2017)
Published in Journal of investigative dermatology (01.10.2017)
Get full text
Journal Article
Systematic Drug Screening Identifies Tractable Targeted Combination Therapies in Triple-Negative Breast Cancer
Wali, Vikram B, Langdon, Casey G, Held, Matthew A, Platt, James T, Patwardhan, Gauri A, Safonov, Anton, Aktas, Bilge, Pusztai, Lajos, Stern, David F, Hatzis, Christos
Published in Cancer research (Chicago, Ill.) (15.01.2017)
Published in Cancer research (Chicago, Ill.) (15.01.2017)
Get full text
Journal Article
Inhibition of isoprenylation synergizes with MAPK blockade to prevent growth in treatment‐resistant melanoma, colorectal, and lung cancer
Theodosakis, Nicholas, Langdon, Casey G., Micevic, Goran, Krykbaeva, Irina, Means, Robert E., Stern, David F., Bosenberg, Marcus W.
Published in Pigment cell and melanoma research (01.03.2019)
Published in Pigment cell and melanoma research (01.03.2019)
Get full text
Journal Article
Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor
Langdon, Casey G, Platt, James T, Means, Robert E, Iyidogan, Pinar, Mamillapalli, Ramanaiah, Klein, Michael, Held, Matthew A, Lee, Jong Woo, Koo, Ja Seok, Hatzis, Christos, Hochster, Howard S, Stern, David F
Published in Molecular cancer therapeutics (01.06.2017)
Published in Molecular cancer therapeutics (01.06.2017)
Get full text
Journal Article
SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells
Langdon, Casey G, Wiedemann, Norbert, Held, Matthew A, Mamillapalli, Ramanaiah, Iyidogan, Pinar, Theodosakis, Nicholas, Platt, James T, Levy, Frederic, Vuagniaux, Gregoire, Wang, Shaomeng, Bosenberg, Marcus W, Stern, David F
Published in Oncotarget (10.11.2015)
Published in Oncotarget (10.11.2015)
Get full text
Journal Article
The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors
Langdon, Casey G., Held, Matthew A., Platt, James T., Meeth, Katrina, Iyidogan, Pinar, Mamillapalli, Ramanaiah, Koo, Andrew B., Klein, Michael, Liu, Zongzhi, Bosenberg, Marcus W., Stern, David F.
Published in Pigment cell and melanoma research (01.07.2015)
Published in Pigment cell and melanoma research (01.07.2015)
Get full text
Journal Article
Abstract 3022: Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma indentity
Langdon, Casey G., Gadek, Katherine E., Garcia, Matthew R., Reed, Kristin B., Bush, Madeline, Hanna, Jason A., Drummond, Catherine J., Maguire, Matthew C., Leavey, Patrick J., Finkelstein, David, Jin, Hongjian, Rehg, Jerold E., Hatley, Mark E.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
Abstract IA013: Rhabdomyosarcoma: visions through the looking glass
Hatley, Mark E., Langdon, Casey G., Gadek, Katherine E., Garcia, Matthew R., Drummond, Catherine J., Hanna, Jason A., Jin, Hongjian E., Rehg, Jerold E.
Published in Clinical cancer research (15.09.2022)
Published in Clinical cancer research (15.09.2022)
Get full text
Journal Article
Abstract 1792: Identification of synergistic drug combinations with the oral HSP90 inhibitor Debio 0932 in non-small cell lung cancer and renal cell cancer
Langdon, Casey G., Wiedemann, Norbert, Hajjami, Hélène Maby-El, Held, Mathew A., Platt, James T., Vuagniaux, Grégoire, Bosenberg, Marcus W., Stern, David F., Lévy, Frédéric
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article
Abstract 2529: Debio 1143 synergizes with taxanes, topoisomerase and bromodomain inhibitors to inhibit growth of lung adenocarcinoma
Langdon, Casey G., Wiedemann, Norbert, Held, Matthew A., Platt, James T., Mamillapalli, Ramanaiah, Iyidogan, Pinar, Theodosakis, Nicholas, Levy, Frederic, Robichon, Denis, Zanna, Claudio, Vuagniaux, Gregoire, Sorensen, Mel, Wang, Shaomeng, Bosenberg, Marcus W., Stern, David F.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Get full text
Journal Article
Abstract B275: Dovitinib as a single-agent or in combination with other small molecule inhibitors for mutant BRAF melanomas
Langdon, Casey G., Held, Matthew A., Koo, Andrew B., Klein, Michael, Liu, Zongzhi, Platt, James T., Stern, David F.
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
Get full text
Journal Article
Abstract 1667: Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity
Langdon, Casey G., Gadek, Katherine E., Garcia, Matthew R., Evans, Myron K., Reed, Kristin B., Bush, Madeline, Hanna, Jason A., Drummond, Catherine J., Maguire, Matthew C., Leavey, Patrick J., Finkelstein, David, Jin, Hongjian, Schreiner, Patrick A., Rehg, Jerold E., Hatley, Mark E.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article