Targeting Huntingtin Expression in Patients with Huntington’s Disease
Tabrizi, Sarah J, Leavitt, Blair R, Landwehrmeyer, G. Bernhard, Wild, Edward J, Saft, Carsten, Barker, Roger A, Blair, Nick F, Craufurd, David, Priller, Josef, Rickards, Hugh, Rosser, Anne, Kordasiewicz, Holly B, Czech, Christian, Swayze, Eric E, Norris, Daniel A, Baumann, Tiffany, Gerlach, Irene, Schobel, Scott A, Paz, Erika, Smith, Anne V, Bennett, C. Frank, Lane, Roger M
Published in The New England journal of medicine (13.06.2019)
Published in The New England journal of medicine (13.06.2019)
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Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
Tabrizi, Sarah J, Prof, Scahill, Rachael I, PhD, Durr, Alexandra, MD, Roos, Raymund AC, MD, Leavitt, Blair R, FRCPC, Jones, Rebecca, MSc, Landwehrmeyer, G Bernhard, MD, Fox, Nick C, MD, Johnson, Hans, PhD, Hicks, Stephen L, PhD, Kennard, Christopher, FRCP, Craufurd, David, FRCPsych, Frost, Chris, PhD, Langbehn, Douglas R, MD, Reilmann, Ralf, MD, Stout, Julie C, PhD
Published in Lancet neurology (2011)
Published in Lancet neurology (2011)
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Speech biomarkers in Huntington's disease: A cross‐sectional study in pre‐symptomatic, prodromal and early manifest stages
Kouba, Tomas, Frank, Wiebke, Tykalova, Tereza, Mühlbäck, Alzbeta, Klempíř, Jiří, Lindenberg, Katrin S., Landwehrmeyer, G. Bernhard, Rusz, Jan
Published in European journal of neurology (01.05.2023)
Published in European journal of neurology (01.05.2023)
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Journal Article
Tominersen in Adults with Manifest Huntington's Disease
McColgan, Peter, Thobhani, Alpa, Boak, Lauren, Schobel, Scott A, Nicotra, Alessia, Palermo, Giuseppe, Trundell, Dylan, Zhou, Julian, Schlegel, Valerie, Sanwald Ducray, Patricia, Hawellek, David J, Dorn, Jonas, Simillion, Cedric, Lindemann, Michael, Wheelock, Vicki, Durr, Alexandra, Anderson, Karen E, Long, Jeffrey D, Wild, Edward J, Landwehrmeyer, G Bernhard, Leavitt, Blair R, Tabrizi, Sarah J, Doody, Rachelle
Published in The New England journal of medicine (07.12.2023)
Published in The New England journal of medicine (07.12.2023)
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Exome sequencing of individuals with Huntington's disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset
McAllister, Branduff, Donaldson, Jasmine, Binda, Caroline S, Powell, Sophie, Chughtai, Uroosa, Edwards, Gareth, Stone, Joseph, Lobanov, Sergey, Elliston, Linda, Schuhmacher, Laura-Nadine, Rees, Elliott, Menzies, Georgina, Ciosi, Marc, Maxwell, Alastair, Chao, Michael J, Hong, Eun Pyo, Lucente, Diane, Wheeler, Vanessa, Lee, Jong-Min, MacDonald, Marcy E, Long, Jeffrey D, Aylward, Elizabeth H, Landwehrmeyer, G Bernhard, Rosser, Anne E, Paulsen, Jane S, Williams, Nigel M, Gusella, James F, Monckton, Darren G, Allen, Nicholas D, Holmans, Peter, Jones, Lesley, Massey, Thomas H
Published in Nature neuroscience (01.04.2022)
Published in Nature neuroscience (01.04.2022)
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Suicidal ideation and suicidal behavior according to the C-SSRS in a European cohort of Huntington's disease gene expansion carriers
van Duijn, Erik, Vrijmoeth, Eslie M., Giltay, Erik J., Bernhard Landwehrmeyer, G.
Published in Journal of affective disorders (01.03.2018)
Published in Journal of affective disorders (01.03.2018)
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Ubiquitination and the proteasome rather than caspase‐3‐mediated C‐terminal cleavage are involved in the EAAT2 degradation by staurosporine‐induced cellular stress
Voss, Timo‐Daniel, Gerget, Maria, Linkus, Birgit, Einem, Bjoern, Landwehrmeyer, G. Bernhard, Lewerenz, Jan
Published in Journal of neurochemistry (01.05.2021)
Published in Journal of neurochemistry (01.05.2021)
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Different CSF protein profiles in amyotrophic lateral sclerosis and frontotemporal dementia with C9orf72 hexanucleotide repeat expansion
Barschke, Peggy, Oeckl, Patrick, Steinacker, Petra, Al Shweiki, MHD Rami, Weishaupt, Jochen H, Landwehrmeyer, G Bernhard, Anderl-Straub, Sarah, Weydt, Patrick, Diehl-Schmid, Janine, Danek, Adrian, Kornhuber, Johannes, Schroeter, Matthias L, Prudlo, Johannes, Jahn, Holger, Fassbender, Klaus, Lauer, Martin, van der Ende, Emma Louise, van Swieten, John Cornelis, Volk, Alexander E, Ludolph, Albert C, Otto, Markus
Published in Journal of neurology, neurosurgery and psychiatry (01.05.2020)
Published in Journal of neurology, neurosurgery and psychiatry (01.05.2020)
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Journal Article
General loss of proteostasis links Huntington disease to Cockayne syndrome
Wagner, Maximilian, Zhu, Gaojie, Khalid, Fatima, Phan, Tamara, Maity, Pallab, Lupu, Ludmila, Agyeman-Duah, Eric, Wiese, Sebastian, Lindenberg, Katrin S., Schön, Michael, Landwehrmeyer, G. Bernhard, Penzo, Marianna, Kochanek, Stefan, Scharffetter-Kochanek, Karin, Mulaw, Medhanie, Iben, Sebastian
Published in Neurobiology of disease (01.10.2024)
Published in Neurobiology of disease (01.10.2024)
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Journal Article
Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues
Hoschek, Franziska, Natan, Julia, Wagner, Maximilian, Sathasivam, Kirupa, Abdelmoez, Alshaimaa, von Einem, Björn, Bates, Gillian P, Landwehrmeyer, G Bernhard, Neueder, Andreas
Published in Molecular medicine (Cambridge, Mass.) (08.03.2024)
Published in Molecular medicine (Cambridge, Mass.) (08.03.2024)
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Journal Article
Correction: Huntingtin HTT1a is generated in a CAG repeat-length-dependent manner in human tissues
Hoschek, Franziska, Natan, Julia, Wagner, Maximilian, Sathasivam, Kirupa, Abdelmoez, Alshaimaa, Einem, Björn von, Bates, Gillian P, Landwehrmeyer, G Bernhard, Neueder, Andreas
Published in Molecular medicine (Cambridge, Mass.) (10.04.2024)
Published in Molecular medicine (Cambridge, Mass.) (10.04.2024)
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Journal Article
Olfactory screening of Parkinson's Disease patients and healthy subjects in China and Germany: A study of cross-cultural adaptation of the Sniffin' Sticks 12-identification test
Pinkhardt, Elmar H, Liu, Huijing, Ma, Di, Chen, Jing, Pachollek, Adrian, Kunz, Martin S, Kassubek, Jan, Ludolph, Albert C, Huang, Yining, Chen, Haibo, Landwehrmeyer, G Bernhard, Wang, Zhaoxia, Su, Wen
Published in PloS one (08.11.2019)
Published in PloS one (08.11.2019)
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A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset
SOYAL, Selma M, FELDER, Thomas K, AUER, Simon, HAHNE, Penelope, OBERKOFLER, Hannes, WITTING, Anke, PAULMICHL, Markus, BERNHARD LANDWEHRMEYER, G, WEYDT, Patrick, PATSCH, Wolfgang
Published in Human molecular genetics (01.08.2012)
Published in Human molecular genetics (01.08.2012)
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Journal Article
HAP40 protein levels are huntingtin-dependent and decrease in Huntington disease
Huang, Bin, Seefelder, Manuel, Buck, Eva, Engler, Tatjana, Lindenberg, Katrin S., Klein, Fabrice, Landwehrmeyer, G. Bernhard, Kochanek, Stefan
Published in Neurobiology of disease (01.10.2021)
Published in Neurobiology of disease (01.10.2021)
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Journal Article
Riluzole in Huntington's disease: a 3-year, randomized controlled study
Landwehrmeyer, G. Bernhard, Dubois, Bruno, de Yébenes, Justo Garcia, Kremer, Berry, Gaus, Wilhelm, Kraus, Peter H., Przuntek, Horst, Dib, Michel, Doble, Adam, Fischer, Wilhelm, Ludolph, Albert C.
Published in Annals of neurology (01.09.2007)
Published in Annals of neurology (01.09.2007)
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Journal Article
Fast-to-Slow Transition of Skeletal Muscle Contractile Function and Corresponding Changes in Myosin Heavy and Light Chain Formation in the R6/2 Mouse Model of Huntington's Disease
Hering, Tanja, Braubach, Peter, Landwehrmeyer, G Bernhard, Lindenberg, Katrin S, Melzer, Werner
Published in PloS one (07.11.2016)
Published in PloS one (07.11.2016)
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Research priorities for rare neurological diseases: a representative view of patient representatives and healthcare professionals from the European Reference Network for Rare Neurological Diseases
Post, Annemarie E M, Klockgether, Thomas, Landwehrmeyer, G Bernhard, Pandolfo, Massimo, Arnesen, Astri, Reinhard, Carola, Graessner, Holm
Published in Orphanet journal of rare diseases (18.03.2021)
Published in Orphanet journal of rare diseases (18.03.2021)
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Journal Article
Enroll-HD: An Integrated Clinical Research Platform and Worldwide Observational Study for Huntington's Disease
Sathe, Swati, Ware, Jen, Levey, Jamie, Neacy, Eileen, Blumenstein, Robi, Noble, Simon, Mühlbäck, Alzbeta, Rosser, Anne, Landwehrmeyer, G Bernhard, Sampaio, Cristina
Published in Frontiers in neurology (18.08.2021)
Published in Frontiers in neurology (18.08.2021)
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Commentary: Acanthocytes identified in Huntington's disease
Peikert, Kevin, Storch, Alexander, Hermann, Andreas, Landwehrmeyer, G. Bernhard, Walker, Ruth H., Simionato, Greta, Kaestner, Lars, Danek, Adrian
Published in Frontiers in neuroscience (04.11.2022)
Published in Frontiers in neuroscience (04.11.2022)
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