NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment
Cantrelle, François‐Xavier, Boll, Emmanuelle, Brier, Lucile, Moschidi, Danai, Belouzard, Sandrine, Landry, Valérie, Leroux, Florence, Dewitte, Frédérique, Landrieu, Isabelle, Dubuisson, Jean, Deprez, Benoit, Charton, Julie, Hanoulle, Xavier
Published in Angewandte Chemie International Edition (22.11.2021)
Published in Angewandte Chemie International Edition (22.11.2021)
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Published in International journal of molecular sciences (12.12.2023)
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Published in European journal of medicinal chemistry (05.10.2024)
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Published in Scientific reports (18.09.2017)
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Kraupner, Nicolas, Dinh, Chau Phi, Wen, Xiaoan, Landry, Valérie, Herledan, Adrien, Leroux, Florence, Bosc, Damien, Charton, Julie, Maillard, Clara, Warenghem, Sandrine, Duplan, Isabelle, Piveteau, Catherine, Hennuyer, Nathalie, Staels, Bart, Deprez, Benoit, Deprez-Poulain, Rebecca
Published in European journal of medicinal chemistry (15.01.2022)
Published in European journal of medicinal chemistry (15.01.2022)
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Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening
Leroux, Florence, Bosc, Damien, Beghyn, Terence, Hermant, Paul, Warenghem, Sandrine, Landry, Valérie, Pottiez, Virginie, Guillaume, Valentin, Charton, Julie, Herledan, Adrien, Urata, Sarah, Liang, Wenguang, Sheng, Li, Tang, Wei-Jen, Deprez, Benoit, Deprez-Poulain, Rebecca
Published in European journal of medicinal chemistry (01.10.2019)
Published in European journal of medicinal chemistry (01.10.2019)
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Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis
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Published in Bioorganic chemistry (01.12.2018)
Published in Bioorganic chemistry (01.12.2018)
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A microscopic phenotypic assay for the quantification of intracellular mycobacteria adapted for high-throughput/high-content screening
Queval, Christophe J, Song, Ok-Ryul, Delorme, Vincent, Iantomasi, Raffaella, Veyron-Churlet, Romain, Deboosère, Nathalie, Landry, Valérie, Baulard, Alain, Brodin, Priscille
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Published in Journal of visualized experiments (17.01.2014)
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New non-hydroxamic ADAMTS-5 inhibitors based on the 1,2,4-triazole-3-thiol scaffold
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Published in Bioorganic & medicinal chemistry letters (01.11.2010)
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2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substrates of Trypanothione Reductase and Lipoamide Dehydrogenase from Trypanosoma cruzi: Synthesis and Correlation between Redox Cycling Activities and in Vitro Cytotoxicity
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Published in Journal of medicinal chemistry (15.02.2001)
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2‑Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1
Neres, João, Hartkoorn, Ruben C, Chiarelli, Laurent R, Gadupudi, Ramakrishna, Pasca, Maria Rosalia, Mori, Giorgia, Venturelli, Alberto, Savina, Svetlana, Makarov, Vadim, Kolly, Gaelle S, Molteni, Elisabetta, Binda, Claudia, Dhar, Neeraj, Ferrari, Stefania, Brodin, Priscille, Delorme, Vincent, Landry, Valérie, de Jesus Lopes Ribeiro, Ana Luisa, Farina, Davide, Saxena, Puneet, Pojer, Florence, Carta, Antonio, Luciani, Rosaria, Porta, Alessio, Zanoni, Giuseppe, De Rossi, Edda, Costi, Maria Paola, Riccardi, Giovanna, Cole, Stewart T
Published in ACS chemical biology (20.03.2015)
Published in ACS chemical biology (20.03.2015)
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The MAP kinase pathway mediates transcytosis induced by TNF-α in an in vitro blood-brain barrier model
Miller, Florence, Fenart, Laurence, Landry, Valérie, Coisne, Caroline, Cecchelli, Roméo, Dehouck, Marie-Pierre, Buée-Scherrer, Valérie
Published in The European journal of neuroscience (01.08.2005)
Published in The European journal of neuroscience (01.08.2005)
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Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice
Deprez-Poulain, Rebecca, Hennuyer, Nathalie, Bosc, Damien, Liang, Wenguang G., Enée, Emmanuelle, Marechal, Xavier, Charton, Julie, Totobenazara, Jane, Berte, Gonzague, Jahklal, Jouda, Verdelet, Tristan, Dumont, Julie, Dassonneville, Sandrine, Woitrain, Eloise, Gauriot, Marion, Paquet, Charlotte, Duplan, Isabelle, Hermant, Paul, Cantrelle, François- Xavier, Sevin, Emmanuel, Culot, Maxime, Landry, Valerie, Herledan, Adrien, Piveteau, Catherine, Lippens, Guy, Leroux, Florence, Tang, Wei-Jen, van Endert, Peter, Staels, Bart, Deprez, Benoit
Published in Nature communications (23.09.2015)
Published in Nature communications (23.09.2015)
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Structure–activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme
Charton, Julie, Gauriot, Marion, Totobenazara, Jane, Hennuyer, Nathalie, Dumont, Julie, Bosc, Damien, Marechal, Xavier, Elbakali, Jamal, Herledan, Adrien, Wen, Xiaoan, Ronco, Cyril, Gras-Masse, Helene, Heninot, Antoine, Pottiez, Virginie, Landry, Valerie, Staels, Bart, Liang, Wenguang G., Leroux, Florence, Tang, Wei-Jen, Deprez, Benoit, Deprez-Poulain, Rebecca
Published in European journal of medicinal chemistry (27.01.2015)
Published in European journal of medicinal chemistry (27.01.2015)
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NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment
Cantrelle, François‐Xavier, Boll, Emmanuelle, Brier, Lucile, Moschidi, Danai, Belouzard, Sandrine, Landry, Valérie, Leroux, Florence, Dewitte, Frédérique, Landrieu, Isabelle, Dubuisson, Jean, Deprez, Benoit, Charton, Julie, Hanoulle, Xavier
Published in Angewandte Chemie (22.11.2021)
Published in Angewandte Chemie (22.11.2021)
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A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening
Queval, Christophe. J, Song, Ok-Ryul, Delorme, Vincent, Iantomasi, Raffaella, Veyron-Churlet, Romain, Deboosère, Nathalie, Landry, Valérie, Baulard, Alain, Brodin, Priscille
Published in Journal of visualized experiments (17.01.2014)
Published in Journal of visualized experiments (17.01.2014)
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Corrigendum to “Synthesis of a 200-member library of squaric acid N-hydroxylamide amides” [Bioorg. Med. Chem. Lett. 18 (2008) 4968–4971]
Charton, Julie, Leroux, Florence, Delaroche, Sylvain, Landry, Valérie, Déprez, Benoît P., Déprez-Poulain, Rébecca F.
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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Synthesis of a 200-member library of squaric acid N-hydroxylamide amides
Charton, Julie, Déprez, Benoît P., Déprez-Poulain, Rébecca F.
Published in Bioorganic & medicinal chemistry letters (15.09.2008)
Published in Bioorganic & medicinal chemistry letters (15.09.2008)
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Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses
Brier, Lucile, Hassan, Haitham, Hanoulle, Xavier, Landry, Valerie, Moschidi, Danai, Desmarets, Lowiese, Rouillé, Yves, Dumont, Julie, Herledan, Adrien, Warenghem, Sandrine, Piveteau, Catherine, Carré, Paul, Ikherbane, Sarah, Cantrelle, François-Xavier, Dupré, Elian, Dubuisson, Jean, Belouzard, Sandrine, Leroux, Florence, Deprez, Benoit, Charton, Julie
Published in European journal of medicinal chemistry (15.03.2023)
Published in European journal of medicinal chemistry (15.03.2023)
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