LXR Regulation of Brain Cholesterol: From Development to Disease
Courtney, Rebecca, Landreth, Gary E
Published in Trends in endocrinology and metabolism (01.06.2016)
Published in Trends in endocrinology and metabolism (01.06.2016)
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Journal Article
TREM2 in Neurodegenerative Diseases
Jay, Taylor R, von Saucken, Victoria E, Landreth, Gary E
Published in Molecular neurodegeneration (02.08.2017)
Published in Molecular neurodegeneration (02.08.2017)
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Journal Article
Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease
Jay, Taylor R, Hirsch, Anna M, Broihier, Margaret L, Miller, Crystal M, Neilson, Lee E, Ransohoff, Richard M, Lamb, Bruce T, Landreth, Gary E
Published in The Journal of neuroscience (18.01.2017)
Published in The Journal of neuroscience (18.01.2017)
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Journal Article
Microglia and inflammation in Alzheimer's disease
Mandrekar-Colucci, Shweta, Landreth, Gary E
Published in CNS & neurological disorders drug targets (01.04.2010)
Published in CNS & neurological disorders drug targets (01.04.2010)
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Journal Article
TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models
Jay, Taylor R, Miller, Crystal M, Cheng, Paul J, Graham, Leah C, Bemiller, Shane, Broihier, Margaret L, Xu, Guixiang, Margevicius, Daniel, Karlo, J Colleen, Sousa, Gregory L, Cotleur, Anne C, Butovsky, Oleg, Bekris, Lynn, Staugaitis, Susan M, Leverenz, James B, Pimplikar, Sanjay W, Landreth, Gary E, Howell, Gareth R, Ransohoff, Richard M, Lamb, Bruce T
Published in The Journal of experimental medicine (09.03.2015)
Published in The Journal of experimental medicine (09.03.2015)
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Journal Article
INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia
Tsai, Andy P., Lin, Peter Bor-Chian, Dong, Chuanpeng, Moutinho, Miguel, Casali, Brad T., Liu, Yunlong, Lamb, Bruce T., Landreth, Gary E., Oblak, Adrian L., Nho, Kwangsik
Published in Neurobiology of disease (01.06.2021)
Published in Neurobiology of disease (01.06.2021)
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Journal Article
Nuclear receptors license phagocytosis by trem2+ myeloid cells in mouse models of Alzheimer's disease
Savage, Julie C, Jay, Taylor, Goduni, Elanda, Quigley, Caitlin, Mariani, Monica M, Malm, Tarja, Ransohoff, Richard M, Lamb, Bruce T, Landreth, Gary E
Published in The Journal of neuroscience (22.04.2015)
Published in The Journal of neuroscience (22.04.2015)
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Journal Article
The 16p11.2 deletion mouse model of autism exhibits altered cortical progenitor proliferation and brain cytoarchitecture linked to the ERK MAPK pathway
Pucilowska, Joanna, Vithayathil, Joseph, Tavares, Emmanuel J, Kelly, Caitlin, Karlo, J Colleen, Landreth, Gary E
Published in The Journal of neuroscience (18.02.2015)
Published in The Journal of neuroscience (18.02.2015)
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Journal Article
TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy
Bemiller, Shane M, McCray, Tyler J, Allan, Kevin, Formica, Shane V, Xu, Guixiang, Wilson, Gina, Kokiko-Cochran, Olga N, Crish, Samuel D, Lasagna-Reeves, Cristian A, Ransohoff, Richard M, Landreth, Gary E, Lamb, Bruce T
Published in Molecular neurodegeneration (16.10.2017)
Published in Molecular neurodegeneration (16.10.2017)
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Journal Article
The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease
Moutinho, Miguel, Puntambekar, Shweta S, Tsai, Andy P, Coronel, Israel, Lin, Peter B, Casali, Brad T, Martinez, Pablo, Oblak, Adrian L, Lasagna-Reeves, Cristian A, Lamb, Bruce T, Landreth, Gary E
Published in Science translational medicine (23.03.2022)
Published in Science translational medicine (23.03.2022)
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Journal Article
Extracellular Signal-Regulated Kinase 1 (ERK1) and ERK2 Play Essential Roles in Osteoblast Differentiation and in Supporting Osteoclastogenesis
Matsushita, Takehiko, Chan, Yuk Yu, Kawanami, Aya, Balmes, Gener, Landreth, Gary E., Murakami, Shunichi
Published in Molecular and Cellular Biology (01.11.2009)
Published in Molecular and Cellular Biology (01.11.2009)
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Journal Article
The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease
Cheng-Hathaway, Paul J, Reed-Geaghan, Erin G, Jay, Taylor R, Casali, Brad T, Bemiller, Shane M, Puntambekar, Shweta S, von Saucken, Victoria E, Williams, Roxanne Y, Karlo, J Colleen, Moutinho, Miguel, Xu, Guixiang, Ransohoff, Richard M, Lamb, Bruce T, Landreth, Gary E
Published in Molecular neurodegeneration (01.06.2018)
Published in Molecular neurodegeneration (01.06.2018)
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Journal Article