HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5
Elorza, Ainara, Soro-Arnáiz, Inés, Meléndez-Rodríguez, Florinda, Rodríguez-Vaello, Victoria, Marsboom, Glenn, de Cárcer, Guillermo, Acosta-Iborra, Bárbara, Albacete-Albacete, Lucas, Ordóñez, Angel, Serrano-Oviedo, Leticia, Giménez-Bachs, Jose Miguel, Vara-Vega, Alicia, Salinas, Antonio, Sánchez-Prieto, Ricardo, Martín del Río, Rafael, Sánchez-Madrid, Francisco, Malumbres, Marcos, Landázuri, Manuel O., Aragonés, Julián
Published in Molecular cell (14.12.2012)
Published in Molecular cell (14.12.2012)
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Journal Article
Induction of the Mitochondrial NDUFA4L2 Protein by HIF-1α Decreases Oxygen Consumption by Inhibiting Complex I Activity
Tello, Daniel, Balsa, Eduardo, Acosta-Iborra, Bárbara, Fuertes-Yebra, Esther, Elorza, Ainara, Ordóñez, Ángel, Corral-Escariz, María, Soro, Inés, López-Bernardo, Elia, Perales-Clemente, Ester, Martínez-Ruiz, Antonio, Enríquez, José Antonio, Aragonés, Julián, Cadenas, Susana, Landázuri, Manuel O.
Published in Cell metabolism (07.12.2011)
Published in Cell metabolism (07.12.2011)
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Mitochondrial reprogramming through cardiac oxygen sensors in ischaemic heart disease
Cadenas, Susana, Aragonés, Julián, Landázuri, Manuel O.
Published in Cardiovascular research (01.11.2010)
Published in Cardiovascular research (01.11.2010)
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Journal Article
Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival
Conde, Elisa, Alegre, Laura, Blanco-Sánchez, Ignacio, Sáenz-Morales, David, Aguado-Fraile, Elia, Ponte, Belén, Ramos, Edurne, Sáiz, Ana, Jiménez, Carlos, Ordoñez, Angel, López-Cabrera, Manuel, del Peso, Luis, de Landázuri, Manuel O, Liaño, Fernando, Selgas, Rafael, Sanchez-Tomero, Jose Antonio, García-Bermejo, María Laura
Published in PloS one (14.03.2012)
Published in PloS one (14.03.2012)
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Journal Article
Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor
Acosta-Iborra, Bárbara, Elorza, Ainara, Olazabal, Isabel M, Martín-Cofreces, Noa B, Martin-Puig, Silvia, Miró, Marta, Calzada, María J, Aragonés, Julián, Sánchez-Madrid, Francisco, Landázuri, Manuel O
Published in The Journal of immunology (1950) (01.03.2009)
Published in The Journal of immunology (1950) (01.03.2009)
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Journal Article
Acute Vhl gene inactivation induces cardiac HIF-dependent erythropoietin gene expression
Miró-Murillo, Marta, Elorza, Ainara, Soro-Arnáiz, Inés, Albacete-Albacete, Lucas, Ordoñez, Angel, Balsa, Eduardo, Vara-Vega, Alicia, Vázquez, Silvia, Fuertes, Esther, Fernández-Criado, Carmen, Landázuri, Manuel O, Aragonés, Julián
Published in PloS one (21.07.2011)
Published in PloS one (21.07.2011)
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Journal Article
Analysis of HIF-prolyl hydroxylases binding to substrates
Landázuri, Manuel O., Vara-Vega, Alicia, Vitón, Mariano, Cuevas, Yolanda, del Peso, Luis
Published in Biochemical and biophysical research communications (15.12.2006)
Published in Biochemical and biophysical research communications (15.12.2006)
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Journal Article
c-Jun and Hypoxia-Inducible Factor 1 Functionally Cooperate in Hypoxia-Induced Gene Transcription
Alfranca, Arántzazu, Gutiérrez, M. Dolores, Vara, Alicia, Aragonés, Julián, Vidal, Felipe, Landázuri, Manuel O.
Published in Molecular and Cellular Biology (01.01.2002)
Published in Molecular and Cellular Biology (01.01.2002)
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Journal Article
The transcription factor Nrf2 promotes survival by enhancing the expression of uncoupling protein 3 under conditions of oxidative stress
Anedda, Andrea, López-Bernardo, Elia, Acosta-Iborra, Bárbara, Saadeh Suleiman, M., Landázuri, Manuel O., Cadenas, Susana
Published in Free radical biology & medicine (01.08.2013)
Published in Free radical biology & medicine (01.08.2013)
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Journal Article
Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1
Pescador, Nuria, Villar, Diego, Cifuentes, Daniel, Garcia-Rocha, Mar, Ortiz-Barahona, Amaya, Vazquez, Silvia, Ordoñez, Angel, Cuevas, Yolanda, Saez-Morales, David, Garcia-Bermejo, Maria Laura, Landazuri, Manuel O, Guinovart, Joan, del Peso, Luis
Published in PloS one (12.03.2010)
Published in PloS one (12.03.2010)
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Journal Article
Down-regulation of Hypoxia-inducible Factor-2 in PC12 Cells by Nerve Growth Factor Stimulation
Naranjo-Suárez, Salvador, Castellanos, María Carmen, Álvarez-Tejado, Miguel, Vara, Alicia, Landázuri, Manuel O., del Peso, Luis
Published in The Journal of biological chemistry (22.08.2003)
Published in The Journal of biological chemistry (22.08.2003)
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Journal Article
Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene
Pescador, Nuria, Cuevas, Yolanda, Naranjo, Salvador, Alcaide, Marisa, Villar, Diego, Landázuri, Manuel O, Del Peso, Luis
Published in Biochemical journal (15.08.2005)
Published in Biochemical journal (15.08.2005)
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Journal Article
The von Hippel Lindau/Hypoxia-inducible Factor (HIF) Pathway Regulates the Transcription of the HIF-Proline Hydroxylase Genes in Response to Low Oxygen
del Peso, Luis, Castellanos, María C., Temes, Elisa, Martín-Puig, Silvia, Cuevas, Yolanda, Olmos, Gemma, Landázuri, Manuel O.
Published in The Journal of biological chemistry (05.12.2003)
Published in The Journal of biological chemistry (05.12.2003)
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Journal Article
von Hippel-Lindau tumor suppressor protein regulates the assembly of intercellular junctions in renal cancer cells through hypoxia-inducible factor-independent mechanisms
Calzada, Maria J, Esteban, Miguel A, Feijoo-Cuaresma, Monica, Castellanos, Maria C, Naranjo-Suárez, Salvador, Temes, Elisa, Méndez, Fernando, Yánez-Mo, Maria, Ohh, Michael, Landázuri, Manuel O
Published in Cancer research (Chicago, Ill.) (01.02.2006)
Published in Cancer research (Chicago, Ill.) (01.02.2006)
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Journal Article
Lack of Evidence for the Involvement of the Phosphoinositide 3-Kinase/Akt Pathway in the Activation of Hypoxia-inducible Factors by Low Oxygen Tension
Alvarez-Tejado, Miguel, Alfranca, Arántzazu, Aragonés, Julian, Vara, Alicia, Landázuri, Manuel O., del Peso, Luis
Published in The Journal of biological chemistry (19.04.2002)
Published in The Journal of biological chemistry (19.04.2002)
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Journal Article
Inadequate Activation of the GTPase RhoA Contributes to the Lack of Fibronectin Matrix Assembly in von Hippel-Lindau Protein-defective Renal Cancer Cells
Feijóo-Cuaresma, Monica, Méndez, Fernando, Maqueda, Alfredo, Esteban, Miguel A., Naranjo-Suarez, Salvador, Castellanos, Maria C., del Cerro, Mercedes Hernández, Vazquez, Silvia N., García-Pardo, Angeles, Landázuri, Manuel O., Calzada, Maria J.
Published in The Journal of biological chemistry (05.09.2008)
Published in The Journal of biological chemistry (05.09.2008)
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Journal Article
Evidence for the Involvement of Diacylglycerol Kinase in the Activation of Hypoxia-inducible Transcription Factor 1 by Low Oxygen Tension
Aragonés, Julián, Jones, David R., Martı́n, Silvia, Juan, Miguel Angel San, Alfranca, Arántzazu, Vidal, Felipe, Vara, Alicia, Mérida, Isabel, Landázuri, Manuel O.
Published in The Journal of biological chemistry (30.03.2001)
Published in The Journal of biological chemistry (30.03.2001)
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