Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2
Sprowl, Jason A., Ciarimboli, Giuliano, Lancaster, Cynthia S., Giovinazzo, Hugh, Gibson, Alice A., Du, Guoqing, Janke, Laura J., Cavaletti, Guido, Shields, Anthony F., Sparreboom, Alex
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2013)
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Proximal Tubular Secretion of Creatinine by Organic Cation Transporter OCT2 in Cancer Patients
CIARIMBOLI, Giuliano, LANCASTER, Cynthia S, PUI, Ching-Hon, RELLING, Mary V, HERRMANN, Edwin, SPARREBOOM, Alex, SCHLATTER, Eberhard, FRANKE, Ryan M, SPROWL, Jason A, PAVENSTÄDT, Hermann, MASSMANN, Vivian, GUCKEL, Denise, MATHIJSSEN, Ron H. J, WENJIAN YANG
Published in Clinical cancer research (15.02.2012)
Published in Clinical cancer research (15.02.2012)
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Journal Article
Cisplatin-Induced Renal Injury Is Independently Mediated by OCT2 and p53
SPROWL, Jason A, LANCASTER, Cynthia S, CIARIMBOLI, Giuliano, SPARREBOOM, Alex, PABLA, Navjotsingh, HERMANN, Edwin, KOSLOSKE, Ashley M, GIBSON, Alice A, LIE LI, ZEEH, Dorothea, SCHLATTER, Eberhard, JANKE, Laura J
Published in Clinical cancer research (01.08.2014)
Published in Clinical cancer research (01.08.2014)
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Modulation of OATP1B-type transporter function alters cellular uptake and disposition of platinum chemotherapeutics
Lancaster, Cynthia S, Sprowl, Jason A, Walker, Aisha L, Hu, Shuiying, Gibson, Alice A, Sparreboom, Alex
Published in Molecular cancer therapeutics (01.08.2013)
Published in Molecular cancer therapeutics (01.08.2013)
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Journal Article
Influence of polymorphic OATP1B-type carriers on the disposition of docetaxel
de Graan, Anne-Joy M, Lancaster, Cynthia S, Obaidat, Amanda, Hagenbuch, Bruno, Elens, Laure, Friberg, Lena E, de Bruijn, Peter, Hu, Shuiying, Gibson, Alice A, Bruun, Gitte H, Corydon, Thomas J, Mikkelsen, Torben S, Walker, Aisha L, Du, Guoqing, Loos, Walter J, van Schaik, Ron H N, Baker, Sharyn D, Mathijssen, Ron H J, Sparreboom, Alex
Published in Clinical cancer research (15.08.2012)
Published in Clinical cancer research (15.08.2012)
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Journal Article
Inhibition of OCTN2-mediated transport of carnitine by etoposide
Hu, Chaoxin, Lancaster, Cynthia S, Zuo, Zhili, Hu, Shuiying, Chen, Zhaoyuan, Rubnitz, Jeffrey E, Baker, Sharyn D, Sparreboom, Alex
Published in Molecular cancer therapeutics (01.04.2012)
Published in Molecular cancer therapeutics (01.04.2012)
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Journal Article
TOR Signaling Is a Determinant of Cell Survival in Response to DNA Damage
Shen, Changxian, Lancaster, Cynthia S., Shi, Bin, Guo, Hong, Thimmaiah, Padma, Bjornsti, Mary-Ann
Published in Molecular and Cellular Biology (01.10.2007)
Published in Molecular and Cellular Biology (01.10.2007)
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Journal Article
Cisplatin-Induced Downregulation of OCTN2 Affects Carnitine Wasting
LANCASTER, Cynthia S, CHAOXIN HU, FRANKE, Ryan M, FILIPSKI, Kelly K, ORWICK, Shelley J, ZHAOYUAN CHEN, ZHILI ZUO, LOOS, Walter J, SPARREBOOM, Alex
Published in Clinical cancer research (01.10.2010)
Published in Clinical cancer research (01.10.2010)
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Journal Article
Influence of Oct1/Oct2-Deficiency on Cisplatin-Induced Changes in Urinary N-Acetyl-β-D-Glucosaminidase
FRANKE, Ryan M, KOSLOSKE, Ashley M, LANCASTER, Cynthia S, FILIPSKI, Kelly K, CHAOXIN HU, ZOLK, Oliver, MATHIJSSEN, Ron H, SPARREBOOM, Alex
Published in Clinical cancer research (15.08.2010)
Published in Clinical cancer research (15.08.2010)
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Journal Article
Organic Anion Transporting Polypeptide 1B (OATP1B) Transporters Modulate Hydroxyurea Pharmacokinetics
Walker, Aisha L., Lancaster, Cynthia S, Ware, Russell E., Sparreboom, Alex
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Influence of Polymorphic OATP1 B-Type Carriers on the Disposition of Docetaxel
DE GRAAN, Anne-Joy M, LANCASTER, Cynthia S, CORYDON, Thomas J, MIKKELSEN, Torben S, WALKER, Aisha L, GUOQING DU, LOOS, Walter J, SCHAIK, Ron H. N. Van, BAKER, Sharyn D, MATHIJSSEN, Ron H. J, SPARREBOOM, Alex, OBAIDAT, Amanda, HAGENBUCH, Bruno, ELENS, Laure, FRIBERG, Lena E, BRUIJN, Peter De, SHUIYING HU, GIBSON, Alice A, BRUUN, Gitte H
Published in Clinical cancer research (2012)
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Published in Clinical cancer research (2012)
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