Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells
Grevet, Jeremy D, Lan, Xianjiang, Hamagami, Nicole, Edwards, Christopher R, Sankaranarayanan, Laavanya, Ji, Xinjun, Bhardwaj, Saurabh K, Face, Carolyne J, Posocco, David F, Abdulmalik, Osheiza, Keller, Cheryl A, Giardine, Belinda, Sidoli, Simone, Garcia, Ben A, Chou, Stella T, Liebhaber, Stephen A, Hardison, Ross C, Shi, Junwei, Blobel, Gerd A
Published in Science (American Association for the Advancement of Science) (20.07.2018)
Published in Science (American Association for the Advancement of Science) (20.07.2018)
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ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth
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Published in Molecular cell (19.05.2016)
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Comparative analysis of duplicated sox21 genes in zebrafish
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Published in Development, growth & differentiation (01.04.2011)
Published in Development, growth & differentiation (01.04.2011)
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ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression
Lan, Xianjiang, Ren, Ren, Feng, Ruopeng, Ly, Lana C., Lan, Yemin, Zhang, Zhe, Aboreden, Nicholas, Qin, Kunhua, Horton, John R., Grevet, Jeremy D., Mayuranathan, Thiyagaraj, Abdulmalik, Osheiza, Keller, Cheryl A., Giardine, Belinda, Hardison, Ross C., Crossley, Merlin, Weiss, Mitchell J., Cheng, Xiaodong, Shi, Junwei, Blobel, Gerd A.
Published in Molecular cell (21.01.2021)
Published in Molecular cell (21.01.2021)
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Molecular basis of polycomb group protein–mediated fetal hemoglobin repression
Qin, Kunhua, Lan, Xianjiang, Huang, Peng, Saari, Megan S., Khandros, Eugene, Keller, Cheryl A., Giardine, Belinda, Abdulmalik, Osheiza, Shi, Junwei, Hardison, Ross C., Blobel, Gerd A.
Published in Blood (01.06.2023)
Published in Blood (01.06.2023)
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The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression
Huang, Peng, Peslak, Scott A., Lan, Xianjiang, Khandros, Eugene, Yano, Jennifer A., Sharma, Malini, Keller, Cheryl A., Giardine, Belinda, Qin, Kunhua, Abdulmalik, Osheiza, Hardison, Ross C., Shi, Junwei, Blobel, Gerd A.
Published in Blood (11.06.2020)
Published in Blood (11.06.2020)
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Mechanisms of Polycomb Group Protein-Mediated Fetal Hemoglobin Silencing
Qin, Kunhua, Huang, Peng, Lan, Xianjiang, Saari, Megan S., Khandros, Eugene, Abdulmalik, Osheiza Y., Keller, Cheryl A., Giardine, Belinda M., Hardison, Ross C., Shi, Junwei, Blobel, Gerd A.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Interrogating RNA Binding Proteins as Novel Regulators of Fetal Hemoglobin Expression
Wakabayashi, Aoi, Grevet, Jeremy D., Lan, Xianjiang, Sharma, Malini, Shi, Junwei, Blobel, Gerd A.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription
Huang, Peng, Peslak, Scott A., Ren, Ren, Khandros, Eugene, Qin, Kunhua, Keller, Cheryl A., Giardine, Belinda, Bell, Henry W., Lan, Xianjiang, Sharma, Malini, Horton, John R., Abdulmalik, Osheiza, Chou, Stella T., Shi, Junwei, Crossley, Merlin, Hardison, Ross C., Cheng, Xiaodong, Blobel, Gerd A.
Published in Nature genetics (01.09.2022)
Published in Nature genetics (01.09.2022)
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Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410-DNA interaction using small angle X-ray scattering
Kaur, Gundeep, Ren, Ren, Hammel, Michal, Horton, John R, Yang, Jie, Cao, Yu, He, Chenxi, Lan, Fei, Lan, Xianjiang, Blobel, Gerd A, Blumenthal, Robert M, Zhang, Xing, Cheng, Xiaodong
Published in Nucleic acids research (28.02.2023)
Published in Nucleic acids research (28.02.2023)
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Heme-Regulated Inhibitor (HRI) Loss and Pharmacologic Treatments Cooperate to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation
Peslak, Scott A., Grevet, Jeremy D., Lan, Xianjiang, Abdulmalik, Osheiza, Shi, Junwei, Blobel, Gerd A.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells
Qin, Kunhua, Huang, Peng, Feng, Ruopeng, Keller, Cheryl A., Peslak, Scott A., Khandros, Eugene, Saari, Megan S., Lan, Xianjiang, Mayuranathan, Thiyagaraj, Doerfler, Phillip A., Abdulmalik, Osheiza, Giardine, Belinda, Chou, Stella T., Shi, Junwei, Hardison, Ross C., Weiss, Mitchell J., Blobel, Gerd A.
Published in Nature genetics (01.06.2022)
Published in Nature genetics (01.06.2022)
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Author Correction: HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription
Huang, Peng, Peslak, Scott A., Ren, Ren, Khandros, Eugene, Qin, Kunhua, Keller, Cheryl A., Giardine, Belinda, Bell, Henry W., Lan, Xianjiang, Sharma, Malini, Horton, John R., Abdulmalik, Osheiza, Chou, Stella T., Shi, Junwei, Crossley, Merlin, Hardison, Ross C., Cheng, Xiaodong, Blobel, Gerd A.
Published in Nature genetics (01.09.2023)
Published in Nature genetics (01.09.2023)
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Journal Article
HIC2 Controls Developmental Hemoglobin Switching By Repressing BCL11A Transcription
Huang, Peng, Peslak, Scott A., Khandros, Eugene, Lan, Xianjiang, Qin, Kunhua, Sharma, Malini, Keller, Cheryl A., Giardine, Belinda, Abdulmalik, Osheiza, Chou, Stella T., Shi, Junwei, Hardison, Ross C., Blobel, Gerd A.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Heme-Regulated Inhibitor (HRI) Activates Transcription Factor ATF4 to Promote BCL11A Transcription and Fetal Hemoglobin Silencing
Huang, Peng, Peslak, Scott A., Lan, Xianjiang, Khandros, Eugene, Sharma, Malini, Qin, Kunhua, Keller, Cheryl A, Giardine, Belinda, Shi, Junwei, Hardison, Ross C., Blobel, Gerd A.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Heme-Regulated Inhibitor (HRI) Depletion Cooperates with Pharmacologic Inducers to Strongly Elevate Fetal Hemoglobin and Reduce Sickle Cell Formation
Peslak, Scott A., Lan, Xianjiang, Khandros, Eugene, Huang, Peng, Yano, Jennifer A., Grevet, Jeremy D., Abdulmalik, Osheiza, Keller, Cheryl A, Hardison, Ross C., Shi, Junwei, Blobel, Gerd A.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Publisher Correction: Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells
Qin, Kunhua, Huang, Peng, Feng, Ruopeng, Keller, Cheryl A., Peslak, Scott A., Khandros, Eugene, Saari, Megan S., Lan, Xianjiang, Mayuranathan, Thiyagaraj, Doerfler, Phillip A., Abdulmalik, Osheiza, Giardine, Belinda, Chou, Stella T., Shi, Junwei, Hardison, Ross C., Weiss, Mitchell J., Blobel, Gerd A.
Published in Nature genetics (01.06.2022)
Published in Nature genetics (01.06.2022)
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Domain-Focused CRISPR-Cas9 Screen Identifies the E3 Ubiquitin Ligase Substrate Adaptor Protein SPOP as a Novel Repressor of Fetal Hemoglobin
Lan, Xianjiang, Khandros, Eugene, Grevet, Jeremy D., Peslak, Scott A., Bhardwaj, Saurabh, Keller, Cheryl A., Giardine, Belinda, Garcia, Ben A., Hardison, Ross C., Shi, Junwei, Blobel, Gerd A.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression
Lan, Xianjiang, Ren, Ren, Feng, Ruopeng, Ly, Lana C, Lan, Yemin, Zhang, Zhe, Aboreden, Nicholas, Qin, Kunhua, Horton, John R, Grevet, Jeremy D., Mayuranathan, Thiyagaraj, Abdulmalik, Osheiza, Keller, Cheryl A., Giardine, Belinda, Hardison, Ross C., Crossley, Merlin, Weiss, Mitchell J., Cheng, Xiaodong, Shi, Junwei, Blobel, Gerd A.
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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