2-Deoxy-d-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion
Xi, Haibin, Kurtoglu, Metin, Liu, Huaping, Wangpaichitr, Medhi, You, Min, Liu, Xiongfei, Savaraj, Niramol, Lampidis, Theodore J.
Published in Cancer chemotherapy and pharmacology (01.04.2011)
Published in Cancer chemotherapy and pharmacology (01.04.2011)
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2-deoxy-d-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo
MASCHEK, Gregory, SAVARAJ, Niramol, PRIEBE, Waldemar, BRAUNSCHWEIGER, Paul, HAMILTON, Kara, TIDMARSH, George F, DE YOUNG, Linda R, LAMPIDIS, Theodore J
Published in Cancer research (Chicago, Ill.) (2004)
Published in Cancer research (Chicago, Ill.) (2004)
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Journal Article
Antiangiogenic activity of 2-deoxy-D-glucose
Merchan, Jaime R, Kovács, Krisztina, Railsback, Jaclyn W, Kurtoglu, Metin, Jing, Yuqi, Piña, Yolanda, Gao, Ningguo, Murray, Timothy G, Lehrman, Mark A, Lampidis, Theodore J
Published in PloS one (27.10.2010)
Published in PloS one (27.10.2010)
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A phase I dose-escalation trial of 2-deoxy-d-glucose alone or combined with docetaxel in patients with advanced solid tumors
Raez, Luis E., Papadopoulos, Kyriakos, Ricart, Alejandro D., Chiorean, E. Gabriella, DiPaola, Robert S., Stein, Mark N., Rocha Lima, Caio M., Schlesselman, James J., Tolba, Khaled, Langmuir, Virginia K., Kroll, Stewart, Jung, Donald T., Kurtoglu, Metin, Rosenblatt, Joseph, Lampidis, Theodore J.
Published in Cancer chemotherapy and pharmacology (01.02.2013)
Published in Cancer chemotherapy and pharmacology (01.02.2013)
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Journal Article
Under normoxia, 2-deoxy-d-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation
Kurtoglu, Metin, Gao, Ningguo, Shang, Jie, Maher, Johnathan C, Lehrman, Mark A, Wangpaichitr, Medhi, Savaraj, Niramol, Lane, Andrew N, Lampidis, Theodore J
Published in Molecular cancer therapeutics (01.11.2007)
Published in Molecular cancer therapeutics (01.11.2007)
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Journal Article
The relationship of thioredoxin-1 and cisplatin resistance: its impact on ROS and oxidative metabolism in lung cancer cells
Wangpaichitr, Medhi, Sullivan, Elizabeth J, Theodoropoulos, George, Wu, Chunjing, You, Min, Feun, Lynn G, Lampidis, Theodore J, Kuo, Macus T, Savaraj, Niramol
Published in Molecular cancer therapeutics (01.03.2012)
Published in Molecular cancer therapeutics (01.03.2012)
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Journal Article
Targeting the Kynurenine Pathway for the Treatment of Cisplatin-Resistant Lung Cancer
Nguyen, Dan J M, Theodoropoulos, George, Li, Ying-Ying, Wu, Chunjing, Sha, Wei, Feun, Lynn G, Lampidis, Theodore J, Savaraj, Niramol, Wangpaichitr, Medhi
Published in Molecular cancer research (01.01.2020)
Published in Molecular cancer research (01.01.2020)
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Journal Article
Activation of the Unfolded Protein Response by 2-Deoxy-d-Glucose Inhibits Kaposi's Sarcoma-Associated Herpesvirus Replication and Gene Expression
LEUNG, Howard J, DURAN, Elda M, KURTOGLU, Metin, ANDREANSKY, Samita, LAMPIDIS, Theodore J, MESRI, Enrique A
Published in Antimicrobial Agents and Chemotherapy (01.11.2012)
Published in Antimicrobial Agents and Chemotherapy (01.11.2012)
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Journal Article
The evolutionarily conserved arginyltransferase 1 mediates a pVHL-independent oxygen-sensing pathway in mammalian cells
Moorthy, Balaji T., Jiang, Chunhua, Patel, Devang M., Ban, Yuguang, O’Shea, Corin R., Kumar, Akhilesh, Yuan, Tan, Birnbaum, Michael D., Gomes, Aldrin V., Chen, Xi, Fontanesi, Flavia, Lampidis, Theodore J., Barrientos, Antoni, Zhang, Fangliang
Published in Developmental cell (14.03.2022)
Published in Developmental cell (14.03.2022)
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Journal Article
Inhibition of Akt potentiates 2-DG-induced apoptosis via downregulation of UPR in acute lymphoblastic leukemia
DeSalvo, Joanna, Kuznetsov, Jeffim N, Du, Jianfeng, Leclerc, Gilles M, Leclerc, Guy J, Lampidis, Theodore J, Barredo, Julio C
Published in Molecular cancer research (01.07.2012)
Published in Molecular cancer research (01.07.2012)
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Journal Article
Abstract 1252: Glucose and Mannose sugar analogs negatively affect KSHV replication by inhibiting N-Glycosylation and inducing the Unfolded Protein Response
McDonald, Christian, Schlesinger, Marianna, Ahuja, Anuj, Alvarez, Carolina, Nunez, Zelmira, Naipauer, Julian, Mesri, Enrique, Lampidis, Theodore
Published in The Journal of biological chemistry (2023)
Published in The Journal of biological chemistry (2023)
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Hypersensitization of Tumor Cells to Glycolytic Inhibitors
Liu, H, Hu, Y. P, Savaraj, N, Priebe, W, Lampidis, T. J
Published in Biochemistry (Easton) (08.05.2001)
Published in Biochemistry (Easton) (08.05.2001)
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Journal Article
Regulation of Mitochondrial Respiratory Chain Complex Levels, Organization, and Function by Arginyltransferase 1
Jiang, Chunhua, Moorthy, Balaji T, Patel, Devang M, Kumar, Akhilesh, Morgan, William M, Alfonso, Belkis, Huang, Jingyu, Lampidis, Theodore J, Isom, Daniel G, Barrientos, Antoni, Fontanesi, Flavia, Zhang, Fangliang
Published in Frontiers in cell and developmental biology (21.12.2020)
Published in Frontiers in cell and developmental biology (21.12.2020)
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