ETMR: a tumor entity in its infancy
Lambo, Sander, von Hoff, Katja, Korshunov, Andrey, Pfister, Stefan M., Kool, Marcel
Published in Acta neuropathologica (01.09.2020)
Published in Acta neuropathologica (01.09.2020)
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Journal Article
Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme
Feng, Weijun, Kawauchi, Daisuke, Körkel-Qu, Huiqin, Deng, Huan, Serger, Elisabeth, Sieber, Laura, Lieberman, Jenna Ariel, Jimeno-González, Silvia, Lambo, Sander, Hanna, Bola S, Harim, Yassin, Jansen, Malin, Neuerburg, Anna, Friesen, Olga, Zuckermann, Marc, Rajendran, Vijayanad, Gronych, Jan, Ayrault, Olivier, Korshunov, Andrey, Jones, David T W, Kool, Marcel, Northcott, Paul A, Lichter, Peter, Cortés-Ledesma, Felipe, Pfister, Stefan M, Liu, Hai-Kun
Published in Nature communications (20.03.2017)
Published in Nature communications (20.03.2017)
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Journal Article
Potential Importance of Early Focal Radiotherapy Following Gross Total Resection for Long-Term Survival in Children With Embryonal Tumors With Multilayered Rosettes
Mayr, Lisa, Gojo, Johannes, Peyrl, Andreas, Azizi, Amedeo A, Stepien, Natalia M, Pletschko, Thomas, Czech, Thomas, Dorfer, Christian, Lambo, Sander, Dieckmann, Karin, Haberler, Christine, Kool, Marcel, Slavc, Irene
Published in Frontiers in oncology (17.12.2020)
Published in Frontiers in oncology (17.12.2020)
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Journal Article
Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours
Nabbi, Arash, Beck, Pengbo, Delaidelli, Alberto, Oldridge, Derek A., Sudhaman, Sumedha, Zhu, Kelsey, Yang, S. Y. Cindy, Mulder, David T., Bruce, Jeffrey P., Paulson, Joseph N., Raman, Pichai, Zhu, Yuankun, Resnick, Adam C., Sorensen, Poul H., Sill, Martin, Brabetz, Sebastian, Lambo, Sander, Malkin, David, Johann, Pascal D., Kool, Marcel, Jones, David T. W., Pfister, Stefan M., Jäger, Natalie, Pugh, Trevor J.
Published in Genome medicine (07.09.2023)
Published in Genome medicine (07.09.2023)
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Journal Article
A Longitudinal Single-Cell Atlas of Treatment Response in Pediatric AML
Lambo, Sander, Trinh, Diane L., Ries, Rhonda E, Jin, Dan, Setiadi, Audi, Ng, Michelle, Leblanc, Veronique G., Vercauteren, Suzanne, Meshinchi, Soheil, Marra, Marco
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
EPCO-45. CELLULAR HIERARCHIES OF ETMR ARE SHAPED BY ONCOGENIC MICRORNAS AND RECEPTOR-LIGAND INTERACTIONS
Gabler, Lisa, Beck, Alexander, Cruzeiro, Gustavo, Lambo, Sander, Englinger, Bernhard, Shaw, McKenzie L, Hack, Olivia, Chi, Susan, Alexandrescu, Sanda, Gojo, Johannes, Kool, Marcel, Hovestadt, Volker, Filbin, Mariella
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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Journal Article
MODL-02. TARGETING REPLICATION STRESS IN PEDIATRIC BRAIN TUMORS
Krausert, Sonja, Lambo, Sander, Mack, Norman, Schwalm, Benjamin, Pfister, Stefan, Kool, Marcel
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
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Journal Article
ETMR-13. NFI GENES IN ETMR TUMORIGENESIS AND NEURODEVELOPMENT
Bunt, Jens, Lambo, Sander, Lim, Jonathan, Mauermann, Monika, Pfister, Stefan, Richards, Linda, Kool, Marcel
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
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Journal Article
A longitudinal single-cell atlas of treatment response in pediatric AML
Lambo, Sander, Trinh, Diane L, Ries, Rhonda E, Jin, Dan, Setiadi, Audi, Ng, Michelle, Leblanc, Veronique G, Loken, Michael R, Brodersen, Lisa E, Dai, Fangyan, Pardo, Laura M, Ma, Xiaotu, Vercauteren, Suzanne M, Meshinchi, Soheil, Marra, Marco A
Published in Cancer cell (11.12.2023)
Published in Cancer cell (11.12.2023)
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Journal Article
ETMR-like infantile cerebellar embryonal tumors in the extended morphologic spectrum of DICER1-related tumors
Uro-Coste, Emmanuelle, Masliah-Planchon, Julien, Siegfried, Aurore, Blanluet, Maud, Lambo, Sander, Kool, Marcel, Roujeau, Thomas, Boetto, Sergio, Palenzuela, Gilles, Bertozzi, Anne-Isabelle, Gambart, Marion, Coupier, Isabelle, Oliver-Petit, Isabelle, Golmard, Lisa, Julia, Sophie, Savagner, Fréderique, Mohand-Oumoussa, Badreddine, Tauziede-Espariat, Arnault, Delisle, Marie-Bernadette, Figarella-Branger, Dominique, Bourdeaut, Franck, Rigau, Valérie
Published in Acta neuropathologica (01.01.2019)
Published in Acta neuropathologica (01.01.2019)
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Journal Article
EPCO-27. SINGLE-CELL ANALYSIS OF ETMR PATIENT SAMPLES LINKS TRANSCRIPTIONAL PHENOTYPES TO GENETIC DRIVER ALTERATIONS AND INFORMS NOVEL THERAPEUTIC STRATEGIES
Hovestadt, Volker, Beck, Alexander, Lambo, Sander, Shaw, McKenzie, Hack, Olivia A, Englinger, Bernhard, Gojo, Johannes, Madlener, Sibylle, Alexandrescu, Sanda, Pfister, Stefan, Kool, Marcel, Filbin, Mariella G
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
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Journal Article
ETMR-03. THE ROLE OF FOXR2 IN PEDIATRIC BRAIN CANCER
Schmitt-Hoffner, Felix, van Rijn, Sjoerd, Hübner, Jens-Martin, Lambo, Sander, Mauermann, Monika, Mack, Norman, Schwalm, Benjamin, Pfister, Stefan, Kool, Marcel
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
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Journal Article
Abstract A39: Molecular characterization of ETMRs reveals role for R-loop mediated genomic instability and new treatment options
Lambo, Sander, Grübner, Susanne, Rausch, Tobias, Waszak, Sebastian, Schmidt, Christin, Krausert, Sonja, Weichert, Loreen, Gorthi, Aparna, Romero, Carolina, Huang, Annie, Schueler, Julia, Korbel, Jan, Bishop, Alexander, Pfister, Stefan, Korshunov, Andrey, Kool, Marcel
Published in Cancer research (Chicago, Ill.) (15.07.2020)
Published in Cancer research (Chicago, Ill.) (15.07.2020)
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Journal Article
A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors
Neumann, Julia E, Wefers, Annika K, Lambo, Sander, Bianchi, Edoardo, Bockstaller, Marie, Dorostkar, Mario M, Meister, Valerie, Schindler, Pia, Korshunov, Andrey, von Hoff, Katja, Nowak, Johannes, Warmuth-Metz, Monika, Schneider, Marlon R, Renner-Müller, Ingrid, Merk, Daniel J, Shakarami, Mehdi, Sharma, Tanvi, Chavez, Lukas, Glass, Rainer, Chan, Jennifer A, Taketo, M Mark, Neumann, Philipp, Kool, Marcel, Schüller, Ulrich
Published in Nature medicine (01.10.2017)
Published in Nature medicine (01.10.2017)
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Journal Article
ATRT-10. SINGLE-CELL TRANSCRIPTOME ANALYSIS REVEALS CELLULAR HIERARCHIES AND THERAPEUTIC VULNERABILITIES OF ETMR
Beck, Alexander, Gabler, Lisa, Cruzeiro, Gustavo A V, Lambo, Sander, Englinger, Bernhard, Shaw, McKenzie L, Hack, Olivia A, Liu, Ilon, Junior, Carlos A O de Biagi, Haase, Rebecca D, Klenner, Marbod, Freidel, Pia, Madlener, Sibylle, Mayr, Lisa, Senfter, Daniel, Peyrl, Andreas, Slavc, Irene, Lötsch, Daniela, Dorfer, Christian, Haberler, Christine, Pfister, Stefan M, Baird, Lissa, Chi, Susan N, Alexandrescu, Sanda, Gojo, Johannes, Kool, Marcel, Hovestadt, Volker, Filbin, Mariella G
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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Journal Article
Abstract 3172: Targeting genomic instability in embryonal tumors with multilayered rosettes (ETMR)
Lambo, Sander, Korshunov, Andrey, Schmidt, Christin, Romero, Carolina, Gorthi, Aparna, Krausert, Sonja, Rausch, Tobias, Gröbner, Susanne, Brabetz, Sebastian, Waszak, Sebastian, Bishop, Alexander J., Pfister, Stefan, Kool, Marcel
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
IMMU-04. Transcriptional analysis reveals distinct microenvironmental subgroups across pediatric nervous system tumors
Nabbi, Arash, Beck, Pengbo, Delaidelli, Alberto, Oldridge, Derek A, Sudhaman, Sumedha, Zhu, Kelsey, Yang, S Y Cindy, Mulder, David T, Bruce, Jeffrey P, Paulson, Joseph N, Raman, Pichai, Zhu, Yuankun, Silll, Martin, Brabetz, Sebastian, Lambo, Sander, Johann, Pascal D, Resnick, Adam C, Sorensen, Poul H, Malkin, David, Kool, Marcel, Jones, David T W, Pfister, Stefan M, Jäger, Natalie, Pugh, Trevor J
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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Journal Article
EMBR-10. GENOMIC COMPLEXITY AND EVOLUTION OF EMBRYONAL TUMORS WITH MULTILAYERED ROSETTES (ETMR)
Lambo, Sander, Waszak, Sebastian M, Rausch, Tobias, Groebner, Susanne, Schmidt, Christin, Brabetz, Sebastian, Pfister, Stefan M, Korshunov, Andrey, Kool, Marcel
Published in Neuro-oncology (Charlottesville, Va.) (22.06.2018)
Published in Neuro-oncology (Charlottesville, Va.) (22.06.2018)
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Journal Article
Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas
Sahm, Felix, Jakobiec, Frederick A., Meyer, Jochen, Schrimpf, Daniel, Eberhart, Charles G., Hovestadt, Volker, Capper, David, Lambo, Sander, Ryzhova, Marina, Schüller, Ulrich, Zheludkova, Olga, Kumirova, Ella, Lichter, Peter, von Deimling, Andreas, Jones, David T. W., Pfister, Stefan M., Kool, Marcel, Korshunov, Andrey
Published in Genes chromosomes & cancer (01.05.2016)
Published in Genes chromosomes & cancer (01.05.2016)
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