Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
Zhang, Bin, Gaiteri, Chris, Bodea, Liviu-Gabriel, Wang, Zhi, McElwee, Joshua, Podtelezhnikov, Alexei A., Zhang, Chunsheng, Xie, Tao, Tran, Linh, Dobrin, Radu, Fluder, Eugene, Clurman, Bruce, Melquist, Stacey, Narayanan, Manikandan, Suver, Christine, Shah, Hardik, Mahajan, Milind, Gillis, Tammy, Mysore, Jayalakshmi, MacDonald, Marcy E., Lamb, John R., Bennett, David A., Molony, Cliona, Stone, David J., Gudnason, Vilmundur, Myers, Amanda J., Schadt, Eric E., Neumann, Harald, Zhu, Jun, Emilsson, Valur
Published in Cell (25.04.2013)
Published in Cell (25.04.2013)
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A genome-wide association study of serum proteins reveals shared loci with common diseases
Gudjonsson, Alexander, Gudmundsdottir, Valborg, Axelsson, Gisli T., Gudmundsson, Elias F., Jonsson, Brynjolfur G., Launer, Lenore J., Lamb, John R., Jennings, Lori L., Aspelund, Thor, Emilsson, Valur, Gudnason, Vilmundur
Published in Nature communications (25.01.2022)
Published in Nature communications (25.01.2022)
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Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases
Narayanan, Manikandan, Huynh, Jimmy L, Wang, Kai, Yang, Xia, Yoo, Seungyeul, McElwee, Joshua, Zhang, Bin, Zhang, Chunsheng, Lamb, John R, Xie, Tao, Suver, Christine, Molony, Cliona, Melquist, Stacey, Johnson, Andrew D, Fan, Guoping, Stone, David J, Schadt, Eric E, Casaccia, Patrizia, Emilsson, Valur, Zhu, Jun
Published in Molecular systems biology (01.07.2014)
Published in Molecular systems biology (01.07.2014)
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Coding and regulatory variants are associated with serum protein levels and disease
Emilsson, Valur, Gudmundsdottir, Valborg, Gudjonsson, Alexander, Jonmundsson, Thorarinn, Jonsson, Brynjolfur G., Karim, Mohd A., Ilkov, Marjan, Staley, James R., Gudmundsson, Elias F., Launer, Lenore J., Lindeman, Jan H., Morton, Nicholas M., Aspelund, Thor, Lamb, John R., Jennings, Lori L., Gudnason, Vilmundur
Published in Nature communications (25.01.2022)
Published in Nature communications (25.01.2022)
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A proteogenomic signature of age-related macular degeneration in blood
Emilsson, Valur, Gudmundsson, Elias F., Jonmundsson, Thorarinn, Jonsson, Brynjolfur G., Twarog, Michael, Gudmundsdottir, Valborg, Li, Zhiguang, Finkel, Nancy, Poor, Stephen, Liu, Xin, Esterberg, Robert, Zhang, Yiyun, Jose, Sandra, Huang, Chia-Ling, Liao, Sha-Mei, Loureiro, Joseph, Zhang, Qin, Grosskreutz, Cynthia L., Nguyen, Andrew A., Huang, Qian, Leehy, Barrett, Pitts, Rebecca, Aspelund, Thor, Lamb, John R., Jonasson, Fridbert, Launer, Lenore J., Cotch, Mary Frances, Jennings, Lori L., Gudnason, Vilmundur, Walshe, Tony E.
Published in Nature communications (13.06.2022)
Published in Nature communications (13.06.2022)
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A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations
Xie, Tao, D' Ario, Giovanni, Lamb, John R, Martin, Eric, Wang, Kai, Tejpar, Sabine, Delorenzi, Mauro, Bosman, Fred T, Roth, Arnaud D, Yan, Pu, Bougel, Stephanie, Di Narzo, Antonio Fabio, Popovici, Vlad, Budinská, Eva, Mao, Mao, Weinrich, Scott L, Rejto, Paul A, Hodgson, J Graeme
Published in PloS one (31.07.2012)
Published in PloS one (31.07.2012)
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Tau overexpression exacerbates neuropathology after repeated mild head impacts in male mice
Cheng, Hank, Deaton, Lisa M., Qiu, Minhua, Ha, Sukwon, Pacoma, Reynand, Lao, Jianmin, Tolley, Valerie, Moran, Rita, Keeton, Amber, Lamb, John R., Fathman, John, Walker, John R., Schumacher, Andrew M.
Published in Neurobiology of disease (01.02.2020)
Published in Neurobiology of disease (01.02.2020)
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microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma
Luk, John M, Burchard, Julja, Zhang, Chunsheng, Liu, Angela M, Poon, Ronnie T P, Lee, Nikki P Y, Wong, Kwong-Fai, Sham, Pak C, Lam, Brian Y, Ferguson, Mark D, Tokiwa, George, Smith, Ryan, Leeson, Brendan, Beard, Rebecca, Lamb, John R, Lim, Lee, Mao, Mao, Dai, Hongyue
Published in Molecular systems biology (24.08.2010)
Published in Molecular systems biology (24.08.2010)
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Genetics of gene expression surveyed in maize, mouse and man
Schadt, Eric E, Friend, Stephen H, Monks, Stephanie A, Drake, Thomas A, Lusis, Aldons J, Che, Nam, Colinayo, Veronica, Ruff, Thomas G, Milligan, Stephen B, Lamb, John R, Cavet, Guy, Linsley, Peter S, Mao, Mao, Stoughton, Roland B
Published in Nature (London) (20.03.2003)
Published in Nature (London) (20.03.2003)
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Serum levels of ACE2 are higher in patients with obesity and diabetes
Emilsson, Valur, Gudmundsson, Elias F., Aspelund, Thor, Jonsson, Brynjolfur G., Gudjonsson, Alexander, Launer, Lenore J., Lamb, John R., Gudmundsdottir, Valborg, Jennings, Lori L., Gudnason, Vilmundur
Published in Obesity science & practice (01.04.2021)
Published in Obesity science & practice (01.04.2021)
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Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting
Lamb, John R, Zhang, Chunsheng, Xie, Tao, Wang, Kai, Zhang, Bin, Hao, Ke, Chudin, Eugene, Fraser, Hunter B, Millstein, Joshua, Ferguson, Mark, Suver, Christine, Ivanovska, Irena, Scott, Martin, Philippar, Ulrike, Bansal, Dimple, Zhang, Zhan, Burchard, Julja, Smith, Ryan, Greenawalt, Danielle, Cleary, Michele, Derry, Jonathan, Loboda, Andrey, Watters, James, Poon, Ronnie T P, Fan, Sheung T, Yeung, Chun, Lee, Nikki P Y, Guinney, Justin, Molony, Cliona, Emilsson, Valur, Buser-Doepner, Carolyn, Zhu, Jun, Friend, Stephen, Mao, Mao, Shaw, Peter M, Dai, Hongyue, Luk, John M, Schadt, Eric E
Published in PloS one (05.07.2011)
Published in PloS one (05.07.2011)
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Characterizing dynamic changes in the human blood transcriptional network
Zhu, Jun, Chen, Yanqing, Leonardson, Amy S, Wang, Kai, Lamb, John R, Emilsson, Valur, Schadt, Eric E
Published in PLoS computational biology (01.02.2010)
Published in PLoS computational biology (01.02.2010)
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The effect of food intake on gene expression in human peripheral blood
Leonardson, Amy S., Zhu, Jun, Chen, Yanqing, Wang, Kai, Lamb, John R., Reitman, Marc, Emilsson, Valur, Schadt, Eric E.
Published in Human molecular genetics (01.01.2010)
Published in Human molecular genetics (01.01.2010)
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It’s in Our Blood: A Glimpse of Personalized Medicine
Lamb, John R., Jennings, Lori L., Gudmundsdottir, Valborg, Gudnason, Vilmundur, Emilsson, Valur
Published in Trends in molecular medicine (01.01.2021)
Published in Trends in molecular medicine (01.01.2021)
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Co-regulatory networks of human serum proteins link genetics to disease
Emilsson, Valur, Ilkov, Marjan, Lamb, John R, Finkel, Nancy, Gudmundsson, Elias F, Pitts, Rebecca, Hoover, Heather, Gudmundsdottir, Valborg, Horman, Shane R, Aspelund, Thor, Shu, Le, Trifonov, Vladimir, Sigurdsson, Sigurdur, Manolescu, Andrei, Zhu, Jun, Olafsson, Örn, Jakobsdottir, Johanna, Lesley, Scott A, To, Jeremy, Zhang, Jia, Harris, Tamara B, Launer, Lenore J, Zhang, Bin, Eiriksdottir, Gudny, Yang, Xia, Orth, Anthony P, Jennings, Lori L, Gudnason, Vilmundur
Published in Science (American Association for the Advancement of Science) (24.08.2018)
Published in Science (American Association for the Advancement of Science) (24.08.2018)
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Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes
Gudmundsdottir, Valborg, Zaghlool, Shaza B, Emilsson, Valur, Aspelund, Thor, Ilkov, Marjan, Gudmundsson, Elias F, Jonsson, Stefan M, Zilhão, Nuno R, Lamb, John R, Suhre, Karsten, Jennings, Lori L, Gudnason, Vilmundur
Published in Diabetes (New York, N.Y.) (01.08.2020)
Published in Diabetes (New York, N.Y.) (01.08.2020)
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Proteomic prediction of incident heart failure and its main subtypes
Emilsson, Valur, Jonsson, Brynjolfur G, Austin, Thomas R, Gudmundsdottir, Valborg, Axelsson, Gisli T, Frick, Elisabet A, Jonmundsson, Thorarinn, Steindorsdottir, Anna E, Loureiro, Joseph, Brody, Jennifer A, Aspelund, Thor, Launer, Lenore J, Thorgeirsson, Gudmundur, Kortekaas, Kirsten A, Lindeman, Jan H, Orth, Anthony P, Lamb, John R, Psaty, Bruce M, Kizer, Jorge R, Jennings, Lori L, Gudnason, Vilmundur
Published in European journal of heart failure (01.01.2024)
Published in European journal of heart failure (01.01.2024)
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Search for arc-produced heterofullerenes
Lamb, John R., Kwon, Youngwoo, Ruoff, Rodney S., Lamb, Lowell D.
Published in Carbon (New York) (01.08.2017)
Published in Carbon (New York) (01.08.2017)
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Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks
Drake, Thomas A, Wang, Kai, MacNeil, Douglas J, Lusis, Aldons J, Ghazalpour, Anatole, Coon, Michael, Xie, Tao, Zhu, Jun, Wang, Susanna S, Schadt, Eric E, Yang, Xia, Kleinhanz, Robert R, Castellani, Lawrence W, Qian, Su, Falkard, Brie, Lum, Pek Y, Reitman, Marc L, Majid, Sana, Mehrabian, Margarete, Zhang, Bin, Deignan, Joshua L, Zhong, Judy, Farber, Charles R, Torosyan, Gevork, Mumick, Sheena, Estrada-Smith, Daria, Zhang, Chunsheng, Dipple, Katrina M, van Nas, Atila, Lamb, John R, Qi, Hongxiu, Karlsson, Jenny
Published in Nature genetics (01.04.2009)
Published in Nature genetics (01.04.2009)
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