Discovery of 2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in BRCA-1 and -2 Mutant Tumors
Jones, Philip, Altamura, Sergio, Boueres, Julia, Ferrigno, Federica, Fonsi, Massimiliano, Giomini, Claudia, Lamartina, Stefania, Monteagudo, Edith, Ontoria, Jesus M, Orsale, Maria Vittoria, Palumbi, Maria Cecilia, Pesci, Silvia, Roscilli, Giuseppe, Scarpelli, Rita, Schultz-Fademrecht, Carsten, Toniatti, Carlo, Rowley, Michael
Published in Journal of medicinal chemistry (26.11.2009)
Published in Journal of medicinal chemistry (26.11.2009)
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Helper-dependent adenovirus for the gene therapy of proliferative retinopathies: stable gene transfer, regulated gene expression and therapeutic efficacy
Lamartina, Stefania, Cimino, Monica, Roscilli, Giuseppe, Dammassa, Ernesta, Lazzaro, Domenico, Rota, Rossella, Ciliberto, Gennaro, Toniatti, Carlo
Published in The journal of gene medicine (01.10.2007)
Published in The journal of gene medicine (01.10.2007)
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Journal Article
Site-Specific Integration Mediated by a Hybrid Adenovirus/Adeno-associated Virus Vector
Recchia, Alessandra, Parks, Robin J., Lamartina, Stefania, Toniatti, Carlo, Pieroni, Luisa, Palombo, Fabio, Ciliberto, Gennaro, Graham, Frank L., Cortese, Riccardo, La Monica, Nicola, Colloca, Stefano
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.1999)
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Lipofection of Purified Adeno-Associated Virus Rep68 Protein: toward a Chromosome-Targeting Nonviral Particle
Lamartina, S, Roscilli, G, Rinaudo, D, Delmastro, P, Toniatti, C
Published in Journal of Virology (01.09.1998)
Published in Journal of Virology (01.09.1998)
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Abstract 685: PARP inhibitor MK-4827 is synthetic lethal for tumors with homologous recombination defects associated with ATM-deficiency, PTEN-deletion and microsatellite instability (MSI)
Roscilli, Giuseppe, Gavory, Gerald, Lamartina, Stefania, Marra, Emanuele, Dolinski, Brian, Williams, Sybil, Elbi, Cem, Jones, Philip, Carpenter, Christopher L., Toniatti, Carlo
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Stringent control of gene expression in vivo by using novel doxycycline-dependent trans-activators
Lamartina, Stefania, Roscilli, Giuseppe, Rinaudo, Cira Daniela, Sporeno, Elisabetta, Silvi, Luisa, Hillen, Wolfgang, Bujard, Hermann, Cortese, Riccardo, Ciliberto, Gennaro, Toniatti, Carlo
Published in Human gene therapy (20.01.2002)
Published in Human gene therapy (20.01.2002)
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Journal Article
Discovery of 2-{4-[(3 S )-Piperidin-3-yl]phenyl}-2 H -indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in BRCA-1 and -2 Mutant Tumors
Jones, Philip, Altamura, Sergio, Boueres, Julia, Ferrigno, Federica, Fonsi, Massimiliano, Giomini, Claudia, Lamartina, Stefania, Monteagudo, Edith, Ontoria, Jesus M., Orsale, Maria Vittoria, Palumbi, Maria Cecilia, Pesci, Silvia, Roscilli, Giuseppe, Scarpelli, Rita, Schultz-Fademrecht, Carsten, Toniatti, Carlo, Rowley, Michael
Published in Journal of medicinal chemistry (26.11.2009)
Published in Journal of medicinal chemistry (26.11.2009)
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Journal Article
Construction of an rtTA2 -m2/tts -Based Transcription Regulatory Switch That Displays No Basal Activity, Good Inducibility, and High Responsiveness to Doxycycline in Mice and Non-Human Primates
Lamartina, Stefania, Silvi, Luisa, Roscilli, Giuseppe, Casimiro, Danilo, Simon, Adam J, Davies, Mary-Ellen, Shiver, John W, Rinaudo, Cira Daniela, Zampaglione, Immacolata, Fattori, Elena, Colloca, Stefano, Gonzalez Paz, Odalys, Laufer, Ralph, Bujard, Hermann, Cortese, Riccardo, Ciliberto, Gennaro, Toniatti, Carlo
Published in Molecular therapy (01.02.2003)
Published in Molecular therapy (01.02.2003)
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Journal Article
Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor
Kinose, Fumi, Roscilli, Giuseppe, Lamartina, Stefania, Anderson, Kenneth D, Bonelli, Fabio, Spence, Stanley G, Ciliberto, Gennaro, Vogt, Thomas F, Holder, Daniel J, Toniatti, Carlo, Thut, Catherine J
Published in Molecular vision (27.05.2005)
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Published in Molecular vision (27.05.2005)
Journal Article
Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer
Rota, Rossella, Riccioni, Teresa, Zaccarini, Marco, Lamartina, Stefania, Gallo, Anna Del, Fusco, Angelo, Kovesdi, Imre, Balestrazzi, Emilio, Abeni, Damiano C., Ali, Robin R., Capogrossi, Maurizio C.
Published in The journal of gene medicine (01.09.2004)
Published in The journal of gene medicine (01.09.2004)
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Journal Article
Long-Term and Tight Control of Gene Expression in Mouse Skeletal Muscle by a New Hybrid Human Transcription Factor
Roscilli, Giuseppe, Rinaudo, Cira Daniela, Cimino, Monica, Sporeno, Elisabetta, Lamartina, Stefania, Ciliberto, Gennaro, Toniatti, Carlo
Published in Molecular therapy (01.11.2002)
Published in Molecular therapy (01.11.2002)
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βMinor-globin messenger RNA accumulation in reticulocytes governs improved erythropoiesis in β thalassemic mice after erythropoietin complementary DNA electrotransfer in muscles
Samakoglu, Selda, Fattori, Elena, Lamartina, Stefania, Toniatti, Carlo, Stockholm, Daniel, Heard, Jean Michel, Bohl, Delphine
Published in Blood (15.04.2001)
Published in Blood (15.04.2001)
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Journal Article
Construction of an rtTA2s-m2/ttskid-Based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and Non-Human primates
Lamartina, Stefania, Silvi, Luisa, Roscilli, Giuseppe, Casimiro, Danilo, Simon, Adam J, Davies, Mary-Ellen, Shiver, John W, Rinaudo, Cira Daniela, Zampaglione, Immacolata, Fattori, Elena, Colloca, Stefano, Paz, Odalys Gonzalez, Laufer, Ralph, Bujard, Hermann, Cortese, Riccardo, Ciliberto, Gennaro, Toniatti, Carlo
Published in Molecular therapy (01.02.2003)
Published in Molecular therapy (01.02.2003)
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