Zanubrutinib or Ibrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia
Brown, Jennifer R., Eichhorst, Barbara, Hillmen, Peter, Jurczak, Wojciech, Kaźmierczak, Maciej, Lamanna, Nicole, O’Brien, Susan M., Tam, Constantine S., Qiu, Lugui, Zhou, Keshu, Simkovic, Martin, Mayer, Jiri, Gillespie-Twardy, Amanda, Ferrajoli, Alessandra, Ganly, Peter S., Weinkove, Robert, Grosicki, Sebastian, Mital, Andrzej, Robak, Tadeusz, Osterborg, Anders, Yimer, Habte A., Salmi, Tommi, Wang, Megan-Der-Yu, Fu, Lina, Li, Jessica, Wu, Kenneth, Cohen, Aileen, Shadman, Mazyar
Published in The New England journal of medicine (26.01.2023)
Published in The New England journal of medicine (26.01.2023)
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Optimal sequencing of ibrutinib, idelalisib, and venetoclax in chronic lymphocytic leukemia: results from a multicenter study of 683 patients
Mato, A.R., Hill, B.T., Lamanna, N., Barr, P.M., Ujjani, C.S., Brander, D.M., Howlett, C., Skarbnik, A.P., Cheson, B.D., Zent, C.S., Pu, J.J., Kiselev, P., Foon, K., Lenhart, J., Henick Bachow, S., Winter, A.M., Cruz, A.-L., Claxton, D.F., Goy, A., Daniel, C., Isaac, K., Kennard, K.H., Timlin, C., Fanning, M., Gashonia, L., Yacur, M., Svoboda, J., Schuster, S.J., Nabhan, C.
Published in Annals of oncology (01.05.2017)
Published in Annals of oncology (01.05.2017)
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Zanubrutinib versus ibrutinib in relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma (R/R CLL/SLL): Impact on health‐related quality of life
Eichhorst, B., Lamanna, N., O'Brien, S. M., Tam, C. S., Qiu, L., Yang, K., Wu, K., Salmi, T., Barnes, G., Brown, J. R.
Published in Hematological oncology (01.06.2023)
Published in Hematological oncology (01.06.2023)
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Zanubrutinib safety/tolerability profile and comparison with ibrutinib profile in B‐cell malignancies: Post hoc analysis of a large clinical trial safety database
Brown, J. R., Eichorst, B., Ghia, P., Jurczak, W., Kahl, B. S., Lamanna, N., Robak, T., Shadman, M., Tam, C. S., Qiu, L., Cohen, A., Zhang, M., Salmi, T., Paik, J., Wang, L., Zhang, J., Ma, H., Tedeschi, A.
Published in Hematological oncology (01.06.2023)
Published in Hematological oncology (01.06.2023)
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Phase 1/2 Study of Zilovertamab and Ibrutinib in Mantle Cell Lymphoma (MCL), Chronic Lymphocytic Leukemia (CLL), or Marginal Zone Lymphoma (MZL)
Lee, H., Choi, M., Siddiqi, T., Rhodes, J., Wierda, W., Isufi, I., Tuscano, J., Lamanna, N., Subbiah, S., Koff, J., Leslie, L., Goldenberg, A., Chung, G., Breitmeyer, J., Yazji, S., Shih, T., Wang, M., Jamieson, C., Kipps, T.
Published in Hematological oncology (01.06.2023)
Published in Hematological oncology (01.06.2023)
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MURANO: Final 7 year follow up and retreatment analysis in venetoclax‐rituximab (VenR)‐treated patients with relapsed/refractory chronic lymphocytic leukemia (R/R CLL)
Kater, A. P., Harrup, R., Kipps, T. J., Eichhorst, B., Owen, C. J., Assouline, S., Lamanna, N., Robak, T., Serna, J. d. l., Jaeger, U., Cartron, G., Montillo, M., Mellink, C., Chyla, B., Thadani‐Mulero, M., Lefebure, M., Jiang, Y., Millen, R., Boyer, M., Seymour, J. F.
Published in Hematological oncology (01.06.2023)
Published in Hematological oncology (01.06.2023)
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Journal Article
COMPARISON OF BLEEDING-RELATED EVENTS IN PATIENTS WHO RECEIVED PIRTOBRUTINIB WITH AND WITHOUT ANTITHROMBOTIC AGENTS
Lamanna, N, Tam, CS, Jurczak, W, Kontos, A, Konig, H, Ruppert, AS, Tsai, DE, Scheliga, AAS
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
Published in Hematology, Transfusion and Cell Therapy (01.10.2023)
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PIRTOBRUTINIB (LOXO‐305), A NEXT GENERATION HIGHLY SELECTIVE NON‐COVALENT BTK INHIBITOR IN PREVIOUSLY TREATED RICHTER TRANSFORMATION: RESULTS FROM THE PHASE 1/2 BRUIN STUDY
Jurczak, W., Shah, N. N., Lamanna, N., Eyre, T. A., Woyach, J., Lech‐Maranda, E., Wierda, W. G., Lewis, D., Thompson, M. C., Wang, D., Yin, M., Balbas, M., Nair, B. C., Zhu, E. Y., Tsai, D. E., Ku, N. C., Coombs, C. C., Mato, A. R.
Published in Hematological oncology (01.06.2021)
Published in Hematological oncology (01.06.2021)
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P663: HEALTH‐RELATED QUALITY OF LIFE OUTCOMES ASSOCIATED WITH ZANUBRUTINIB VS IBRUTINIB MONOTHERAPY IN PATIENTS WITH RELAPSED/REFRACTORY (RR) CLL/SLL: RESULTS FROM THE RANDOMIZED PHASE 3 ALPINE TRIAL
Hillmen, P., Brown, J., Lamanna, N., O'Brien, S., Tam, C., Qiu, L., Yang, K., Barnes, G., Wu, K., Salmi, T., Eichhorst, B.
Published in HemaSphere (01.06.2022)
Published in HemaSphere (01.06.2022)
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EFFECT OF DOSE MODIFICATIONS ON RESPONSE TO DUVELISIB IN PATIENTS WITH RELAPSED/REFRACTORY CLL/SLL IN THE DUO TRIAL
Ghia, P., Flinn, I.W., Lamanna, N., Montillo, M., Illés, Á., Etienne, G., Delgado, J., Kuss, B.J., Tam, C.S., Offner, F., Bosch, F., Davids, M.S., Jäger, U., Cymbalista, F., Weaver, D.T., Lustgarten, S., Youssoufian, H., Stilgenbauer, S.
Published in Hematological oncology (01.06.2019)
Published in Hematological oncology (01.06.2019)
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P671: TREATMENT SEQUENCES AND OUTCOMES OF PATIENTS WITH CLL TREATED WITH TARGETED AGENTS IN REAL‐WORLD SETTINGS
Mato, A. R., Manzoor, B. S., Coombs, C. C., Lamanna, N., Tuncer, H. H., Brown, J. R., Roeker, L. E., Shadman, M., Allan, J. N., Ujjani, C., Eichhorst, B., Leslie, L., Fleury, I., Alhasani, H., Rhodes, J., Hill, B. T., Barr, P. M., Skarbnik, A., Davids, M. S., Bannerji, R., Fuldeore, M., Lansigan, F., Schuh, A., Pearson, L., Fox, C. P., Pivneva, I., Popadic, L., Guerin, A., Eyre, T. A.
Published in HemaSphere (01.06.2022)
Published in HemaSphere (01.06.2022)
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A PHASE 2 STUDY TO ASSESS THE SAFETY AND EFFICACY OF UMBRALISIB IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) WHO ARE INTOLERANT TO PRIOR BTK OR PI3K DELTA INHIBITOR THERAPY
Mato, A.R., Schuster, S.J., Lamanna, N., Pagel, J.M., Flinn, I.W., Barrientos, J., Reeves, J.A., Cheson, B.D., Barr, P.M., Kambhampati, S., Lansigan, F., Pu, J.J., Skarbnik, A., Fonseca, G., Dorsey, C., LaRatta, N.M., Weissbrot, H., Svoboda, J., Luning Prak, E.T., Tsao, P., Sitlinger, A., Paskalis, D., Sportelli, P., Miskin, H.P., Weiss, M.S., Brander, D.M.
Published in Hematological oncology (01.06.2019)
Published in Hematological oncology (01.06.2019)
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P1101: PIRTOBRUTINIB, A HIGHLY SELECTIVE, NON‐COVALENT (REVERSIBLE) BTK INHIBITOR IN PREVIOUSLY TREATED MANTLE CELL LYMPHOMA: UPDATED RESULTS FROM THE PHASE 1/2 BRUIN STUDY
Eyre, T. A., Wang, M. L., Shah, N. N., Alencar, A. J., Gerson, J. N., Patel, M. R., Fakhri, B., Vandenberghe, E., Jurczak, W., Tan, X. N., Lewis, K. L., Fenske, T., Wang, Y., Coombs, C. C., Flinn, I., Lewis, D., Le Gouill, S., Gandhi, M., Chay, C., Palomba, M. L., Woyach, J. A., Pagel, J. M., Lamanna, N., Sharman, J. P., Andorsky, D. J., Cohen, J. B., Barve, M. A., Ghia, P., Yin, M., Zinzani, P. L., Ujjani, C., Koh, Y., Izutsu, K., Lech‐Maranda, E., Kherani, J., Tam, C., Sundaram, S., Nair, B., Tsai, D. E., Balbas, M., Mato, A. R., Cheah, C. Y.
Published in HemaSphere (23.06.2022)
Published in HemaSphere (23.06.2022)
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S147: PIRTOBRUTINIB, A HIGHLY SELECTIVE, NON‐COVALENT (REVERSIBLE) BTK INHIBITOR IN PREVIOUSLY TREATED CLL/SLL: UPDATED RESULTS FROM THE PHASE 1/2 BRUIN STUDY
Mato, A. R., Pagel, J. M., Coombs, C. C., Shah, N. N., Lamanna, N., Munir, T., Lech‐Maranda, E., Eyre, T. A., Woyach, J. A., Wierda, W. G., Cheah, C. Y., Cohen, J. B., Roeker, L. E., Patel, M. R., Fakhri, B., Barve, M. A., Tam, C., Lewis, D., Gerson, J. N., Alencar, A. J., Ujjani, C., Flinn, I., Sundaram, S., Ma, S., Jagadeesh, D., Rhodes, J., Taylor, J., Abdel‐Wahab, O., Ghia, P., Schuster, S. J., Wang, D., Nair, B., Zhu, E., Tsai, D. E., Davids, M. S., Brown, J. R., Jurczak, W.
Published in HemaSphere (01.06.2022)
Published in HemaSphere (01.06.2022)
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Neuroimaging revealed long-lasting glucose metabolism changes to morphine withdrawal in rats pretreated with the cannabinoid agonist CP-55,940 during periadolescence
Lamanna-Rama, N., MacDowell, K.S., López, G., Leza, J.C., Desco, M., Ambrosio, E., Soto-Montenegro, M.L.
Published in European neuropsychopharmacology (01.04.2023)
Published in European neuropsychopharmacology (01.04.2023)
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PCN103 Variation in Health-Related Quality of Life by Age Among Patients With Chronic Lymphocytic Leukemia
Pashos, C.L, Flowers, C.R, Weiss, M, Lamanna, N, Farber, C, Kipps, T.J, Lerner, S, Kay, N, Sharman, J, Grinblatt, D.L, Flinn, I.W, Kozloff, M.F, Swern, A.S, Khan, Z, Street, T.K, Sullivan, K.A, Harding, G, Keating, M.J
Published in Value in health (01.06.2012)
Published in Value in health (01.06.2012)
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Second interim analysis of a phase 3 study evaluating idelalisib and rituximab for relapsed chronic lymphocytic leukemia
Ghia, P, Coutre, S.E, Furman, R.R, Sharman, J.P, Cheson, B.D, Pagel, J.M, Hillmen, P, Barrientos, J.C, Zelenetz, A.D, Kipps, T.J, Flinn, I.W, Eradat, H.A, Lamanna, N, Coiffier, B, Pettitt, A, Li, X, Jahn, T.M, O'Brien, S.M, Hallek, M.J
Published in Journal of geriatric oncology (01.10.2014)
Published in Journal of geriatric oncology (01.10.2014)
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Journal Article
Zanubrutinib Versus Ibrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma: Interim Analysis of a Randomized Phase III Trial
Hillmen, Peter, Eichhorst, Barbara, Brown, Jennifer R, Lamanna, Nicole, O'Brien, Susan M, Tam, Constantine S, Qiu, Lugui, Kazmierczak, Maciej, Zhou, Keshu, Šimkovič, Martin, Mayer, Jiří, Gillespie-Twardy, Amanda, Shadman, Mazyar, Ferrajoli, Alessandra, Ganly, Peter S, Weinkove, Robert, Grosicki, Sebastian, Mital, Andrzej, Robak, Tadeusz, Österborg, Anders, Yimer, Habte A, Salmi, Tommi, Ji, Meng, Yecies, Jessica, Idoine, Adam, Wu, Kenneth, Huang, Jane, Jurczak, Wojciech
Published in Journal of clinical oncology (10.02.2023)
Published in Journal of clinical oncology (10.02.2023)
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17th International Conference on Malignant Lymphoma, Palazzo dei Congressi, Lugano, Switzerland, 13 - 17 June, 2023
Eichhorst, B, Lamanna, N, O'Brien, S M, Tam, C S, Qiu, L, Yang, K, Wu, K, Salmi, T, Barnes, G, Brown, J R
Published in Hematological oncology (01.06.2023)
Published in Hematological oncology (01.06.2023)
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