CHIP Protects from the Neurotoxicity of Expanded and Wild-type Ataxin-1 and Promotes Their Ubiquitination and Degradation
Al-Ramahi, Ismael, Lam, Yung C., Chen, Hung-Kai, de Gouyon, Beatrice, Zhang, Minghang, Pérez, Alma M., Branco, Joana, de Haro, Maria, Patterson, Cam, Zoghbi, Huda Y., Botas, Juan
Published in The Journal of biological chemistry (08.09.2006)
Published in The Journal of biological chemistry (08.09.2006)
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Journal Article
ATAXIN-1 Interacts with the Repressor Capicua in Its Native Complex to Cause SCA1 Neuropathology
Lam, Yung C., Bowman, Aaron B., Jafar-Nejad, Paymaan, Lim, Janghoo, Richman, Ronald, Fryer, John D., Hyun, Eric D., Duvick, Lisa A., Orr, Harry T., Botas, Juan, Zoghbi, Huda Y.
Published in Cell (29.12.2006)
Published in Cell (29.12.2006)
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Journal Article
SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair
Lam, Yung C, Akhter, Shamima, Gu, Peili, Ye, Jing, Poulet, Anaïs, Giraud-Panis, Marie-Josèphe, Bailey, Susan M, Gilson, Eric, Legerski, Randy J, Chang, Sandy
Published in The EMBO journal (07.07.2010)
Published in The EMBO journal (07.07.2010)
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Interaction of Akt-Phosphorylated Ataxin-1 with 14-3-3 Mediates Neurodegeneration in Spinocerebellar Ataxia Type 1
Chen, Hung-Kai, Fernandez-Funez, Pedro, Acevedo, Summer F., Lam, Yung C., Kaytor, Michael D., Fernandez, Michael H., Aitken, Alastair, Skoulakis, Efthimios M.C., Orr, Harry T., Botas, Juan, Zoghbi, Huda Y.
Published in Cell (16.05.2003)
Published in Cell (16.05.2003)
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Journal Article
The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development
Akhter, Shamima, Lam, Yung C., Chang, Sandy, Legerski, Randy J.
Published in Aging cell (01.12.2010)
Published in Aging cell (01.12.2010)
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Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes
Zoghbi, Huda Y, Bowman, Aaron B, Lam, Yung C, Jafar-Nejad, Paymaan, Chen, Hung-Kai, Richman, Ronald, Samaco, Rodney C, Fryer, John D, Kahle, Juliette J, Orr, Harry T
Published in Nature genetics (01.03.2007)
Published in Nature genetics (01.03.2007)
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