C2H2 zinc finger proteins greatly expand the human regulatory lexicon
Najafabadi, Hamed S, Mnaimneh, Sanie, Schmitges, Frank W, Garton, Michael, Lam, Kathy N, Yang, Ally, Albu, Mihai, Weirauch, Matthew T, Radovani, Ernest, Kim, Philip M, Greenblatt, Jack, Frey, Brendan J, Hughes, Timothy R
Published in Nature biotechnology (01.05.2015)
Published in Nature biotechnology (01.05.2015)
Get full text
Journal Article
Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome
Lam, Kathy N., Spanogiannopoulos, Peter, Soto-Perez, Paola, Alexander, Margaret, Nalley, Matthew J., Bisanz, Jordan E., Nayak, Renuka R., Weakley, Allison M., Yu, Feiqiao B., Turnbaugh, Peter J.
Published in Cell reports (Cambridge) (02.11.2021)
Published in Cell reports (Cambridge) (02.11.2021)
Get full text
Journal Article
CRISPR-Cas System of a Prevalent Human Gut Bacterium Reveals Hyper-targeting against Phages in a Human Virome Catalog
Soto-Perez, Paola, Bisanz, Jordan E., Berry, Joel D., Lam, Kathy N., Bondy-Denomy, Joseph, Turnbaugh, Peter J.
Published in Cell host & microbe (11.09.2019)
Published in Cell host & microbe (11.09.2019)
Get full text
Journal Article
Precision Medicine Goes Microscopic: Engineering the Microbiome to Improve Drug Outcomes
Lam, Kathy N., Alexander, Margaret, Turnbaugh, Peter J.
Published in Cell host & microbe (10.07.2019)
Published in Cell host & microbe (10.07.2019)
Get full text
Journal Article
Evaluation of a pooled strategy for high-throughput sequencing of cosmid clones from metagenomic libraries
Lam, Kathy N, Hall, Michael W, Engel, Katja, Vey, Gregory, Cheng, Jiujun, Neufeld, Josh D, Charles, Trevor C
Published in PloS one (09.06.2014)
Published in PloS one (09.06.2014)
Get full text
Journal Article
Current and future resources for functional metagenomics
Lam, Kathy N, Cheng, Jiujun, Engel, Katja, Neufeld, Josh D, Charles, Trevor C
Published in Frontiers in microbiology (29.10.2015)
Published in Frontiers in microbiology (29.10.2015)
Get full text
Journal Article
Identification and characterization of the intracellular poly-3-hydroxybutyrate depolymerase enzyme PhaZ of Sinorhizobium meliloti
Trainer, Maria A, Capstick, David, Zachertowska, Alicja, Lam, Kathy N, Clark, Scott R D, Charles, Trevor C
Published in BMC microbiology (27.03.2010)
Published in BMC microbiology (27.03.2010)
Get full text
Journal Article
Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays
Lam, Kathy N., van Bakel, Harm, Cote, Atina G., van der Ven, Anton, Hughes, Timothy R.
Published in Nucleic acids research (01.06.2011)
Published in Nucleic acids research (01.06.2011)
Get full text
Journal Article
Host and gut bacteria share metabolic pathways for anti-cancer drug metabolism
Spanogiannopoulos, Peter, Kyaw, Than S, Guthrie, Ben G H, Bradley, Patrick H, Lee, Joyce V, Melamed, Jonathan, Malig, Ysabella Noelle Amora, Lam, Kathy N, Gempis, Daryll, Sandy, Moriah, Kidder, Wesley, Van Blarigan, Erin L, Atreya, Chloe E, Venook, Alan, Gerona, Roy R, Goga, Andrei, Pollard, Katherine S, Turnbaugh, Peter J
Published in Nature microbiology (01.10.2022)
Published in Nature microbiology (01.10.2022)
Get full text
Journal Article
Biotransformation research advances - 2022 year in review
Khojasteh, S Cyrus, Argikar, Upendra A, Cheruzel, Lionel, Cho, Sungjoon, Crouch, Rachel D, Dhaware, Deepika, Heck, Carley J S, Johnson, Kevin M, Kalgutkar, Amit S, King, Lloyd, Liu, Joyce, Ma, Bin, Maw, Hlaing, Miller, Grover P, Seneviratne, Herana Kamal, Takahashi, Ryan H, Wang, Shuai, Wei, Cong, Jackson, Klarissa D
Published in Drug metabolism reviews (01.11.2023)
Published in Drug metabolism reviews (01.11.2023)
Get more information
Journal Article
A conserved enzyme found in diverse human gut bacteria interferes with anticancer drug efficacy
Kyaw, Than S, Spanogiannopoulos, Peter, Guthrie, Ben Gh, Bradley, Patrick H, Lee, Joyce V, Melamed, Jonathan, Ysabella Noelle Amora Malig, Lam, Kathy N, Gempis, Daryll, Moriah Sandy, Kidder, Wes, Van Blarigan, Erin L, Atreya, Chloe, Venook, Alan, Gerona, Roy R, Goga, Andrei N, Pollard, Katherine S, Turnbaugh, Peter
Published in bioRxiv (07.04.2022)
Published in bioRxiv (07.04.2022)
Get full text
Paper
Illuminating the microbiome's dark matter: a functional genomic toolkit for the study of human gut Actinobacteria
Bisanz, Jordan E, Soto-Perez, Paola, Lam, Kathy N, Bess, Elizabeth N, Haiser, Henry J, Allen-Vercoe, Emma, Rekdal, Vayu M, Balskus, Emily P, Turnbaugh, Peter J
Published in bioRxiv (01.05.2018)
Published in bioRxiv (01.05.2018)
Get full text
Paper