Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets
Adriaenssens, Alice E., Svendsen, Berit, Lam, Brian Y. H., Yeo, Giles S. H., Holst, Jens J., Reimann, Frank, Gribble, Fiona M.
Published in Diabetologia (01.10.2016)
Published in Diabetologia (01.10.2016)
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Journal Article
Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort
Wade, Kaitlin H, Lam, Brian Y H, Melvin, Audrey, Pan, Warren, Corbin, Laura J, Hughes, David A, Rainbow, Kara, Chen, Jian-Hua, Duckett, Katie, Liu, Xiaoming, Mokrosiński, Jacek, Mörseburg, Alexander, Neaves, Sam, Williamson, Alice, Zhang, Chen, Farooqi, I Sadaf, Yeo, Giles S H, Timpson, Nicholas J, O'Rahilly, Stephen
Published in Nature medicine (01.06.2021)
Published in Nature medicine (01.06.2021)
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Journal Article
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells
Yang, Ming, Darwish, Tamana, Larraufie, Pierre, Rimmington, Debra, Cimino, Irene, Goldspink, Deborah A, Jenkins, Benjamin, Koulman, Albert, Brighton, Cheryl A, Ma, Marcella, Lam, Brian Y H, Coll, Anthony P, O'Rahilly, Stephen, Reimann, Frank, Gribble, Fiona M
Published in Scientific reports (28.01.2021)
Published in Scientific reports (28.01.2021)
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Journal Article
Microarray, qPCR, and KCNJ5 Sequencing of Aldosterone-Producing Adenomas Reveal Differences in Genotype and Phenotype between Zona Glomerulosa- and Zona Fasciculata-Like Tumors
Azizan, Elena A. B, Lam, Brian Y. H, Newhouse, Stephen J, Zhou, Junhua, Kuc, Rhoda E, Clarke, Jennifer, Happerfield, Lisa, Marker, Alison, Hoffman, Gary J, Brown, Morris J
Published in The journal of clinical endocrinology and metabolism (01.05.2012)
Published in The journal of clinical endocrinology and metabolism (01.05.2012)
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Journal Article
Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice
Ramos-Pittol, Jose M, Fernandes-Freitas, Isabel, Milona, Alexandra, Manchishi, Stephen M, Rainbow, Kara, Lam, Brian Y H, Tadross, John A, Beucher, Anthony, Colledge, William H, Cebola, Inês, Murphy, Kevin G, Miguel-Aliaga, Irene, Yeo, Giles S H, Dhillo, Waljit S, Owen, Bryn M
Published in Nature communications (29.05.2023)
Published in Nature communications (29.05.2023)
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Journal Article
Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function
Hammerle, Constanze M, Sandovici, Ionel, Brierley, Gemma V, Smith, Nicola M, Zimmer, Warren E, Zvetkova, Ilona, Prosser, Haydn M, Sekita, Yoichi, Lam, Brian Y H, Ma, Marcella, Cooper, Wendy N, Vidal-Puig, Antonio, Ozanne, Susan E, Medina-Gómez, Gema, Constância, Miguel
Published in PLoS genetics (15.10.2020)
Published in PLoS genetics (15.10.2020)
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Journal Article
Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity
Cimino, Irene, Rimmington, Debra, Tung, Y C Loraine, Lawler, Katherine, Larraufie, Pierre, Kay, Richard G, Virtue, Samuel, Lam, Brian Y H, Fagnocchi, Luca, Ma, Marcella K L, Saudek, Vladimir, Zvetkova, Ilona, Vidal-Puig, Antonio, Yeo, Giles S H, Farooqi, I Sadaf, Pospisilik, J Andrew, Gribble, Fiona M, Reimann, Frank, O'Rahilly, Stephen, Coll, Anthony P
Published in Scientific reports (02.09.2021)
Published in Scientific reports (02.09.2021)
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Journal Article
HypoMap-a unified single-cell gene expression atlas of the murine hypothalamus
Steuernagel, Lukas, Lam, Brian Y H, Klemm, Paul, Dowsett, Georgina K C, Bauder, Corinna A, Tadross, John A, Hitschfeld, Tamara Sotelo, Del Rio Martin, Almudena, Chen, Weiyi, de Solis, Alain J, Fenselau, Henning, Davidsen, Peter, Cimino, Irene, Kohnke, Sara N, Rimmington, Debra, Coll, Anthony P, Beyer, Andreas, Yeo, Giles S H, Brüning, Jens C
Published in Nature metabolism (01.10.2022)
Published in Nature metabolism (01.10.2022)
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Journal Article
p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1
Quiñones, Mar, Al-Massadi, Omar, Folgueira, Cintia, Bremser, Stephan, Gallego, Rosalía, Torres-Leal, Leonardo, Haddad-Tóvolli, Roberta, García-Caceres, Cristina, Hernandez-Bautista, Rene, Lam, Brian Y H, Beiroa, Daniel, Sanchez-Rebordelo, Estrella, Senra, Ana, Malagon, Jose A, Valerio, Patricia, Fondevila, Marcos F, Fernø, Johan, Malagon, Maria M, Contreras, Raian, Pfluger, Paul, Brüning, Jens C, Yeo, Giles, Tschöp, Matthias, Diéguez, Carlos, López, Miguel, Claret, Marc, Kloppenburg, Peter, Sabio, Guadalupe, Nogueiras, Ruben
Published in Nature communications (24.08.2018)
Published in Nature communications (24.08.2018)
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Journal Article
Neurochemical Characterization of Brainstem Pro-Opiomelanocortin Cells
Georgescu, Teodora, Lyons, David, Doslikova, Barbora, Garcia, Ana Paula, Marston, Oliver, Burke, Luke K, Chianese, Raffaella, Lam, Brian Y H, Yeo, Giles S H, Rochford, Justin J, Garfield, Alastair S, Heisler, Lora K
Published in Endocrinology (Philadelphia) (01.04.2020)
Published in Endocrinology (Philadelphia) (01.04.2020)
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Journal Article
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization
Gumy, Laura F, Yeo, Giles S H, Tung, Yi-Chun Loraine, Zivraj, Krishna H, Willis, Dianna, Coppola, Giovanni, Lam, Brian Y H, Twiss, Jeffery L, Holt, Christine E, Fawcett, James W
Published in RNA (Cambridge) (01.01.2011)
Published in RNA (Cambridge) (01.01.2011)
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Journal Article
MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity, and Glucose Intolerance
Al-Massadi, Omar, Quiñones, Mar, Clasadonte, Jerome, Hernandez-Bautista, René, Romero-Picó, Amparo, Folgueira, Cintia, Morgan, Donald A, Kalló, Imre, Heras, Violeta, Senra, Ana, Funderburk, Samuel C, Krashes, Michael J, Souto, Yara, Fidalgo, Miguel, Luquet, Serge, Chee, Melissa J, Imbernon, Monica, Beiroa, Daniel, García-Caballero, Lucía, Gallego, Rosalia, Lam, Brian Y H, Yeo, Giles, Lopez, Miguel, Liposits, Zsolt, Rahmouni, Kamal, Prevot, Vincent, Dieguez, Carlos, Nogueiras, Ruben
Published in Diabetes (New York, N.Y.) (01.12.2019)
Published in Diabetes (New York, N.Y.) (01.12.2019)
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Journal Article
Selective rab11 transport and the intrinsic regenerative ability of CNS axons
Koseki, Hiroaki, Donegá, Matteo, Lam, Brian Yh, Petrova, Veselina, van Erp, Susan, Yeo, Giles Sh, Kwok, Jessica Cf, Ffrench-Constant, Charles, Eva, Richard, Fawcett, James W
Published in eLife (08.08.2017)
Published in eLife (08.08.2017)
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Journal Article
Fetal and trophoblast PI3K p110α have distinct roles in regulating resource supply to the growing fetus in mice
López-Tello, Jorge, Pérez-García, Vicente, Khaira, Jaspreet, Kusinski, Laura C, Cooper, Wendy N, Andreani, Adam, Grant, Imogen, Fernández de Liger, Edurne, Lam, Brian Yh, Hemberger, Myriam, Sandovici, Ionel, Constancia, Miguel, Sferruzzi-Perri, Amanda N
Published in eLife (26.06.2019)
Published in eLife (26.06.2019)
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Journal Article
Human embryonic genome activation initiates at the one-cell stage
Asami, Maki, Lam, Brian Y.H., Ma, Marcella K., Rainbow, Kara, Braun, Stefanie, VerMilyea, Matthew D., Yeo, Giles S.H., Perry, Anthony C.F.
Published in Cell stem cell (03.02.2022)
Published in Cell stem cell (03.02.2022)
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Journal Article
The vagus nerve mediates the physiological but not pharmacological effects of PYY3-36 on food intake
Alonso, Aldara Martin, Cork, Simon C., Phuah, Phyllis, Hansen, Benjamin, Norton, Mariana, Cheng, Sijing, Xu, Xiang, Suba, Kinga, Ma, Yue, Dowsett, Georgina KC, Tadross, John A., Lam, Brian YH, Yeo, Giles SH, Herzog, Herbert, Bloom, Stephen R., Arnold, Myrtha, Distaso, Walter, Murphy, Kevin G., Salem, Victoria
Published in Molecular metabolism (Germany) (01.03.2024)
Published in Molecular metabolism (Germany) (01.03.2024)
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Journal Article
DEFLATE compression algorithm corrects for overestimation of phylogenetic diversity by Grantham approach to single-nucleotide polymorphism classification
Schlosberg, Arran, Lam, Brian Y H, Yeo, Giles S H, Clifton-Bligh, Roderick J
Published in International journal of molecular sciences (13.05.2014)
Published in International journal of molecular sciences (13.05.2014)
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Journal Article
The initiation of mammalian embryonic transcription: to begin at the beginning
Perry, Anthony C.F., Asami, Maki, Lam, Brian Y.H., Yeo, Giles S.H.
Published in Trends in cell biology (01.05.2023)
Published in Trends in cell biology (01.05.2023)
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Journal Article
The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
Sandovici, Ionel, Georgopoulou, Aikaterini, Pérez-García, Vicente, Hufnagel, Antonia, López-Tello, Jorge, Lam, Brian Y.H., Schiefer, Samira N., Gaudreau, Chelsea, Santos, Fátima, Hoelle, Katharina, Yeo, Giles S.H., Burling, Keith, Reiterer, Moritz, Fowden, Abigail L., Burton, Graham J., Branco, Cristina M., Sferruzzi-Perri, Amanda N., Constância, Miguel
Published in Developmental cell (10.01.2022)
Published in Developmental cell (10.01.2022)
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Journal Article
Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet
Nus, Meritxell, Sage, Andrew P, Lu, Yuning, Masters, Leanne, Lam, Brian Y H, Newland, Stephen, Weller, Sandra, Tsiantoulas, Dimitrios, Raffort, Juliette, Marcus, Damiënne, Finigan, Alison, Kitt, Lauren, Figg, Nichola, Schirmbeck, Reinhold, Kneilling, Manfred, Yeo, Giles S H, Binder, Christoph J, de la Pompa, José Luis, Mallat, Ziad
Published in Nature medicine (01.05.2017)
Published in Nature medicine (01.05.2017)
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Journal Article