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Published in Clinical cancer research (01.10.2017)
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Hyman, David M., Piha-Paul, Sarina A., Won, Helen, Rodon, Jordi, Saura, Cristina, Shapiro, Geoffrey I., Juric, Dejan, Quinn, David I., Moreno, Victor, Doger, Bernard, Mayer, Ingrid A., Boni, Valentina, Calvo, Emiliano, Loi, Sherene, Lockhart, Albert C., Erinjeri, Joseph P., Scaltriti, Maurizio, Ulaner, Gary A., Patel, Juber, Tang, Jiabin, Beer, Hannah, Selcuklu, S. Duygu, Hanrahan, Aphrothiti J., Bouvier, Nancy, Melcer, Myra, Murali, Rajmohan, Schram, Alison M., Smyth, Lillian M., Jhaveri, Komal, Li, Bob T., Drilon, Alexander, Harding, James J., Iyer, Gopa, Taylor, Barry S., Berger, Michael F., Cutler Jr, Richard E., Xu, Feng, Butturini, Anna, Eli, Lisa D., Mann, Grace, Farrell, Cynthia, Lalani, Alshad S., Bryce, Richard P., Arteaga, Carlos L., Meric-Bernstam, Funda, Baselga, José, Solit, David B.
Published in Nature (London) (08.02.2018)
Published in Nature (London) (08.02.2018)
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Hanker, Ariella B., Brown, Benjamin P., Meiler, Jens, Marín, Arnaldo, Jayanthan, Harikrishna S., Ye, Dan, Lin, Chang-Ching, Akamatsu, Hiroaki, Lee, Kyung-Min, Chatterjee, Sumanta, Sudhan, Dhivya R., Servetto, Alberto, Brewer, Monica Red, Koch, James P., Sheehan, Jonathan H., He, Jie, Lalani, Alshad S., Arteaga, Carlos L.
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Published in Cancer cell (09.08.2021)
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Published in Cancer research (Chicago, Ill.) (2013)
Published in Cancer research (Chicago, Ill.) (2013)
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Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2 +ve breast cancer metastasis
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Published in PloS one (13.11.2014)
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Published in Cancer discovery (01.05.2020)
Published in Cancer discovery (01.05.2020)
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Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2 -Mutated Breast Cancer
Collins, Denis M, Conlon, Neil T, Kannan, Srinivasaraghavan, Verma, Chandra S, Eli, Lisa D, Lalani, Alshad S, Crown, John
Published in Cancers (28.05.2019)
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HDAC inhibitors enhance neratinib activity and when combined enhance the actions of an anti-PD-1 immunomodulatory antibody in vivo
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Published in Oncotarget (27.10.2017)
Published in Oncotarget (27.10.2017)
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Use of Ex Vivo Patient-Derived Tumor Organotypic Spheroids to Identify Combination Therapies for HER2 Mutant Non-Small Cell Lung Cancer
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Published in Clinical cancer research (15.05.2020)
Published in Clinical cancer research (15.05.2020)
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Neratinib augments the lethality of [regorafenib + sildenafil]
Booth, Laurence, Roberts, Jane L., Rais, Rumeesa, Cutler, Richard E., Diala, Irmina, Lalani, Alshad S., Hancock, John F., Poklepovic, Andrew, Dent, Paul
Published in Journal of cellular physiology (01.04.2019)
Published in Journal of cellular physiology (01.04.2019)
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Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2)
Cocco, Emiliano, Javier Carmona, F, Razavi, Pedram, Won, Helen H, Cai, Yanyan, Rossi, Valentina, Chan, Carmen, Cownie, James, Soong, Joanne, Toska, Eneda, Shifman, Sophie G, Sarotto, Ivana, Savas, Peter, Wick, Michael J, Papadopoulos, Kyriakos P, Moriarty, Alyssa, Cutler, Jr, Richard E, Avogadri-Connors, Francesca, Lalani, Alshad S, Bryce, Richard P, Chandarlapaty, Sarat, Hyman, David M, Solit, David B, Boni, Valentina, Loi, Sherene, Baselga, José, Berger, Michael F, Montemurro, Filippo, Scaltriti, Maurizio
Published in Science signaling (09.10.2018)
Published in Science signaling (09.10.2018)
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Combined Blockade of Activating ERBB2 Mutations and ER Results in Synthetic Lethality of ER+/HER2 Mutant Breast Cancer
Croessmann, Sarah, Formisano, Luigi, Kinch, Lisa N, Gonzalez-Ericsson, Paula I, Sudhan, Dhivya R, Nagy, Rebecca J, Mathew, Aju, Bernicker, Eric H, Cristofanilli, Massimo, He, Jie, Cutler, Jr, Richard E, Lalani, Alshad S, Miller, Vincent A, Lanman, Richard B, Grishin, Nick V, Arteaga, Carlos L
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Published in Clinical cancer research (01.01.2019)
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Neratinib and entinostat combine to rapidly reduce the expression of K-RAS, N-RAS, Gαq and Gα11 and kill uveal melanoma cells
Booth, Laurence, Roberts, Jane L., Sander, Cindy, Lalani, Alshad S., Kirkwood, John M., Hancock, John F., Poklepovic, Andrew, Dent, Paul
Published in Cancer biology & therapy (04.05.2019)
Published in Cancer biology & therapy (04.05.2019)
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The Phase II MutHER Study of Neratinib Alone and in Combination with Fulvestrant in HER2-Mutated, Non-amplified Metastatic Breast Cancer
Ma, Cynthia X, Luo, Jingqin, Freedman, Rachel A, Pluard, Timothy J, Nangia, Julie R, Lu, Janice, Valdez-Albini, Frances, Cobleigh, Melody, Jones, Jason M, Lin, Nancy U, Winer, Eric P, Marcom, P Kelly, Thomas, Shana, Anderson, Jill, Haas, Brittney, Bucheit, Leslie, Bryce, Richard, Lalani, Alshad S, Carey, Lisa A, Goetz, Matthew P, Gao, Feng, Kimmick, Gretchen, Pegram, Mark D, Ellis, Matthew J, Bose, Ron
Published in Clinical cancer research (01.04.2022)
Published in Clinical cancer research (01.04.2022)
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Neratinib and entinostat combine to rapidly reduce the expression of K-RAS, N-RAS, Gα q and Gα 11 and kill uveal melanoma cells
Booth, Laurence, Roberts, Jane L, Sander, Cindy, Lalani, Alshad S, Kirkwood, John M, Hancock, John F, Poklepovic, Andrew, Dent, Paul
Published in Cancer biology & therapy (04.05.2019)
Published in Cancer biology & therapy (04.05.2019)
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