Safety and clinical activity of BMS-986365 (CC-94676), a dual androgen receptor ligand-directed degrader and antagonist, in heavily pretreated patients with metastatic castration-resistant prostate cancer
Rathkopf, D.E., Patel, M.R., Choudhury, A.D., Rasco, D., Lakhani, N., Hawley, J.E., Srinivas, S., Aparicio, A., Narayan, V., Runcie, K.D., Emamekhoo, H., Reichert, Z.R., Nguyen, M.H., Wells, A.L., Kandimalla, R., Liu, C., Suryawanshi, S., Han, J., Wu, J., Arora, V.K., Pourdehnad, M., Armstrong, A.J.
Published in Annals of oncology (16.09.2024)
Published in Annals of oncology (16.09.2024)
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A first-in-human study of the anti-LAG-3 antibody favezelimab plus pembrolizumab in previously treated, advanced microsatellite stable colorectal cancer
Garralda, E., Sukari, A., Lakhani, N.J., Patnaik, A., Lou, Y., Im, S.-A., Golan, T., Geva, R., Wermke, M., de Miguel, M., Palcza, J., Jha, S., Chaney, M., Abraham, A.K., Healy, J., Falchook, G.S.
Published in ESMO open (01.12.2022)
Published in ESMO open (01.12.2022)
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Preliminary results of pamiparib (BGB-290), a PARP1/2 inhibitor, in combination with temozolomide (TMZ) in patients (pts) with locally advanced or metastatic solid tumors
Johnson, M, Galsky, M, Barve, M, Goel, S, Park, H, Du, B, Mu, S, Ramakrishnan, V, Wood, K, Wang, V, Lakhani, N
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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A first-in-human phase I study of the PD-1 inhibitor, retifanlimab (INCMGA00012), in patients with advanced solid tumors (POD1UM-101)
Lakhani, N., Cosman, R., Banerji, U., Rasco, D., Tomaszewska-Kiecana, M., Garralda, E., Kornacki, D., Li, J., Tian, C., Bourayou, N., Powderly, J.
Published in ESMO open (01.04.2024)
Published in ESMO open (01.04.2024)
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Phase I, first-in-human study of MSC-1 (AZD0171), a humanized anti-leukemia inhibitory factor monoclonal antibody, for advanced solid tumors
Borazanci, E., Schram, A.M., Garralda, E., Brana, I., Vieito Villar, M., Spreafico, A., Oliva, M., Lakhani, N.J., Hoffman, K., Hallett, R.M., Maetzel, D., Hua, F., Hilbert, J., Giblin, P., Anido, J., Kelly, A., Vickers, P.J., Wasserman, R., Seoane, J., Siu, L.L., Hyman, D.M., Hoff, D.V., Tabernero, J.
Published in ESMO open (01.08.2022)
Published in ESMO open (01.08.2022)
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Detection and clearance of RET variants in plasma cell free DNA (cfDNA) from patients (pts) treated with LOXO-292
Besse, B., Subbiah, V., Drilon, A., Shah, M., Wirth, L.J., Bauer, T.M., Velcheti, V., Lakhani, N., Boni, V., Solomon, B.J., Johnson, M., Park, K., Patel, J., Cabanillas, M.E., Sherman, E., Zhu, E., Gordon, K., Ebata, K., Tuch, B., Oxnard, G.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Fingerprinting and molecular comparison among two parental strains of Trichoderma spp. and their corresponding fusants produced by protoplast fusion
Lakhani, Hardik N., Vakharia, Dinesh N., Hassan, Mohamed M., Eissa, Ragaa A.
Published in Biotechnology, biotechnological equipment (01.11.2016)
Published in Biotechnology, biotechnological equipment (01.11.2016)
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Clinical profile of severe generalised tetanus patients
Shastri, Minal, Gupta, Rajdeep, Lakhani, Neet, Patel, Harsh, Samarth Thakkar, Samarth Thakkar, Kansara, Tikal Mukesh
Published in Australasian Medical Journal (Online) (01.01.2017)
Published in Australasian Medical Journal (Online) (01.01.2017)
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Efficacy of Selpercatinib in RET-Altered Thyroid Cancers
Wirth, Lori J, Sherman, Eric, Robinson, Bruce, Solomon, Benjamin, Kang, Hyunseok, Lorch, Jochen, Worden, Francis, Brose, Marcia, Patel, Jyoti, Leboulleux, Sophie, Godbert, Yann, Barlesi, Fabrice, Morris, John C, Owonikoko, Taofeek K, Tan, Daniel S.W, Gautschi, Oliver, Weiss, Jared, de la Fouchardière, Christelle, Burkard, Mark E, Laskin, Janessa, Taylor, Matthew H, Kroiss, Matthias, Medioni, Jacques, Goldman, Jonathan W, Bauer, Todd M, Levy, Benjamin, Zhu, Viola W, Lakhani, Nehal, Moreno, Victor, Ebata, Kevin, Nguyen, Michele, Heirich, Dana, Zhu, Edward Y, Huang, Xin, Yang, Luxi, Kherani, Jennifer, Rothenberg, S. Michael, Drilon, Alexander, Subbiah, Vivek, Shah, Manisha H, Cabanillas, Maria E
Published in The New England journal of medicine (27.08.2020)
Published in The New England journal of medicine (27.08.2020)
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Increased frequency of venous thromboembolism with the combination of docetaxel and thalidomide in patients with metastatic androgen-independent prostate cancer
Horne, 3rd, McDonald K, Figg, William D, Arlen, Phil, Gulley, James, Parker, Catherine, Lakhani, Nehal, Parnes, Howard, Dahut, William L
Published in Pharmacotherapy (01.03.2003)
Published in Pharmacotherapy (01.03.2003)
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165 (PB153): NEXUS-01, a phase 1 study of LY4052031, an antibody-drug conjugate targeting Nectin-4 in participants with advanced or metastatic urothelial carcinoma or other solid tumors (Trial in Progress)
Baldini, C., Patnaik, A., Lakhani, N., Call, J., Galsky, M., Garmezy, B., Wei, A., Carter, L., Powles, T., Siefker-Radtke, A., O’Donnell, P.H., Kitano, S., Castellano, D.E., Shinde, R., Joshua, A.M., Balbas, M., Han, H., Chang, A.E., Gao, X., Iyer, G.
Published in European journal of cancer (1990) (01.10.2024)
Published in European journal of cancer (1990) (01.10.2024)
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Establishment and characterization of a panel of BRAFV600E colorectal XPDX models from patients with acquired resistance to targeted therapies
Moriarty, A., Flores, J., Peskin, A., Lynch, M., Papadopoulos, K., Lakhani, N., Sharma, M., Drengler, R., Szender, J., Rasco, D., Patnaik, A., Bucheit, A., Wick, M.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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663P Safety and preliminary efficacy of the KRAS G12C Inhibitor MK-1084 in solid tumors and in combination with pembrolizumab in NSCLC
Rojas, C., Lugowska, I., Juergens, R., Sacher, A., Weindler, S., Sendur, M.A.N., Dziadziuszko, R., Pal, A., Castanon Alvarez, E., Ahern, E.S., Lakhani, N., Chen, L-C., Jemielita, T., Choi, Y.S., Stathis, A.
Published in Annals of oncology (01.10.2023)
Published in Annals of oncology (01.10.2023)
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660MO First-in-human study of SGN-B7H4V, a B7-H4-directed vedotin ADC, in patients with advanced solid tumors: Preliminary results of a phase I study (SGNB7H4V-001)
Perez, C.A., Henry, J.T., Lakhani, N., Call, J.A., Hamilton, E.P., Colon-Otero, G., Diamond, J.R., O’Neil, B., Kalyan, A., Sonpavde, G.P., Moreno Candilejo, I., Awan, A.A., Fontana, E., Xu, P., Zhang, F., Nazarenko, N., Patnaik, A.
Published in Annals of oncology (01.10.2023)
Published in Annals of oncology (01.10.2023)
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400P Phase I study of fianlimab, a human lymphocyte activation gene-3 (LAG-3) monoclonal antibody, in combination with cemiplimab in advanced melanoma (mel)
Hamid, O., Weise, A., Kim, T.M., Mckean, M., Lakhani, N., Crown, J., Kaczmar, J., Papadopoulos, K., Chen, S., Mani, J., Jankovic, V., Kroog, G., Sims, T., Lowy, I., Gullo, G.
Published in Annals of oncology (01.11.2022)
Published in Annals of oncology (01.11.2022)
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Efficacy signals, long-term exposure and safety data from a phase 1–2 study of a cell-penetrating peptide antagonist of CEBPβ, a novel target, in patients (pts) with refractory solid tumors
Fontana, E., Williams, A., Falchook, G., Lakhani, N., Evans, T.R.J., Gondi, V., Iwamoto, F., McKean, M., Symeonides, S., Butowski, N., McLaren, A., Henry, J., Buerki, R., Rotolo, J., Capiaux, G., Michel, R., Kaesshaefer, S., Wiegert, E., Bexon, A.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Identification and molecular characterization of invasive lobular breast cancer models in a panel of 180 breast XPDX models
Flores, J., Moriarty, A., Lizette, F., Lang, A., Rosenthal, A., Papadopoulos, K., Beeram, M., Patnaik, A., Rasco, D., DeBerry, B., Elmi, M., Drengler, R., Hernandez, T., Sharma, M., Lakhani, N., Smith, L., Moreno, V., Calvo, E., Garcia-Foncillas, J., Wick, M.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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SO-31 ASPEN-01: A phase 1 study of ALX148, a CD47 blocker, in combination with trastuzumab, ramucirumab and paclitaxel in patients with second-line HER2-positive advanced gastric or gastroesophageal junction cancer
Chung, H., Lee, K., Kim, W., Gainor, J., Lakhani, N., Chow, L., Messersmith, W., Fanning, P., Squifflet, P., Jin, F., Forgie, A., Wan, H., Pons, J., Randolph, S., LoRusso, P.
Published in Annals of oncology (01.07.2021)
Published in Annals of oncology (01.07.2021)
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A Phase 1 PK/PD Study of ASN003, a novel highly selective BRAF and PI3K inhibitor, in patients with advanced solid tumors
Rasco, D., Sullivan, R., Lakhani, N., Reddy, S., Rao, N., Denis, L., Tolcher, A., Flaherty, K.T.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
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