Development of a Scaleable Synthesis of a Geminal Dimethyl Tertiary Amine as an Inhaled Muscarinic Antagonist for the Treatment of COPD
Dillon, Barry R, Roberts, Dannielle F, Entwistle, David A, Glossop, Paul A, Knight, Craig J, Laity, Daniel A, James, Kim, Praquin, Celine F, Strang, Ross S, Watson, Christine A. L
Published in Organic process research & development (17.02.2012)
Published in Organic process research & development (17.02.2012)
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Convergent Asymmetric Synthesis of Two Complex TRPV1 Antagonists
Butcher, Kenneth J, Denton, Steven M, Field, Stuart E, Gillmore, Adam T, Harbottle, Gareth W, Howard, Roger M, Laity, Daniel A, Ngono, Christian J, Pibworth, Benjamin A
Published in Organic process research & development (16.09.2011)
Published in Organic process research & development (16.09.2011)
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Transition-Metal-Free Synthesis of a Densely Functionalized Benzodioxole Intermediate toward Lotiglipron
Wang, Jimmy, Clarke, James, Badland, Matthew, Broadbelt, Brian, Dow, Louise F., Fenton, Harriet A. M., Laity, Daniel A., Mathew, Jinu S., Rose, Emily K., Tamosiunaite, Neringa, Twiddle, Steven J. R., Walton, Robert
Published in Organic process research & development (19.04.2024)
Published in Organic process research & development (19.04.2024)
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Development of the Synthetic Route to PF-06878031 Part 1: Selective Alkylation Route
Brea, Oriana, Buck, Julia, Carson, Nessa, Derrick, Andrew M., Fussell, Steven J., Gymer, Adam E. S., Hawksworth, Michael, Hopkins, Adam W., Ingram, Heather, Johnson, Rebecca A., Laity, Daniel A., Mathew, Jinu S., Moses, Ian B., Rellegue, James, Rose, Emily K., Twiddle, Steven J. R., West, Adam
Published in Organic process research & development (19.07.2024)
Published in Organic process research & development (19.07.2024)
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Journal Article
Development of the Synthetic Route to PF-06878031 Part 2: Amide Reduction Route
Brown, Maria S., Buck, Julia, Critcher, Douglas J., Derrick, Andrew M., Fenton, Harriet, Fussell, Steven J., Gymer, Adam E. S., Hawksworth, Michael, Ingram, Heather, Johnson, Rebecca A., Kumar, Rajesh, Laity, Daniel A., Lewis, Russell D., Mathew, Jinu S., McGivern, Laura, Moses, Ian B., Palaia, Andrew T., Patel, Miheal J., Rellegue, James, Rose, Emily K., Scott, Adam, Steflik, Jeremy, Twiddle, Steven J. R.
Published in Organic process research & development (19.07.2024)
Published in Organic process research & development (19.07.2024)
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Methods and intermediates for preparing 2-[(4-{6-[(4-cyano-2-fluorobenzyl)oxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(2S)-oxetan-2-ylmethyl]-1H-benzimidazole-6-carboxylic acid, 1,3-dihydroxy-2-(hydroxymethyl)propan-2-amine salt
GYMER, ADAM EDWARD SANJI, BADLAND, MATTHEW, MATHEW, JINU SUJU, MCGIVERN, LAURA CAROLINE, DION, AMELIE, LAITY, DANIEL ANDREW, WHITE, CHLOE JOY, MOSES, IAN BRIAN, WEST, ADAM SEBASTIAN, RELLEGUE, JAMES, REYNOLDS-SCOTT, ADAM JOHN, FUSSELL, STEVEN JAMES, ROSE, EMILY KAY, CARSON, LAURA JANE ELIZABETH, CLARKE, JAMES, SVOBODA, VACLAV, MILLS, JAMES ALAN, PIBWORTH, BENJAMIN ALAN
Year of Publication 01.04.2024
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Year of Publication 01.04.2024
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