Neuropilin-1 drives tumor-specific uptake of chlorotoxin
McGonigle, Sharon, Majumder, Utpal, Kolber-Simonds, Donna, Wu, Jiayi, Hart, Andrew, Noland, Thomas, TenDyke, Karen, Custar, Daniel, Li, Danyang, Du, Hong, Postema, Maarten H D, Lai, W George, Twine, Natalie C, Woodall-Jappe, Mary, Nomoto, Kenichi
Published in Cell communication and signaling (17.06.2019)
Published in Cell communication and signaling (17.06.2019)
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Contribution of metabolites to P450 inhibition-based drug-drug interactions: scholarship from the drug metabolism leadership group of the innovation and quality consortium metabolite group
Yu, Hongbin, Balani, Suresh K, Chen, Weichao, Cui, Donghui, He, Ling, Humphreys, W Griffith, Mao, Jialin, Lai, W George, Lee, Anthony J, Lim, Heng-Keang, MacLauchlin, Christopher, Prakash, Chandra, Surapaneni, Sekhar, Tse, Susanna, Upthagrove, Alana, Walsky, Robert L, Wen, Bo, Zeng, Zhaopie
Published in Drug metabolism and disposition (01.04.2015)
Published in Drug metabolism and disposition (01.04.2015)
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Metabolic switching of BILR 355 in the presence of ritonavir. II. Uncovering novel contributions by gut bacteria and aldehyde oxidase
Li, Yongmei, Xu, Jun, Lai, W George, Whitcher-Johnstone, Andrea, Tweedie, Donald J
Published in Drug metabolism and disposition (01.06.2012)
Published in Drug metabolism and disposition (01.06.2012)
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Synthesis and Structure of Two New Mycolactones Isolated from M. ulcerans subsp. shinshuense
Hande, Sudhir M, Kazumi, Yuko, Lai, W. George, Jackson, Katrina L, Maeda, Shinji, Kishi, Yoshito
Published in Organic letters (07.09.2012)
Published in Organic letters (07.09.2012)
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Metabolic switching of BILR 355 in the presence of ritonavir. I. Identifying an unexpected disproportionate human metabolite
Li, Yongmei, Lai, W George, Whitcher-Johnstone, Andrea, Busacca, Carl A, Eriksson, Magnus C, Lorenz, Jon C, Tweedie, Donald J
Published in Drug metabolism and disposition (01.06.2012)
Published in Drug metabolism and disposition (01.06.2012)
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Microphysiological systems for ADME-related applications: current status and recommendations for system development and characterization
Fowler, Stephen, Chen, Wen Li Kelly, Duignan, David B, Gupta, Anshul, Hariparsad, Niresh, Kenny, Jane R, Lai, W. George, Liras, Jennifer, Phillips, Jonathan A, Gan, Jinping
Published in Lab on a chip (07.02.2020)
Published in Lab on a chip (07.02.2020)
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Pharmacokinetic/pharmacodynamic drug–drug interactions of avatrombopag when coadministered with dual or selective CYP2C9 and CYP3A interacting drugs
Nomoto, Maiko, Zamora, Cynthia A., Schuck, Edgar, Boyd, Peter, Chang, Min‐Kun, Aluri, Jagadeesh, Siu, Y. Amy, Lai, W. George, Yasuda, Sanae, Ferry, Jim, Rege, Bhaskar
Published in British journal of clinical pharmacology (01.05.2018)
Published in British journal of clinical pharmacology (01.05.2018)
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Metabolic disposition of H3B-8800, an orally available small-molecule splicing modulator, in rats, monkeys, and humans
Rioux, Nathalie, Smith, Sherri, Colombo, Federico, Kim, Amy, Lai, W. George, Nix, Darrell, Siu, Y. Amy, Schindler, Joanne, Smith, Peter G.
Published in Xenobiotica (01.09.2020)
Published in Xenobiotica (01.09.2020)
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Reversible inhibition of human carboxylesterases by acyl glucuronides
Inoue, Natalie R, Hall, Adrian, Lai, W George, Williams, Eric T
Published in Drug metabolism and disposition (01.04.2013)
Published in Drug metabolism and disposition (01.04.2013)
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Stereoselective metabolism of pyrido[3,2-D]pyrimidine-containing compounds by aldehyde oxidase
He, Xiaowei, Amy Siu, Y., David Hong, W., Benayoud, Farid, George Lai, W.
Published in Drug metabolism and pharmacokinetics (01.01.2018)
Published in Drug metabolism and pharmacokinetics (01.01.2018)
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Journal Article
Probing the specificity of the S1 binding site of M222 mutants of subtilisin B. lentus with boronic acid inhibitors
Stabile, Michele R., George Lai, W., DeSantis, Grace, Gold, Marvin, Bryan Jones, J., Mitchinson, Colin, Bott, Richard R., Graycar, Thomas P., Liu, Chung-Cheng
Published in Bioorganic & medicinal chemistry letters (05.11.1996)
Published in Bioorganic & medicinal chemistry letters (05.11.1996)
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