Hypoxia induces myeloid‐derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C‐C motif) ligand 26
Chiu, David Kung‐Chun, Xu, Iris Ming‐Jing, Lai, Robin Kit‐Ho, Tse, Aki Pui‐Wah, Wei, Larry Lai, Koh, Hui‐Yu, Li, Lynna Lan, Lee, Derek, Lo, Regina Cheuk‐Lam, Wong, Chun‐Ming, Ng, Irene Oi‐Lin, Wong, Carmen Chak‐Lui
Published in Hepatology (Baltimore, Md.) (01.09.2016)
Published in Hepatology (Baltimore, Md.) (01.09.2016)
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Journal Article
Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma
Chiu, David Kung-Chun, Tse, Aki Pui-Wah, Xu, Iris Ming-Jing, Di Cui, Jane, Lai, Robin Kit-Ho, Li, Lynna Lan, Koh, Hui-Yu, Tsang, Felice Ho-Ching, Wei, Larry Lai, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Nature communications (11.09.2017)
Published in Nature communications (11.09.2017)
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Journal Article
Lysyl oxidase‐like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma
Wong, Carmen Chak‐Lui, Tse, Aki Pui‐Wah, Huang, Yan‐Ping, Zhu, Yan‐Ting, Chiu, David Kung‐Chun, Lai, Robin Kit‐Ho, Au, Sandy Leung‐Kuen, Kai, Alan Ka‐Lun, Lee, Joyce Man‐Fong, Wei, Larry Lai, Tsang, Felice Ho‐Ching, Lo, Regina Cheuk‐Lam, Shi, Jue, Zheng, Yong‐Ping, Wong, Chun‐Ming, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.11.2014)
Published in Hepatology (Baltimore, Md.) (01.11.2014)
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Journal Article
HELLS Regulates Chromatin Remodeling and Epigenetic Silencing of Multiple Tumor Suppressor Genes in Human Hepatocellular Carcinoma
Law, Cheuk‐Ting, Wei, Lai, Tsang, Felice Ho‐Ching, Chan, Cerise Yuen‐Ki, Xu, Iris Ming‐Jing, Lai, Robin Kit‐Ho, Ho, Daniel Wai‐Hung, Lee, Joyce Man‐Fong, Wong, Carmen Chak‐Lui, Ng, Irene Oi‐Lin, Wong, Chun‐Ming
Published in Hepatology (Baltimore, Md.) (01.05.2019)
Published in Hepatology (Baltimore, Md.) (01.05.2019)
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Journal Article
Transketolase counteracts oxidative stress to drive cancer development
Xu, Iris Ming-Jing, Lai, Robin Kit-Ho, Lin, Shu-Hai, Tse, Aki Pui-Wah, Chiu, David Kung-Chun, Koh, Hui-Yu, Law, Cheuk-Ting, Wong, Chun-Ming, Cai, Zongwei, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2016)
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Journal Article
Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma
Lee, Derek, Xu, Iris Ming‐Jing, Chiu, David Kung‐Chun, Leibold, Josef, Tse, Aki Pui‐Wah, Bao, Macus Hao‐Ran, Yuen, Vincent Wai‐Hin, Chan, Cerise Yuen‐Ki, Lai, Robin Kit‐Ho, Chin, Don Wai‐Ching, Chan, Daniel For‐Fan, Cheung, Tan‐To, Chok, Siu‐Ho, Wong, Chun‐Ming, Lowe, Scott W., Ng, Irene Oi‐Lin, Wong, Carmen Chak‐Lui
Published in Hepatology (Baltimore, Md.) (01.04.2019)
Published in Hepatology (Baltimore, Md.) (01.04.2019)
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Journal Article
Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway
Kung-Chun Chiu, David, Pui-Wah Tse, Aki, Law, Cheuk-Ting, Ming-Jing Xu, Iris, Lee, Derek, Chen, Mengnuo, Kit-Ho Lai, Robin, Wai-Hin Yuen, Vincent, Wing-Sum Cheu, Jacinth, Wai-Hung Ho, Daniel, Wong, Chun-Ming, Zhang, Huafeng, Ng, Irene Oi-Lin, Chak-Lui Wong, Carmen
Published in Cell death & disease (09.12.2019)
Published in Cell death & disease (09.12.2019)
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Journal Article
Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multilayered Protection Against Reactive Oxygen Species
Lee, Derek, Zhang, Misty Shuo, Tsang, Felice Ho‐Ching, Bao, Macus Hao‐Ran, Xu, Iris Ming‐Jing, Lai, Robin Kit‐Ho, Chiu, David Kung‐Chun, Tse, Aki Pui‐Wah, Law, Cheuk‐Ting, Chan, Cerise Yuen‐Ki, Yuen, Vincent Wai‐Hin, Chui, Noreen Nog‐Qin, Ng, Irene Oi‐Lin, Wong, Chun‐Ming, Wong, Carmen Chak‐Lui
Published in Hepatology (Baltimore, Md.) (01.08.2021)
Published in Hepatology (Baltimore, Md.) (01.08.2021)
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Journal Article
Switching of pyruvate kinase isoform L to M2 promotes metabolic reprogramming in hepatocarcinogenesis
Wong, Carmen Chak-Lui, Au, Sandy Leung-Kuen, Tse, Aki Pui-Wah, Xu, Iris Ming-Jing, Lai, Robin Kit-Ho, Chiu, David Kung-Chun, Wei, Larry Lai, Fan, Dorothy Ngo-Yin, Tsang, Felice Ho-Ching, Lo, Regina Cheuk-Lam, Wong, Chun-Ming, Ng, Irene Oi-Lin
Published in PloS one (26.12.2014)
Published in PloS one (26.12.2014)
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Journal Article
Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma
Lee, Derek, Xu, Iris Ming-Jing, Chiu, David Kung-Chun, Lai, Robin Kit-Ho, Tse, Aki Pui-Wah, Lan Li, Lynna, Law, Cheuk-Ting, Tsang, Felice Ho-Ching, Wei, Larry Lai, Chan, Cerise Yuen-Ki, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in The Journal of clinical investigation (01.05.2017)
Published in The Journal of clinical investigation (01.05.2017)
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Journal Article
NDUFA4L2 Fine-tunes Oxidative Stress in Hepatocellular Carcinoma
Lai, Robin Kit-Ho, Xu, Iris Ming-Jing, Chiu, David Kung-Chun, Tse, Aki Pui-Wah, Wei, Larry Lai, Law, Cheuk-Ting, Lee, Derek, Wong, Chun-Ming, Wong, Maria Pik, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Clinical cancer research (15.06.2016)
Published in Clinical cancer research (15.06.2016)
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Journal Article
Specific bile acids inhibit hepatic fatty acid uptake in mice
Nie, Biao, Park, Hyo Min, Kazantzis, Melissa, Lin, Min, Henkin, Amy, Ng, Stephanie, Song, Sujin, Chen, Yuli, Tran, Heather, Lai, Robin, Her, Chris, Maher, Jacquelyn J., Forman, Barry M., Stahl, Andreas
Published in Hepatology (Baltimore, Md.) (01.10.2012)
Published in Hepatology (Baltimore, Md.) (01.10.2012)
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Journal Article
Abstract 882: Thioredoxin system inhibition using auranofin represents a new therapeutic approach for hepatocellular carcinoma
Lee, Derek, Xu, Iris Ming-Jing, Chiu, David Kung-Chun, Lai, Robin Kit-Ho, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 2445: Oxidative stress induction through TXNRD1 inhibition as a therapeutic strategy in hepatocellular carcinoma treatment
Lee, Derek, Xu, Iris Ming Jing, Chiu, David Kung Chun, Lai, Robin Kit Ho, Wong, Chun Ming, Ng, Irene Oi Lin, Wong, Carmen Chak Lui
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 436: Folate cycle represents a new metabolic vulnerability for hepatocellular carcinoma treatment
Lee, Derek, Xu, Iris Ming-Jing, Chiu, David Kung-Chun, Lai, Robin Kit-Ho, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 2429: HIF-1α repressed glycerol-3-phosphate shuttle to reduce oxidative stress in liver cancer
ZHANG, Shuo, LAI, Robin Kit-Ho, CHIU, David Kung-Chun, XU, Iris Mingjing, TSE, Aki Pui Wah, WONG, Chun-Ming, NG, Irene Oi Lin, WONG, Carmen Chak Lui
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 2415: HEY1 counteracts hypoxia-induced oxidative stress via transcriptionally repressing PINK1 in hepatocellular carcinoma
Chiu, David Kung-Chun, Xu, Iris Ming-Jing, Lai, Robin Kit-Ho, Tse, Aki Pui-Wah, Law, Dicky Cheuk-Ting, Yuen, Vincent Wai-Hin, Wei, Larry Lai, Koh, Hui-Yu, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Induction of Oxidative Stress via Inhibition of Thioredoxin Reductase 1 is an Effective Therapeutic Approach for Hepatocellular Carcinoma
Lee, Derek, Xu, Iris Ming-Jing, Chiu, David Kung-Chun, Leibold, Josef, Tse, Aki Pui-Wah, Bao, Macus Hao-Ran, Yuen, Vincent Wai-Hin, Chan, Cerise Yuen-Ki, Lai, Robin Kit-Ho, Chin, Don Wai-Ching, Chan, Daniel For-Fan, Cheung, Tan-To, Chok, Siu-Ho, Wong, Chun-Ming, Lowe, Scott W., Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Hepatology (Baltimore, Md.) (21.03.2019)
Published in Hepatology (Baltimore, Md.) (21.03.2019)
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Journal Article
Abstract 2941: Inhibition of hypoxia-induced ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2) restrains myeloid-derived suppressor cell (MDSC) accumulation and sensitizes tumors to immune checkpoint inhibition
Chiu, David Kung-Chun, Tse, Aki Pui-Wah, Xu, Iris Ming-Jing, Lai, Robin Kit-Ho, Koh, Hui-yu, Tsang, Felice Ho-Ching, Wei, Larry Lai, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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