AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia
Poh, Luting, Fann, David Y., Wong, Peiyan, Lim, Hong Meng, Foo, Sok Lin, Kang, Sung-Wook, Rajeev, Vismitha, Selvaraji, Sharmelee, Iyer, Vinaya Rajagopal, Parathy, Nageiswari, Khan, Mohammad Badruzzaman, Hess, David C., Jo, Dong-Gyu, Drummond, Grant R., Sobey, Christopher G., Lai, Mitchell K. P., Chen, Christopher Li-Hsian, Lim, Lina H. K., Arumugam, Thiruma V.
Published in Molecular psychiatry (01.08.2021)
Published in Molecular psychiatry (01.08.2021)
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The role of inflammasomes in vascular cognitive impairment
Poh, Luting, Sim, Wei Liang, Jo, Dong-Gyu, Dinh, Quynh Nhu, Drummond, Grant R, Sobey, Christopher G, Chen, Christopher Li-Hsian, Lai, Mitchell K P, Fann, David Y, Arumugam, Thiruma V
Published in Molecular neurodegeneration (09.01.2022)
Published in Molecular neurodegeneration (09.01.2022)
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Plasma osteopontin as a biomarker of Alzheimer’s disease and vascular cognitive impairment
Chai, Yuek Ling, Chong, Joyce R., Raquib, Ainiah R., Xu, Xin, Hilal, Saima, Venketasubramanian, Narayanaswamy, Tan, Boon Yeow, Kumar, Alan P., Sethi, Gautam, Chen, Christopher P., Lai, Mitchell K. P.
Published in Scientific reports (17.02.2021)
Published in Scientific reports (17.02.2021)
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Chronic cerebral hypoperfusion: a critical feature in unravelling the etiology of vascular cognitive impairment
Rajeev, Vismitha, Chai, Yuek Ling, Poh, Luting, Selvaraji, Sharmelee, Fann, David Y, Jo, Dong-Gyu, De Silva, T Michael, Drummond, Grant R, Sobey, Christopher G, Arumugam, Thiruma V, Chen, Christopher P, Lai, Mitchell K P
Published in Acta neuropathologica communications (12.06.2023)
Published in Acta neuropathologica communications (12.06.2023)
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Inflammatory panel cytokines are elevated in the neocortex of late-stage Alzheimer's disease but not Lewy body dementias
Chai, Yuek Ling, Lee, Jasinda H, Chong, Joyce R, Ballard, Clive, Francis, Paul T, Kennedy, Brian K, Arumugam, Thiruma V, Chen, Christopher P, Aarsland, Dag, Lai, Mitchell K P
Published in Journal of neuroinflammation (08.05.2023)
Published in Journal of neuroinflammation (08.05.2023)
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Interactive effect of diabetes mellitus and subclinical MRI markers of cerebrovascular disease on cognitive decline and incident dementia: a memory-clinic study
Cui, Jiangbo, Robert, Caroline, Teh, Chia May, Jun Yi, Eddie Chong, Chong, Joyce R, Tan, Boon Yeow, Venketasubramanian, Narayanaswamy, Lai, Mitchell K P, Chen, Christopher, Hilal, Saima
Published in Alzheimer's research & therapy (03.10.2024)
Published in Alzheimer's research & therapy (03.10.2024)
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Lipidomics profiling reveals distinct patterns of plasma sphingolipid alterations in Alzheimer's disease and vascular dementia
Chua, Xin Ying, Torta, Federico, Chong, Joyce R, Venketasubramanian, Narayanaswamy, Hilal, Saima, Wenk, Markus R, Chen, Christopher P, Arumugam, Thiruma V, Herr, Deron R, Lai, Mitchell K P
Published in Alzheimer's research & therapy (12.12.2023)
Published in Alzheimer's research & therapy (12.12.2023)
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Immunomodulatory sphingosine-1-phosphates as plasma biomarkers of Alzheimer's disease and vascular cognitive impairment
Chua, Xin Ying, Chai, Yuek Ling, Chew, Wee Siong, Chong, Joyce R, Ang, Hui Li, Xiang, Ping, Camara, Kaddy, Howell, Amy R, Torta, Federico, Wenk, Markus R, Hilal, Saima, Venketasubramanian, Narayanaswamy, Chen, Christopher P, Herr, Deron R, Lai, Mitchell K P
Published in Alzheimer's research & therapy (30.09.2020)
Published in Alzheimer's research & therapy (30.09.2020)
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Altered relaxin family receptors RXFP1 and RXFP3 in the neocortex of depressed Alzheimer’s disease patients
Lee, Jasinda H., Koh, Shu Qing, Guadagna, Simone, Francis, Paul T., Esiri, Margaret M., Chen, Christopher P., Wong, Peter T.-H., Dawe, Gavin S., Lai, Mitchell K. P.
Published in Psychopharmacology (01.02.2016)
Published in Psychopharmacology (01.02.2016)
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Elevated Soluble TNF-Receptor 1 in the Serum of Predementia Subjects with Cerebral Small Vessel Disease
Salai, Kaung H T, Wu, Liu-Yun, Chong, Joyce R, Chai, Yuek Ling, Gyanwali, Bibek, Robert, Caroline, Hilal, Saima, Venketasubramanian, Narayanaswamy, Dawe, Gavin S, Chen, Christopher P, Lai, Mitchell K P
Published in Biomolecules (Basel, Switzerland) (01.03.2023)
Published in Biomolecules (Basel, Switzerland) (01.03.2023)
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Serum Brevican as a Biomarker of Cerebrovascular Disease in an Elderly Cognitively Impaired Cohort
Chia, Rachel S L, Minta, Karolina, Wu, Liu-Yun, Salai, Kaung H T, Chai, Yuek Ling, Hilal, Saima, Venketasubramanian, Narayanaswamy, Chen, Christopher P, Chong, Joyce R, Lai, Mitchell K P
Published in Biomolecules (Basel, Switzerland) (01.01.2024)
Published in Biomolecules (Basel, Switzerland) (01.01.2024)
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An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias
Datta, Arnab, Chai, Yuek Ling, Tan, Jing Min, Lee, Jasinda H, Francis, Paul T, Chen, Christopher P, Sze, Siu Kwan, Lai, Mitchell K P
Published in Molecular brain (11.08.2017)
Published in Molecular brain (11.08.2017)
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Biological Effects of Naturally Occurring Sphingolipids, Uncommon Variants, and Their Analogs
Lai, Mitchell K. P., Chew, Wee Siong, Torta, Federico, Rao, Angad, Harris, Greg L., Chun, Jerold, Herr, Deron R.
Published in Neuromolecular Medicine (01.09.2016)
Published in Neuromolecular Medicine (01.09.2016)
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Book Review
O-GlcNAcylation as a Therapeutic Target for Alzheimer’s Disease
Park, Jinsu, Lai, Mitchell K. P., Arumugam, Thiruma V., Jo, Dong-Gyu
Published in Neuromolecular medicine (01.06.2020)
Published in Neuromolecular medicine (01.06.2020)
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Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR)
Gallart-Palau, Xavier, Serra, Aida, Wong, Andrew See Weng, Sandin, Sara, Lai, Mitchell K. P., Chen, Christopher P., Kon, Oi Lian, Sze, Siu Kwan
Published in Scientific reports (30.09.2015)
Published in Scientific reports (30.09.2015)
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Blood-based high sensitivity measurements of beta-amyloid and phosphorylated tau as biomarkers of Alzheimer’s disease: a focused review on recent advances
Chong, Joyce R., Ashton, Nicholas J., Karikari, Thomas K., Tanaka, Tomotaka, Schöll, Michael, Zetterberg, Henrik, Blennow, Kaj, Chen, Christopher P., Lai, Mitchell K.P.
Published in Journal of neurology, neurosurgery and psychiatry (01.11.2021)
Published in Journal of neurology, neurosurgery and psychiatry (01.11.2021)
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Isoform‐specific upregulation of FynT kinase expression is associated with tauopathy and glial activation in Alzheimer's disease and Lewy body dementias
Low, Clara Y. B., Lee, Jasinda H., Lim, Frances T. W., Lee, Chingli, Ballard, Clive, Francis, Paul T., Lai, Mitchell K. P., Tan, Michelle G. K.
Published in Brain pathology (Zurich, Switzerland) (01.03.2021)
Published in Brain pathology (Zurich, Switzerland) (01.03.2021)
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