Nuclear receptor/Wnt beta-catenin interactions are regulated via differential CBP/p300 coactivator usage
Ono, Masaya, Lai, Keane K Y, Wu, Kaijin, Nguyen, Cu, Lin, David P, Murali, Ramachandran, Kahn, Michael
Published in PloS one (18.07.2018)
Published in PloS one (18.07.2018)
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Extracellular matrix dynamics in hepatocarcinogenesis: a comparative proteomics study of PDGFC transgenic and Pten null mouse models
Lai, Keane K Y, Shang, Sufen, Lohia, Neha, Booth, Garrett C, Masse, Derek J, Fausto, Nelson, Campbell, Jean S, Beretta, Laura
Published in PLoS genetics (01.06.2011)
Published in PLoS genetics (01.06.2011)
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Targeted genomic profiling identifies frequent deleterious mutations in FAT4 and TP53 genes in HBV-associated hepatocellular carcinoma
Huang, Fung-Yu, Wong, Danny Ka-Ho, Tsui, Vivien Wai-Man, Seto, Wai-Kay, Mak, Lung-Yi, Cheung, Tan-To, Lai, Keane K-Y, Yuen, Man-Fung
Published in BMC cancer (08.08.2019)
Published in BMC cancer (08.08.2019)
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Comprehensive and quantitative proteome profiling of the mouse liver and plasma
Lai, Keane K. Y., Kolippakkam, Deepak, Beretta, Laura
Published in Hepatology (Baltimore, Md.) (01.03.2008)
Published in Hepatology (Baltimore, Md.) (01.03.2008)
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Improved Reflexive Testing Algorithm for Hepatitis C Infection Using Signal-to-Cutoff Ratios of a Hepatitis C Virus Antibody Assay
LAI, Keane K. Y, MING JIN, SHAN YUAN, LARSON, Meaghan F, DOMINITZ, Jason A, BANKSON, Daniel D
Published in Clinical chemistry (Baltimore, Md.) (01.07.2011)
Published in Clinical chemistry (Baltimore, Md.) (01.07.2011)
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Synergistic steatohepatitis by moderate obesity and alcohol in mice despite increased adiponectin and p-AMPK
Xu, Jun, Lai, Keane K.Y, Verlinsky, Alla, Lugea, Aurelia, French, Samuel W, Cooper, Marcus P, Ji, Cheng, Tsukamoto, Hidekazu
Published in Journal of hepatology (01.09.2011)
Published in Journal of hepatology (01.09.2011)
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Magnetic resonance imaging for characterization of hepatocellular carcinoma metabolism
Wang, Lixia, Yang, Ju Dong, Yoo, Charles C, Lai, Keane K Y, Braun, Jonathan, McGovern, Dermot P B, Xie, Yibin, Pandol, Stephen J, Lu, Shelly C, Li, Debiao
Published in Frontiers in physiology (15.12.2022)
Published in Frontiers in physiology (15.12.2022)
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Midnolin Regulates Liver Cancer Cell Growth In Vitro and In Vivo
Kweon, Soo-Mi, Kim, Gayeoun, Jeong, Yunseong, Huang, Wendong, Lee, Ju-Seog, Lai, Keane K Y
Published in Cancers (10.03.2022)
Published in Cancers (10.03.2022)
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p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair
Lai, Keane K Y, Hu, Xiaohui, Chosa, Keisuke, Nguyen, Cu, Lin, David P, Lai, Keith K, Kato, Nobuo, Higuchi, Yusuke, Highlander, Sarah K, Melendez, Elizabeth, Eriguchi, Yoshihiro, Fueger, Patrick T, Ouellette, Andre J, Chimge, Nyam-Osor, Ono, Masaya, Kahn, Michael
Published in Cancers (14.03.2021)
Published in Cancers (14.03.2021)
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Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein–Receptor–Related Proteins 5 and 6
Lai, Keane K.Y, Kweon, Soo-Mi, Chi, Feng, Hwang, Edward, Kabe, Yasuaki, Higashiyama, Reiichi, Qin, Lan, Yan, Rui, Wu, Raymond P, Fujii, Naoaki, French, Samuel, Xu, Jun, Wang, Jian-Ying, Murali, Ramanchadran, Mishra, Lopa, Lee, Ju-Seog, Ntambi, James M, Tsukamoto, Hidekazu
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2017)
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Heterozygous midnolin knockout attenuates severity of nonalcoholic fatty liver disease in mice fed a Western-style diet high in fat, cholesterol, and fructose
Kweon, Soo-Mi, Irimia-Dominguez, Jose, Kim, Gayeoun, Fueger, Patrick T, Asahina, Kinji, Lai, Keith K, Allende, Daniela S, Lai, Quincy R, Lou, Chih-Hong, Tsark, Walter M, Yang, Ju Dong, Ng, Dominic S, Lee, Ju-Seog, Tso, Patrick, Huang, Wendong, Lai, Keane K Y
Published in American journal of physiology: Gastrointestinal and liver physiology (01.08.2023)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.08.2023)
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HBV X protein mutations affect HBV transcription and association of histone-modifying enzymes with covalently closed circular DNA
Chong, Chun Kong, Cheng, Ching Yan Serene, Tsoi, Sin Yi Jasmine, Huang, Fung-Yu, Liu, Fen, Fung, James, Seto, Wai-Kay, Lai, Keane K.-Y., Lai, Ching-Lung, Yuen, Man-Fung, Wong, Danny Ka-Ho
Published in Scientific reports (21.01.2020)
Published in Scientific reports (21.01.2020)
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Animal Models: Challenges and Opportunities to Determine Optimal Experimental Models of Pancreatitis and Pancreatic Cancer
Saloman, Jami L, Albers, Kathryn M, Cruz-Monserrate, Zobeida, Davis, Brian M, Edderkaoui, Mouad, Eibl, Guido, Epouhe, Ariel Y, Gedeon, Jeremy Y, Gorelick, Fred S, Grippo, Paul J, Groblewski, Guy E, Husain, Sohail Z, Lai, Keane K Y, Pandol, Stephen J, Uc, Aliye, Wen, Li, Whitcomb, David C
Published in Pancreas (01.07.2019)
Published in Pancreas (01.07.2019)
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Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer
Manegold, Philipp, Lai, Keane K Y, Wu, Yongfeng, Teo, Jia-Ling, Lenz, Heinz-Josef, Genyk, Yuri S, Pandol, Stephen J, Wu, Kaijin, Lin, David P, Chen, Yibu, Nguyen, Cu, Zhao, Yi, Kahn, Michael
Published in Cancers (29.03.2018)
Published in Cancers (29.03.2018)
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Differential Kat3 Usage Orchestrates the Integration of Cellular Metabolism with Differentiation
Hu, Xiaohui, Ono, Masaya, Chimge, Nyam-Osor, Chosa, Keisuke, Nguyen, Cu, Melendez, Elizabeth, Lou, Chih-Hong, Lim, Punnajit, Termini, John, Lai, Keane K. Y., Fueger, Patrick T., Teo, Jia-Ling, Higuchi, Yusuke, Kahn, Michael
Published in Cancers (23.11.2021)
Published in Cancers (23.11.2021)
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Journal Article
Targeting the CBP/β-Catenin Interaction to Suppress Activation of Cancer-Promoting Pancreatic Stellate Cells
Che, Mingtian, Kweon, Soo-Mi, Teo, Jia-Ling, Yuan, Yate-Ching, Melstrom, Laleh G, Waldron, Richard T, Lugea, Aurelia, Urrutia, Raul A, Pandol, Stephen J, Lai, Keane K Y
Published in Cancers (05.06.2020)
Published in Cancers (05.06.2020)
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Thioacetamide-Induced Norepinephrine Production by Hepatocytes is Associated with Hepatic Stellate Cell Activation and Liver Fibrosis
Tang, Wei-Chien, Chang, Ya-Wen, Che, Mingtian, Wang, Mei-Hui, Lai, Keith K, Fueger, Patrick T, Huang, Wendong, Lin, Shwu-Bin, Lai, Keane K Y
Published in Current molecular pharmacology (01.01.2022)
Published in Current molecular pharmacology (01.01.2022)
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Journal Article
The Mode of Stem Cell Division Is Dependent on the Differential Interaction of β-Catenin with the Kat3 Coactivators CBP or p300
Lukaszewicz, Agnes I, Nguyen, Cu, Melendez, Elizabeth, Lin, David P, Teo, Jia-Ling, Lai, Keane K Y, Huttner, Wieland B, Shi, Song-Hai, Kahn, Michael
Published in Cancers (09.07.2019)
Published in Cancers (09.07.2019)
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