HCV genotyping from NGS short reads and its application in genotype detection from HCV mixed infected plasma
Qiu, Ping, Stevens, Richard, Wei, Bo, Lahser, Fred, Howe, Anita Y M, Klappenbach, Joel A, Marton, Matthew J
Published in PloS one (01.04.2015)
Published in PloS one (01.04.2015)
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Structure–Activity Relationship (SAR) Optimization of 6‑(Indol-2-yl)pyridine-3-sulfonamides: Identification of Potent, Selective, and Orally Bioavailable Small Molecules Targeting Hepatitis C (HCV) NS4B
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Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Discovery of novel HCV inhibitors: Synthesis and biological activity of 6-(indol-2-yl)pyridine-3-sulfonamides targeting hepatitis C virus NS4B
Zhang, Xiaoyan, Zhang, Nanjing, Chen, Guangming, Turpoff, Anthony, Ren, Hongyu, Takasugi, James, Morrill, Christie, Zhu, Jin, Li, Chunshi, Lennox, William, Paget, Steven, Liu, Yalei, Almstead, Neil, George Njoroge, F., Gu, Zhengxian, Komatsu, Takashi, Clausen, Valerie, Espiritu, Christine, Graci, Jason, Colacino, Joseph, Lahser, Fred, Risher, Nicole, Weetall, Marla, Nomeir, Amin, Karp, Gary M.
Published in Bioorganic & medicinal chemistry letters (01.07.2013)
Published in Bioorganic & medicinal chemistry letters (01.07.2013)
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Interplay of Amino Acid Residues at Positions 28 and 31 in NS5A Defines Resistance Pathways in Hepatitis C Virus Genotype 2
Asante-Appiah, Ernest, Ingravallo, Paul, McMonagle, Patricia, Bystol, Karin, Xia, Ellen, Curry, Stephanie, Qiu, Ping, Black, Stuart, Chase, Robert, Liu, Rong, Lahser, Fred
Published in Antimicrobial agents and chemotherapy (01.12.2019)
Published in Antimicrobial agents and chemotherapy (01.12.2019)
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Development and Validation of a Template-Independent Next-Generation Sequencing Assay for Detecting Low-Level Resistance-Associated Variants of Hepatitis C Virus
Wei, Bo, Kang, John, Kibukawa, Miho, Chen, Lei, Qiu, Ping, Lahser, Fred, Marton, Matthew, Levitan, Diane
Published in The Journal of molecular diagnostics : JMD (01.09.2016)
Published in The Journal of molecular diagnostics : JMD (01.09.2016)
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Antiviral activity of boceprevir monotherapy in treatment-naive subjects with chronic hepatitis C genotype 2/3
Silva, Marcelo O, Treitel, Michelle, Graham, Donald J, Curry, Stephanie, Frontera, Maria J, McMonagle, Patricia, Gupta, Samir, Hughes, Eric, Chase, Robert, Lahser, Fred, Barnard, Richard J.O, Howe, Anita Y.M, Howe, John A
Published in Journal of hepatology (01.07.2013)
Published in Journal of hepatology (01.07.2013)
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Efficacy and safety of a two‐drug direct‐acting antiviral agent regimen ruzasvir 180 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4, 5 or 6
Lawitz, Eric, Gane, Edward, Feld, Jordan J., Buti, Maria, Foster, Graham R., Rabinovitz, Mordechai, Burnevich, Eduard, Katchman, Helena, Tomasiewicz, Krzysztof, Lahser, Fred, Jackson, Beth, Shaughnessy, Melissa, Klopfer, Stephanie, Yeh, Wendy W., Robertson, Michael N., Hanna, George J., Barr, Eliav, Platt, Heather L., Gordon, Stuart C., Lawitz, Eric J., Ruane, Peter Jerome, Sahota, Amandeep, Terrault, Norah A., Tsai, Naoky, Kalathil, Sumodh C., Reddy, Gautham, Ghesquiere, Wayne, Borgia, Sergio, Conway, Brian, Feld, Jordan, Tsoi, Keith, Cooper, Curtis L., Ghali, Peter Maged, Thompson, Alexander James Venn, Panero, Jose Luis Calleja, Ferret, Sabela Lens Maria Buti, Franinan, Luis Margusino, Angeles Castro Iglesias, Maria, Brown, Ashley, Agarwal, Kaushik, Foster, Graham, Cramp, Matthew, Zuckerman, Eli, Veitsman, Ella, Cohen, Michal, Lurie, Yoav, Ari, Ziv Ben, Janczewska, Ewa, Szymczak, Aleksandra, Halota, Waldemar, Flisiak, Robert, Mahomed, Adam, Sonderup, Mark Wayne, Punt, Zelda Erika, Kgomo, Mpho Klaas, Bernhardi, David C, Burnevich, Eduard Z., Kizhlo, Svetlana
Published in Journal of viral hepatitis (01.09.2019)
Published in Journal of viral hepatitis (01.09.2019)
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Discovery of 2-(4-sulfonamidophenyl)-indole 3-carboxamides as potent and selective inhibitors with broad hepatitis C virus genotype activity targeting HCV NS4B
Zhang, Nanjing, Turpoff, Anthony, Zhang, Xiaoyan, Huang, Song, Liu, Yalei, Almstead, Neil, Njoroge, F. George, Gu, Zhengxian, Graci, Jason, Jung, Stephen P., Pichardo, John, Colacino, Joseph, Lahser, Fred, Ingravallo, Paul, Weetall, Marla, Nomeir, Amin, Karp, Gary M.
Published in Bioorganic & medicinal chemistry letters (15.01.2016)
Published in Bioorganic & medicinal chemistry letters (15.01.2016)
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6-(Azaindol-2-yl)pyridine-3-sulfonamides as potent and selective inhibitors targeting hepatitis C virus NS4B
Chen, Guangming, Ren, Hongyu, Zhang, Nanjing, Lennox, William, Turpoff, Anthony, Paget, Steven, Li, Chunshi, Almstead, Neil, Njoroge, F. George, Gu, Zhengxian, Graci, Jason, Jung, Stephen P., Colacino, Joseph, Lahser, Fred, Zhao, Xin, Weetall, Marla, Nomeir, Amin, Karp, Gary M.
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
Published in Bioorganic & medicinal chemistry letters (15.02.2015)
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Alkyl substituted aminal derivatives of HCV NS5A inhibitor MK-8742
Yu, Wensheng, Coburn, Craig A., Nair, Anilkumar G., Wong, Michael, Tong, Ling, Dwyer, Michael P., Hu, Bin, Zhong, Bin, Hao, Jinglai, Yang, De-Yi, Selyutin, Oleg, Jiang, Yueheng, Rosenblum, Stuart B., Kim, Seong Heon, Lavey, Brian J., Zhou, Guowei, Rizvi, Razia, Shankar, Bandarpalle B., Zeng, Qingbei, Chen, Lei, Agrawal, Sony, Carr, Donna, Rokosz, Laura, Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Ingravallo, Paul, Lahser, Fred, Asante-Appiah, Ernest, Nomeir, Amin, Kozlowski, Joseph A.
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
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Discovery of potent macrocyclic HCV NS5A inhibitors
Yu, Wensheng, Vibulbhan, Bancha, Rosenblum, Stuart B., Martin, Gregory S., Vellekoop, A. Samuel, Holst, Christian L., Coburn, Craig A., Wong, Michael, Selyutin, Oleg, Ji, Tao, Zhong, Bin, Hu, Bin, Chen, Lei, Dwyer, Michael P., Jiang, Yueheng, Nair, Anilkumar G., Tong, Ling, Zeng, Qingbei, Agrawal, Sony, Carr, Donna, Rokosz, Laura, Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Ingravallo, Paul, Lahser, Fred, Asante-Appiah, Ernest, Fells, James, Kozlowski, Joseph A.
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
Published in Bioorganic & medicinal chemistry letters (01.08.2016)
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Interplay of Amino Acid Residues at Positions 28 and 31 in NS5A Defines Resistance Pathways in HCV GT2
Asante-Appiah, Ernest, Ingravallo, Paul, McMonagle, Patricia, Bystol, Karin, Xia, Ellen, Curry, Stephanie, Qiu, Ping, Black, Stuart, Chase, Robert, Liu, Rong, Lahser, Fred
Published in Antimicrobial agents and chemotherapy (09.09.2019)
Published in Antimicrobial agents and chemotherapy (09.09.2019)
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