Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease
Rangaraju, Srikant, Dammer, Eric B, Raza, Syed Ali, Rathakrishnan, Priyadharshini, Xiao, Hailian, Gao, Tianwen, Duong, Duc M, Pennington, Michael W, Lah, James J, Seyfried, Nicholas T, Levey, Allan I
Published in Molecular neurodegeneration (21.05.2018)
Published in Molecular neurodegeneration (21.05.2018)
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Journal Article
Robust quantitative susceptibility mapping via approximate message passing with parameter estimation
Huang, Shuai, Lah, James J., Allen, Jason W., Qiu, Deqiang
Published in Magnetic resonance in medicine (01.10.2023)
Published in Magnetic resonance in medicine (01.10.2023)
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Journal Article
Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level
Johnson, Erik C B, Carter, E Kathleen, Dammer, Eric B, Duong, Duc M, Gerasimov, Ekaterina S, Liu, Yue, Liu, Jiaqi, Betarbet, Ranjita, Ping, Lingyan, Yin, Luming, Serrano, Geidy E, Beach, Thomas G, Peng, Junmin, De Jager, Philip L, Haroutunian, Vahram, Zhang, Bin, Gaiteri, Chris, Bennett, David A, Gearing, Marla, Wingo, Thomas S, Wingo, Aliza P, Lah, James J, Levey, Allan I, Seyfried, Nicholas T
Published in Nature neuroscience (01.02.2022)
Published in Nature neuroscience (01.02.2022)
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Journal Article
Automated analysis of facial emotions in subjects with cognitive impairment
Jiang, Zifan, Seyedi, Salman, Haque, Rafi U, Pongos, Alvince L, Vickers, Kayci L, Manzanares, Cecelia M, Lah, James J, Levey, Allan I, Clifford, Gari D
Published in PloS one (21.01.2022)
Published in PloS one (21.01.2022)
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Journal Article
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
Jonsson, Thorlakur, Stefansson, Hreinn, Steinberg, Stacy, Jonsdottir, Ingileif, Jonsson, Palmi V, Snaedal, Jon, Bjornsson, Sigurbjorn, Huttenlocher, Johanna, Levey, Allan I, Lah, James J, Rujescu, Dan, Hampel, Harald, Giegling, Ina, Andreassen, Ole A, Engedal, Knut, Ulstein, Ingun, Djurovic, Srdjan, Ibrahim-Verbaas, Carla, Hofman, Albert, Ikram, M. Arfan, van Duijn, Cornelia M, Thorsteinsdottir, Unnur, Kong, Augustine, Stefansson, Kari
Published in The New England journal of medicine (10.01.2013)
Published in The New England journal of medicine (10.01.2013)
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Journal Article
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
Johnson, Erik C B, Dammer, Eric B, Duong, Duc M, Ping, Lingyan, Zhou, Maotian, Yin, Luming, Higginbotham, Lenora A, Guajardo, Andrew, White, Bartholomew, Troncoso, Juan C, Thambisetty, Madhav, Montine, Thomas J, Lee, Edward B, Trojanowski, John Q, Beach, Thomas G, Reiman, Eric M, Haroutunian, Vahram, Wang, Minghui, Schadt, Eric, Zhang, Bin, Dickson, Dennis W, Ertekin-Taner, Nilüfer, Golde, Todd E, Petyuk, Vladislav A, De Jager, Philip L, Bennett, David A, Wingo, Thomas S, Rangaraju, Srikant, Hajjar, Ihab, Shulman, Joshua M, Lah, James J, Levey, Allan I, Seyfried, Nicholas T
Published in Nature medicine (01.05.2020)
Published in Nature medicine (01.05.2020)
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Journal Article
Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease
Johnson, Erik C B, Dammer, Eric B, Duong, Duc M, Yin, Luming, Thambisetty, Madhav, Troncoso, Juan C, Lah, James J, Levey, Allan I, Seyfried, Nicholas T
Published in Molecular neurodegeneration (04.10.2018)
Published in Molecular neurodegeneration (04.10.2018)
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Journal Article
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis
Wingo, Aliza P, Liu, Yue, Gerasimov, Ekaterina S, Gockley, Jake, Logsdon, Benjamin A, Duong, Duc M, Dammer, Eric B, Robins, Chloe, Beach, Thomas G, Reiman, Eric M, Epstein, Michael P, De Jager, Philip L, Lah, James J, Bennett, David A, Seyfried, Nicholas T, Levey, Allan I, Wingo, Thomas S
Published in Nature genetics (01.02.2021)
Published in Nature genetics (01.02.2021)
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Journal Article
Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age
Wingo, Aliza P, Dammer, Eric B, Breen, Michael S, Logsdon, Benjamin A, Duong, Duc M, Troncosco, Juan C, Thambisetty, Madhav, Beach, Thomas G, Serrano, Geidy E, Reiman, Eric M, Caselli, Richard J, Lah, James J, Seyfried, Nicholas T, Levey, Allan I, Wingo, Thomas S
Published in Nature communications (08.04.2019)
Published in Nature communications (08.04.2019)
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Journal Article
Brain proteome-wide association study implicates novel proteins in depression pathogenesis
Wingo, Thomas S, Liu, Yue, Gerasimov, Ekaterina S, Gockley, Jake, Logsdon, Benjamin A, Duong, Duc M, Dammer, Eric B, Lori, Adriana, Kim, Paul J, Ressler, Kerry J, Beach, Thomas G, Reiman, Eric M, Epstein, Michael P, De Jager, Philip L, Lah, James J, Bennett, David A, Seyfried, Nicholas T, Levey, Allan I, Wingo, Aliza P
Published in Nature neuroscience (01.06.2021)
Published in Nature neuroscience (01.06.2021)
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Journal Article
Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice
Chalermpalanupap, Termpanit, Schroeder, Jason P, Rorabaugh, Jacki M, Liles, L Cameron, Lah, James J, Levey, Allan I, Weinshenker, David
Published in The Journal of neuroscience (03.01.2018)
Published in The Journal of neuroscience (03.01.2018)
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Journal Article
A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain
Umoh, Mfon E, Dammer, Eric B, Dai, Jingting, Duong, Duc M, Lah, James J, Levey, Allan I, Gearing, Marla, Glass, Jonathan D, Seyfried, Nicholas T
Published in EMBO molecular medicine (01.01.2018)
Published in EMBO molecular medicine (01.01.2018)
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Journal Article
Evidence for brain glucose dysregulation in Alzheimer's disease
An, Yang, Varma, Vijay R., Varma, Sudhir, Casanova, Ramon, Dammer, Eric, Pletnikova, Olga, Chia, Chee W., Egan, Josephine M., Ferrucci, Luigi, Troncoso, Juan, Levey, Allan I., Lah, James, Seyfried, Nicholas T., Legido-Quigley, Cristina, O'Brien, Richard, Thambisetty, Madhav
Published in Alzheimer's & dementia (01.03.2018)
Published in Alzheimer's & dementia (01.03.2018)
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Journal Article
The complex relationship of air pollution and neighborhood socioeconomic status and their association with cognitive decline
Christensen, Grace M., Li, Zhenjiang, Pearce, John, Marcus, Michele, Lah, James J., Waller, Lance A., Ebelt, Stefanie, Hüls, Anke
Published in Environment international (01.09.2022)
Published in Environment international (01.09.2022)
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Journal Article
Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease
Ping, Lingyan, Duong, Duc M, Yin, Luming, Gearing, Marla, Lah, James J, Levey, Allan I, Seyfried, Nicholas T
Published in Scientific data (13.03.2018)
Published in Scientific data (13.03.2018)
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Journal Article
Association of Early-Onset Alzheimer Disease With Elevated Low-Density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB
Wingo, Thomas S, Cutler, David J, Wingo, Aliza P, Le, Ngoc-Anh, Rabinovici, Gil D, Miller, Bruce L, Lah, James J, Levey, Allan I
Published in Archives of neurology (Chicago) (01.07.2019)
Published in Archives of neurology (Chicago) (01.07.2019)
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Journal Article
A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease
Seyfried, Nicholas T., Dammer, Eric B., Swarup, Vivek, Nandakumar, Divya, Duong, Duc M., Yin, Luming, Deng, Qiudong, Nguyen, Tram, Hales, Chadwick M., Wingo, Thomas, Glass, Jonathan, Gearing, Marla, Thambisetty, Madhav, Troncoso, Juan C., Geschwind, Daniel H., Lah, James J., Levey, Allan I.
Published in Cell systems (25.01.2017)
Published in Cell systems (25.01.2017)
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