Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET
Rankin, Erinn B., Fuh, Katherine C., Castellini, Laura, Viswanathan, Kartik, Finger, Elizabeth C., Diep, Anh N., LaGory, Edward L., Kariolis, Mihalis S., Chan, Andy, Lindgren, David, Axelson, Håkan, Miao, Yu R., Krieg, Adam J., Giaccia, Amato J.
Published in Proceedings of the National Academy of Sciences - PNAS (16.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (16.09.2014)
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Journal Article
Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma
LaGory, Edward L., Wu, Colleen, Taniguchi, Cullen M., Ding, Chien-Kuang Cornelia, Chi, Jen-Tsan, von Eyben, Rie, Scott, David A., Richardson, Adam D., Giaccia, Amato J.
Published in Cell reports (Cambridge) (07.07.2015)
Published in Cell reports (Cambridge) (07.07.2015)
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Journal Article
The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
Moon, Eui Jung, Mello, Stephano S., Li, Caiyun G., Chi, Jen-Tsan, Thakkar, Kaushik, Kirkland, Jacob G., Lagory, Edward L., Lee, Ik Jae, Diep, Anh N., Miao, Yu, Rafat, Marjan, Vilalta, Marta, Castellini, Laura, Krieg, Adam J., Graves, Edward E., Attardi, Laura D., Giaccia, Amato J.
Published in Nature communications (14.07.2021)
Published in Nature communications (14.07.2021)
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Journal Article
Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity
Chen, Xingqi, Litzenburger, Ulrike M., Wei, Yuning, Schep, Alicia N., LaGory, Edward L., Choudhry, Hani, Giaccia, Amato J., Greenleaf, William J., Chang, Howard Y.
Published in Nature communications (02.11.2018)
Published in Nature communications (02.11.2018)
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Journal Article
ACSL3 regulates lipid droplet biogenesis and ferroptosis sensitivity in clear cell renal cell carcinoma
Klasson, Timothy D, LaGory, Edward L, Zhao, Hongjuan, Huynh, Star K, Papandreou, Ioanna, Moon, Eui Jung, Giaccia, Amato J
Published in Cancer & metabolism (03.10.2022)
Published in Cancer & metabolism (03.10.2022)
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Journal Article
Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes
Taniguchi, Cullen M, Finger, Elizabeth C, Krieg, Adam J, Wu, Colleen, Diep, Anh N, LaGory, Edward L, Wei, Kevin, McGinnis, Lisa M, Yuan, Jenny, Kuo, Calvin J, Giaccia, Amato J
Published in Nature medicine (01.10.2013)
Published in Nature medicine (01.10.2013)
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Journal Article
Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin
Wu, Colleen, Rankin, Erinn B, Castellini, Laura, Alcudia, Javier F, Fernandez-Alcudia, Javier, LaGory, Edward L, Andersen, Rebecca, Rhodes, Steven D, Wilson, Tremika L S, Mohammad, Khalid S, Castillo, Alesha B, Guise, Theresa A, Schipani, Ernestina, Giaccia, Amato J
Published in Genes & development (15.04.2015)
Published in Genes & development (15.04.2015)
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Journal Article
NLRP10 maintains epidermal homeostasis by promoting keratinocyte survival and P63-dependent differentiation and barrier function
Cho, Yeonhee, Cao, Zhongzheng, Luo, Xin, Tian, Jennifer J., Hukkanen, Renee R., Hussien, Rajaa, Cancilla, Belinda, Chowdhury, Priyanka, Li, Fei, Ma, Shining, LaGory, Edward L., Schroeder, Mark, Dusenberry, Amanda, Marshall, Leslie, Hawkins, Jenn, van Lookeren Campagne, Menno, Zhou, Yi
Published in Cell death & disease (18.10.2024)
Published in Cell death & disease (18.10.2024)
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Journal Article
Analysis of p53 Transactivation Domain Mutants Reveals Acad11 as a Metabolic Target Important for p53 Pro-Survival Function
Jiang, Dadi, LaGory, Edward L., Kenzelmann Brož, Daniela, Bieging, Kathryn T., Brady, Colleen A., Link, Nichole, Abrams, John M., Giaccia, Amato J., Attardi, Laura D.
Published in Cell reports (Cambridge) (24.02.2015)
Published in Cell reports (Cambridge) (24.02.2015)
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Journal Article
Rapid depletion of "catch-and-release" anti-ASGR1 antibody in vivo
Devanaboyina, Siva Charan, Li, Peng, LaGory, Edward L, Poon-Andersen, Carrie, Cook, Kevin D, Soto, Marcus, Wang, Zhe, Dang, Khue, Uyeda, Craig, Case, Ryan B, Thomas, Veena A, Primack, Ronya, Ponce, Manuel, Di, Mei, Ouyang, Brian, Kaner, Joelle, Lam, Sheung Kwan, Mostafavi, Mina
Published in mAbs (31.12.2024)
Published in mAbs (31.12.2024)
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Journal Article
Mitochondrial copper depletion suppresses triple-negative breast cancer in mice
Cui, Liyang, Gouw, Arvin M., LaGory, Edward L., Guo, Shenghao, Attarwala, Nabeel, Tang, Yao, Qi, Ji, Chen, Yun-Sheng, Gao, Zhou, Casey, Kerriann M., Bazhin, Arkadiy A., Chen, Min, Hu, Leeann, Xie, Jinghang, Fang, Mingxi, Zhang, Cissy, Zhu, Qihua, Wang, Zhiyuan, Giaccia, Amato J., Gambhir, Sanjiv Sam, Zhu, Weiping, Felsher, Dean W., Pegram, Mark D., Goun, Elena A., Le, Anne, Rao, Jianghong
Published in Nature biotechnology (01.03.2021)
Published in Nature biotechnology (01.03.2021)
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Journal Article
Suppression of PGC-1a Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma
LaGory, Edward L., Wu, Colleen, Taniguchi, Cullen M., Ding, Chien-Kuang Cornelia, Chi, Jen-Tsan, von Eyben, Rie, Scott, David A., Richardson, Adam D., Giaccia, Amato J.
Published in Cell reports (Cambridge) (28.07.2015)
Published in Cell reports (Cambridge) (28.07.2015)
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Journal Article
Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate
Yao, Qing, Khan, Mohd Parvez, Merceron, Christophe, LaGory, Edward L., Tata, Zachary, Mangiavini, Laura, Hu, Jiarui, Vemulapalli, Krishna, Chandel, Navdeep S., Giaccia, Amato J., Schipani, Ernestina
Published in Developmental cell (03.06.2019)
Published in Developmental cell (03.06.2019)
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Journal Article
An activatable NIR fluorescent rosol for selectively imaging nitroreductase activity
Klockow, Jessica L., Hettie, Kenneth S., LaGory, Edward L., Moon, Eui Jung, Giaccia, Amato J., Graves, Edward E., Chin, Frederick T.
Published in Sensors and actuators. B, Chemical (01.03.2020)
Published in Sensors and actuators. B, Chemical (01.03.2020)
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Journal Article
Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy
Chang, Alex Chia Yu, Ong, Sang-Ging, LaGory, Edward L., Kraft, Peggy E., Giaccia, Amato J., Wu, Joseph C., Blau, Helen M.
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (15.11.2016)
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Journal Article
Cellular Neonatal Fc Receptor Recycling Efficiencies can Differentiate Target-Independent Clearance Mechanisms of Monoclonal Antibodies
Bryniarski, Mark A., Tuhin, Md Tariqul Haque, Acker, Timothy M., Wakefield, Devin L., Sethaputra, Panijaya (Gemy), Cook, Kevin D., Soto, Marcus, Ponce, Manuel, Primack, Ronya, Jagarapu, Aditya, LaGory, Edward L., Conner, Kip P.
Published in Journal of pharmaceutical sciences (01.09.2024)
Published in Journal of pharmaceutical sciences (01.09.2024)
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Journal Article
Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia
Li, Yang, Gruber, Joshua J., Litzenburger, Ulrike M., Zhou, Yiren, Miao, Yu Rebecca, LaGory, Edward L., Li, Albert M., Hu, Zhen, Yip, Michaela, Hart, Lori S., Maris, John M., Chang, Howard Y., Giaccia, Amato J., Ye, Jiangbin
Published in Cell death & disease (06.02.2020)
Published in Cell death & disease (06.02.2020)
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Journal Article