Kinase selectivity potential for inhibitors targeting the ATP binding site: a network analysis
Huang, Danzhi, Zhou, Ting, Lafleur, Karine, Nevado, Cristina, Caflisch, Amedeo
Published in Bioinformatics (15.01.2010)
Published in Bioinformatics (15.01.2010)
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Journal Article
Optimization of Inhibitors of the Tyrosine Kinase EphB4. 2. Cellular Potency Improvement and Binding Mode Validation by X‑ray Crystallography
Lafleur, Karine, Dong, Jing, Huang, Danzhi, Caflisch, Amedeo, Nevado, Cristina
Published in Journal of medicinal chemistry (10.01.2013)
Published in Journal of medicinal chemistry (10.01.2013)
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Journal Article
Pyrrolo[3,2-b]quinoxaline Derivatives as Types I-1/2 and II Eph Tyrosine Kinase Inhibitors: Structure-Based Design, Synthesis, and in Vivo Validation
Unzue, Andrea, Dong, Jing, Lafleur, Karine, Zhao, Hongtao, Frugier, Emilie, Caflisch, Amedeo, Nevado, Cristina
Published in Journal of medicinal chemistry (14.08.2014)
Published in Journal of medicinal chemistry (14.08.2014)
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Journal Article
Structure-Based Optimization of Potent and Selective Inhibitors of the Tyrosine Kinase Erythropoietin Producing Human Hepatocellular Carcinoma Receptor B4 (EphB4)
Lafleur, Karine, Huang, Danzhi, Zhou, Ting, Caflisch, Amedeo, Nevado, Cristina
Published in Journal of medicinal chemistry (22.10.2009)
Published in Journal of medicinal chemistry (22.10.2009)
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Journal Article
Pyrrolo[3,2‑b]quinoxaline Derivatives as Types I1/2 and II Eph Tyrosine Kinase Inhibitors: Structure-Based Design, Synthesis, and in Vivo Validation
Unzue, Andrea, Dong, Jing, Lafleur, Karine, Zhao, Hongtao, Frugier, Emilie, Caflisch, Amedeo, Nevado, Cristina
Published in Journal of medicinal chemistry (14.08.2014)
Published in Journal of medicinal chemistry (14.08.2014)
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Journal Article
Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation
Unzue, Andrea, Lafleur, Karine, Zhao, Hongtao, Zhou, Ting, Dong, Jing, Kolb, Peter, Liebl, Johanna, Zahler, Stefan, Caflisch, Amedeo, Nevado, Cristina
Published in European journal of medicinal chemistry (13.04.2016)
Published in European journal of medicinal chemistry (13.04.2016)
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Journal Article
Complementing ultrafast shape recognition with an optical isomerism descriptor
Zhou, Ting, Lafleur, Karine, Caflisch, Amedeo
Published in Journal of molecular graphics & modelling (01.11.2010)
Published in Journal of molecular graphics & modelling (01.11.2010)
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Journal Article
Students' Motivations for Voluntary Remedial Learning in High School
Pelletier, Daniel, Green-Demers, Isabelle, Lafleur, Karine
Published in Journal of international education research (29.09.2013)
Published in Journal of international education research (29.09.2013)
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Journal Article
ChemInform Abstract: Three Stories on Eph Kinase Inhibitors: From in silico Discovery to in vivo Validation
Unzue, Andrea, Lafleur, Karine, Zhao, Hongtao, Zhou, Ting, Dong, Jing, Kolb, Peter, Liebl, Johanna, Zahler, Stefan, Caflisch, Amedeo, Nevado, Cristina
Published in ChemInform (01.03.2016)
Published in ChemInform (01.03.2016)
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Journal Article
Anti-angiogenic compounds
HUANG DANZHI, CAFLISCH AMEDEO, LAFLEUR KARINE, KOLB PETER, NEVADO CRISTINA
Year of Publication 01.07.2014
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Year of Publication 01.07.2014
Patent
2-AMINO-1-(O-TOLYL)PYRROLO[3,2-B]QUINOXALINE-3-CARBOXAMIDE DERIVATES
NEVADO BLAZQUEZ, CRISTINA, ZHAO, HONGTAO, FRUGIER, EMILIE, LAFLEUR, KARINE ANNE, HUANG, DANZHI, UNZUE LOPEZ, ANDREA, CAFLISCH, AMEDEO
Year of Publication 30.12.2015
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Year of Publication 30.12.2015
Patent
2-AMINO-1-(O-TOLYL)PYRROLO[3,2-B]QUINOXALINE-3-CARBOXAMIDE DERIVATES
NEVADO BLAZQUEZ, CRISTINA, ZHAO, HONGTAO, FRUGIER, EMILIE, LAFLEUR, KARINE ANNE, HUANG, DANZHI, UNZUE LOPEZ, ANDREA, CAFLISCH, AMEDEO
Year of Publication 01.10.2015
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Year of Publication 01.10.2015
Patent
2-AMINO-1-PHENYL-PYRROLO[3,2-B]QUINOXALINE-3-CARBOXAMIDE DERIVATES
ZHAO, HONGTAO, NEVADO BLAZQUEZ, CRISTINA, FRUGIER, EMILIE, LAFLEUR, KARINE ANNE, DONG, JING, UNZUE LOPEZ, ANDREA, CAFLISCH, AMEDEO
Year of Publication 01.10.2015
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Year of Publication 01.10.2015
Patent
2-Amino-1-(o-tolyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide derivates
ZHAO, HONGTAO, NEVADO BLAZQUEZ, CRISTINA, LAFLEUR, KARINE ANNE, FRUGIER, EMILIE, HUANG, DANZHI, UNZUE LOPEZ, ANDREA, CAFLISCH, AMEDEO
Year of Publication 30.09.2015
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Year of Publication 30.09.2015
Patent
2-Amino-1-phenyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide derivates
ZHAO, HONGTAO, NEVADO BLAZQUEZ, CRISTINA, LAFLEUR, KARINE ANNE, FRUGIER, EMILIE, DONG, JING, UNZUE LOPEZ, ANDREA, CAFLISCH, AMEDEO
Year of Publication 30.09.2015
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Year of Publication 30.09.2015
Patent
ANTI-ANGIOGENIC COMPOUNDS
HUANG DANZHI, CAFLISCH AMEDEO, LAFLEUR KARINE, KOLB PETER, NEVADO CRISTINA
Year of Publication 31.03.2011
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Year of Publication 31.03.2011
Patent
ANTI-ANGIOGENIC COMPOUNDS
HUANG, DANZHI, KOLB, PETER, LAFLEUR, KARINE, CAFLISCH, AMEDEO, NEVADO, CRISTINA
Year of Publication 02.09.2010
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Year of Publication 02.09.2010
Patent