Pathway analysis of senescence-associated miRNA targets reveals common processes to different senescence induction mechanisms
Lafferty-Whyte, Kyle, Cairney, Claire J., Jamieson, Nigel B., Oien, Karin A., Keith, W. Nicol
Published in Biochimica et biophysica acta (01.04.2009)
Published in Biochimica et biophysica acta (01.04.2009)
Get full text
Journal Article
Loss of E-cadherin disrupts ovarian epithelial inclusion cyst formation and collective cell movement in ovarian cancer cells
Choi, Pui-Wah, Yang, Junzheng, Ng, Shu-Kay, Feltmate, Colleen, Muto, Michael G, Hasselblatt, Kathleen, Lafferty-Whyte, Kyle, JeBailey, Lellean, MacConaill, Laura, Welch, William R, Fong, Wing-Ping, Berkowitz, Ross S, Ng, Shu-Wing
Published in Oncotarget (26.01.2016)
Published in Oncotarget (26.01.2016)
Get full text
Journal Article
Telomerase upregulation is a postcrisis event during senescence bypass and immortalization of two Nijmegen breakage syndrome T cell cultures
Degerman, Sofie, Siwicki, Jan Konrad, Osterman, Pia, Lafferty‐Whyte, Kyle, Keith, W. Nicol, Roos, Göran
Published in Aging cell (01.04.2010)
Published in Aging cell (01.04.2010)
Get full text
Journal Article
Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival advantage in peritoneal mesothelioma
Lafferty-Whyte, Kyle, Bilsland, Alan, Cairney, Claire J, Hanley, Lorna, Jamieson, Nigel B, Zaffaroni, Nadia, Oien, Karin A, Burns, Sharon, Roffey, Jon, Boyd, Susan M, Keith, W Nicol
Published in BMC genomics (01.10.2010)
Published in BMC genomics (01.10.2010)
Get full text
Journal Article
TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression
Lafferty-Whyte, Kyle, Bilsland, Alan, Hoare, Stacey F., Burns, Sharon, Zaffaroni, Nadia, Cairney, Claire J., Keith, William Nicol
Published in Neoplasia (New York, N.Y.) (01.05.2010)
Published in Neoplasia (New York, N.Y.) (01.05.2010)
Get full text
Journal Article
Dynamic telomerase gene suppression via network effects of GSK3 inhibition
Bilsland, Alan E, Hoare, Stacey, Stevenson, Katrina, Plumb, Jane, Gomez-Roman, Natividad, Cairney, Claire, Burns, Sharon, Lafferty-Whyte, Kyle, Roffey, Jon, Hammonds, Tim, Keith, W Nicol
Published in PloS one (31.07.2009)
Published in PloS one (31.07.2009)
Get full text
Journal Article
Trial watch: Opportunities and challenges of the 2016 target landscape
Lafferty-Whyte, Kyle, Mormeneo, David, Del Fresno Marimon, Montse
Published in Nature reviews. Drug discovery (01.01.2017)
Published in Nature reviews. Drug discovery (01.01.2017)
Get full text
Journal Article
Opportunities and challenges of the 2016 target landscape
Lafferty-Whyte, Kyle, Mormeneo, David, del Fresno Marimon, Montse
Published in Nature reviews. Drug discovery (2017)
Published in Nature reviews. Drug discovery (2017)
Get full text
Journal Article
Abstract 352: Integrating transcriptomic data using metacore pathway analysis to identify novel biomarkers of bevacizumab target engagement
Willis, Chris D., Lafferty-Whyte, Kyle, Baker, Melinda, Pestell, Richard G.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Get full text
Journal Article
A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT
Lafferty-Whyte, K, Cairney, C J, Will, M B, Serakinci, N, Daidone, M -G, Zaffaroni, N, Bilsland, A, Keith, W N
Published in Oncogene (29.10.2009)
Published in Oncogene (29.10.2009)
Get full text
Journal Article
TCEAL7 Inhibition of c-Myc Activity in Alternative Lengthening of Telomeres Regulates hTERT Expression1 2
Lafferty-Whyte, Kyle, Bilsland, Alan, Hoare, Stacey F, Burns, Sharon, Zaffaroni, Nadia, Cairney, Claire J, Keith, William Nicol
Published in Neoplasia (New York, N.Y.) (01.05.2010)
Get full text
Published in Neoplasia (New York, N.Y.) (01.05.2010)
Journal Article