Targeting fibroblast growth factor receptors to combat aggressive ependymoma
Lötsch, Daniela, Kirchhofer, Dominik, Englinger, Bernhard, Jiang, Li, Okonechnikov, Konstantin, Senfter, Daniel, Laemmerer, Anna, Gabler, Lisa, Pirker, Christine, Donson, Andrew M., Bannauer, Peter, Korbel, Pia, Jaunecker, Carola N., Hübner, Jens-Martin, Mayr, Lisa, Madlener, Sibylle, Schmook, Maria T., Ricken, Gerda, Maaß, Kendra, Grusch, Michael, Holzmann, Klaus, Grasl-Kraupp, Bettina, Spiegl-Kreinecker, Sabine, Hsu, Jennifer, Dorfer, Christian, Rössler, Karl, Azizi, Amedeo A., Foreman, Nicholas K., Peyrl, Andreas, Haberler, Christine, Czech, Thomas, Slavc, Irene, Filbin, Mariella G., Pajtler, Kristian W., Kool, Marcel, Berger, Walter, Gojo, Johannes
Published in Acta neuropathologica (01.08.2021)
Published in Acta neuropathologica (01.08.2021)
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Journal Article
A whole‐genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors
Taubenschmid‐Stowers, Jasmin, Orthofer, Michael, Laemmerer, Anna, Krauditsch, Christian, Rózsová, Marianna, Studer, Christian, Lötsch, Daniela, Gojo, Johannes, Gabler, Lisa, Dyczynski, Matheus, Efferth, Thomas, Hagelkruys, Astrid, Widhalm, Georg, Peyrl, Andreas, Spiegl‐Kreinecker, Sabine, Hoepfner, Dominic, Bian, Shan, Berger, Walter, Knoblich, Juergen A, Elling, Ulrich, Horn, Moritz, Penninger, Josef M
Published in EMBO molecular medicine (08.03.2023)
Published in EMBO molecular medicine (08.03.2023)
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Journal Article
Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness
Gabler, Lisa, Jaunecker, Carola Nadine, Katz, Sonja, van Schoonhoven, Sushilla, Englinger, Bernhard, Pirker, Christine, Mohr, Thomas, Vician, Petra, Stojanovic, Mirjana, Woitzuck, Valentin, Laemmerer, Anna, Kirchhofer, Dominik, Mayr, Lisa, LaFranca, Mery, Erhart, Friedrich, Grissenberger, Sarah, Wenninger-Weinzierl, Andrea, Sturtzel, Caterina, Kiesel, Barbara, Lang, Alexandra, Marian, Brigitte, Grasl-Kraupp, Bettina, Distel, Martin, Schüler, Julia, Gojo, Johannes, Grusch, Michael, Spiegl-Kreinecker, Sabine, Donoghue, Daniel J, Lötsch, Daniela, Berger, Walter
Published in Acta neuropathologica communications (28.04.2022)
Published in Acta neuropathologica communications (28.04.2022)
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Journal Article
Lysosomal Sequestration Impairs the Activity of the Preclinical FGFR Inhibitor PD173074
Englinger, Bernhard, Kallus, Sebastian, Senkiv, Julia, Laemmerer, Anna, Moser, Patrick, Gabler, Lisa, Groza, Diana, Kowol, Christian R, Heffeter, Petra, Grusch, Michael, Berger, Walter
Published in Cells (Basel, Switzerland) (08.12.2018)
Published in Cells (Basel, Switzerland) (08.12.2018)
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Journal Article
ATRT-12. EXPLORING FGFR INHIBITION AND COMBINATION THERAPIES FOR ATYPICAL TERATOID/RHABDOID TUMORS
Senfter, Daniel, Freund, Julia, Mager, Leah, Bruckner, Katharina, Stepien, Natalia, Mayr, Lisa, Jaunecker, Carola N, Laemmerer, Anna, Kirchhofer, Dominik, Kuess, Peter, Eckert, Franziska, Dorfer, Christian, Kool, Marcel, Haberler, Christine, Berger, Walter, Lötsch-Gojo, Daniela, Madlener, Sibylle, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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Journal Article
Nanoformulations of anticancer FGFR inhibitors with improved therapeutic index
Kallus, Sebastian, Englinger, Bernhard, Senkiv, Julia, Laemmerer, Anna, Heffeter, Petra, Berger, Walter, Kowol, Christian R., Keppler, Bernhard K.
Published in Nanomedicine (01.11.2018)
Published in Nanomedicine (01.11.2018)
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Journal Article
Lipid droplet‐mediated scavenging as novel intrinsic and adaptive resistance factor against the multikinase inhibitor ponatinib
Englinger, Bernhard, Laemmerer, Anna, Moser, Patrick, Kallus, Sebastian, Röhrl, Clemens, Pirker, Christine, Baier, Dina, Mohr, Thomas, Niederstaetter, Laura, Meier‐Menches, Samuel M., Gerner, Christopher, Gabler, Lisa, Gojo, Johannes, Timelthaler, Gerald, Senkiv, Julia, Jäger, Walter, Kowol, Christian R., Heffeter, Petra, Berger, Walter
Published in International journal of cancer (15.09.2020)
Published in International journal of cancer (15.09.2020)
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Journal Article
EPEN-10. INDUCING A SENESCENCE PHENOTYPE BY BROMODOMAIN INHIBITION IN HIGH-RISK EPENDYMOMA
Jaunecker, Carola N, Freund, Julia, Laemmerer, Anna, Roosen, Mieke, Kirchhofer, Dominik, Otto, Antonia, Madlener, Sybille, Mager, Leah, Bruckner, Katharina, Stepien, Natalia, Pirker, Christine, Gabler, Lisa, Senfter, Daniel, Jenseit, Anne, Kuess, Peter, Eckert, Franziska, Spiegl-Kreinecker, Sabine, Dorfer, Cristian, Filbin, Mariella, Kool, Marcel, Gojo, Johannes, Berger, Walter, Loetsch-Gojo, Daniela
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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Journal Article
PATH-08. PRE-OPERATIVE TUMOUR CLASSIFICATION USING NANOPORE SEQUENCING OF CEREBROSPINAL FLUID
Stepien, Natalia, Senfter, Daniel, Freund, Julia, Machreich, Sarah, Bruckner, Katharina, Mager, Leah, Laemmerer, Anna, Jaunecker, Carola, Pirker, Christine, Lötsch-Gojo, Daniela, Mayr, Lisa, Hedrich, Cora, Lippolis, Maria Aliotti, Schned, Hannah, Köller, Clara, Kiesel, Barbara, Dorfer, Christian, Azizi, Amedeo A, Peyrl, Andreas, Schmook, Maria T, Euskirchen, Philipp, Pagès-Gallego, Marc, Vermeulen, Carlo, Tops, Bastiaan, Haberler, Christine, Müllauer, Leonhard, Madlener, Sibylle, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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Journal Article
CSIG-04. UNCOUPLING OF ETS1 FROM MAPK PATHWAY SIGNALS AS RESISTANCE MECHANISM TOWARDS BRAF INHIBITORS IN BRAF-MUTATED CHILDHOOD GLIOMA
Gabler, Lisa, Lötsch-Gojo, Daniela, Kirchhofer, Dominik, Laemmerer, Anna, Mayr, Lisa, Pirker, Christine, Jaunecker, Carola, Kastler, Lucia, Azizi, Amedeo A, Dorfer, Christian, Czech, Thomas, Haberler, Christine, Peyrl, Andreas, Slavc, Irene, Spiegl-Kreinecker, Sabine, Roessler, Karl, Gojo, Johannes, Berger, Walter
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
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Journal Article
CBIO-22. PARP INHIBITION SYNERGIZES WITH DNA DAMAGING DRUGS IN PEDIATRIC CNS TUMORS
Laemmerer, Anna, Kirchhofer, Dominik, Madlener, Sibylle, Loetsch-Gojo, Daniela, Jaunecker, Carola, Schrempf, Anna, Reisecker, Johannes, Vician, Petra, Gabler, Lisa, Mayr, Lisa, Loizou, Joanna, Slavc, Irene, Berger, Walter, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
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Journal Article
EPEN-23. Interaction of epigenetic regulation and telomerase re-activation in high-risk ependymoma
Jaunecker, Carola N, Kirchhofer, Dominik, Madlener, Sibylle, Laemmerer, Anna, Gabler, Lisa, Pirker, Christine, Piontek, Martin, Maaß, Kendra, Okonechnikov, Konstanitin, Englinger, Bernhard, Jiang, Li, Mayr, Lisa, Senfter, Daniel, Spiegl-Kreinecker, Sabine, Stepien, Natalia, Dorfer, Christian, Filbin, Mariella, Kool, Marcel, Gojo, Johannes, Berger, Walter, Loetsch-Gojo, Daniela
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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Journal Article
HGG-50. Specific sensitivity of pediatric high-grade glioma with ATRX inactivation to PARP inhibitor combinations
Laemmerer, Anna, Kirchhofer, Dominik, Madlener, Sibylle, Loetsch-Gojo, Daniela, Jaunecker, Carola N, Gabler, Lisa, Mayr, Lisa, Stepien, Natalia, Baumgartner, Alicia, Dieckmann, Karin, Pfister, Stefan M, Kool, Marcel, Krausert, Sonja, Gopisetty, Apurva, Jäger, Natalie, Peyrl, Andreas, Azizi, Amedeo A, Berger, Walter, Gojo, Johannes
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
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Journal Article
Abstract 1839: Lipid metabolism as target and modulator of KP1339 anticancer activity
Baier, Dina Salome, Schoenhacker-Alte, Beatrix, Pirker, Christine, Englinger, Bernhard, Mohr, Thomas, Meier-Menches, Samuel, Roehrl, Clemens, Moser, Patrick, Laemmerer, Anna, Neuditschko, Benjamin, Niederstaetter, Laura, Brunmair, Julia, Schaier, Martin, Regner, Benedikt, Nowikovsky, Karin, Gerner, Christopher, Koellensperger, Gunda, Heffeter, Petra, Keppler, Bernhard Klaus, Berger, Walter
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 3951: Unprecedented forward genetic screens reveal mechanisms of action, drug resistances, and hidden efficacies at amino acid resolution: combination of 5-ALA and Artesunate as a treatment option for glioblastoma multiforme
Orthofer, Michael, Taubenschmid-Stowers, Jasmin, Rozsova, Marianna, Laemmerer, Anna, Loetsch, Daniela, Gojo, Johannes, Peyrl, Andreas, Berger, Walter, Elling, Ullrich, Horn, Moritz, Penninger, Josef M.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Development of a cobalt()-based ponatinib prodrug system
Mathuber, Marlene, Gutmann, Michael, La Franca, Mery, Vician, Petra, Laemmerer, Anna, Moser, Patrick, Keppler, Bernhard K, Berger, Walter, Kowol, Christian R
Published in Inorganic chemistry frontiers (30.03.2021)
Published in Inorganic chemistry frontiers (30.03.2021)
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Journal Article
Cerebrospinal Fluid Penetration and Combination Therapy of Entrectinib for Disseminated ROS1/NTRK -Fusion Positive Pediatric High-Grade Glioma
Mayr, Lisa, Guntner, Armin S, Madlener, Sibylle, Schmook, Maria T, Peyrl, Andreas, Azizi, Amedeo A, Dieckmann, Karin, Reisinger, Dominik, Stepien, Natalia M, Schramm, Kathrin, Laemmerer, Anna, Jones, David T W, Ecker, Jonas, Sahm, Felix, Milde, Till, Pajtler, Kristian W, Blattner-Johnson, Mirjam, Strbac, Miroslav, Dorfer, Christian, Czech, Thomas, Kirchhofer, Dominik, Gabler, Lisa, Berger, Walter, Haberler, Christine, Müllauer, Leonhard, Buchberger, Wolfgang, Slavc, Irene, Lötsch-Gojo, Daniela, Gojo, Johannes
Published in Journal of personalized medicine (18.12.2020)
Published in Journal of personalized medicine (18.12.2020)
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