Autophagy in Huntington disease and huntingtin in autophagy
Martin, Dale D.O, Ladha, Safia, Ehrnhoefer, Dagmar E, Hayden, Michael R
Published in Trends in neurosciences (Regular ed.) (01.01.2015)
Published in Trends in neurosciences (Regular ed.) (01.01.2015)
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Journal Article
Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice
Wong, Bibiana K.Y, Ehrnhoefer, Dagmar E, Graham, Rona K, Martin, Dale D.O, Ladha, Safia, Uribe, Valeria, Stanek, Lisa M, Franciosi, Sonia, Qiu, Xiaofan, Deng, Yu, Kovalik, Vlad, Zhang, Weining, Pouladi, Mahmoud A, Shihabuddin, Lamya S, Hayden, Michael R
Published in Neurobiology of disease (01.04.2015)
Published in Neurobiology of disease (01.04.2015)
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Journal Article
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease
Ehrnhoefer, Dagmar E, Martin, Dale D O, Schmidt, Mandi E, Qiu, Xiaofan, Ladha, Safia, Caron, Nicholas S, Skotte, Niels H, Nguyen, Yen T N, Vaid, Kuljeet, Southwell, Amber L, Engemann, Sabine, Franciosi, Sonia, Hayden, Michael R
Published in Acta neuropathologica communications (06.03.2018)
Published in Acta neuropathologica communications (06.03.2018)
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Journal Article
A quantitative method for the specific assessment of caspase-6 activity in cell culture
Ehrnhoefer, Dagmar E, Skotte, Niels H, Savill, Jane, Nguyen, Yen T N, Ladha, Safia, Cao, Li-Ping, Dullaghan, Edie, Hayden, Michael R
Published in PloS one (29.11.2011)
Published in PloS one (29.11.2011)
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Journal Article
Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound
Ehrnhoefer, Dagmar E, Skotte, Niels H, Reinshagen, Jeanette, Qiu, Xiaofan, Windshügel, Björn, Jaishankar, Priyadarshini, Ladha, Safia, Petina, Olga, Khankischpur, Mehdi, Nguyen, Yen T N, Caron, Nicholas S, Razeto, Adelia, Meyer Zu Rheda, Matthias, Deng, Yu, Huynh, Khuong T, Wittig, Ilka, Gribbon, Philip, Renslo, Adam R, Geffken, Detlef, Gul, Sheraz, Hayden, Michael R
Published in Cell chemical biology (19.09.2019)
Published in Cell chemical biology (19.09.2019)
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Journal Article
p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin
Ehrnhoefer, Dagmar E, Skotte, Niels H, Ladha, Safia, Nguyen, Yen T N, Qiu, Xiaofan, Deng, Yu, Huynh, Khuong T, Engemann, Sabine, Nielsen, Signe M, Becanovic, Kristina, Leavitt, Blair R, Hasholt, Lis, Hayden, Michael R
Published in Human molecular genetics (01.02.2014)
Published in Human molecular genetics (01.02.2014)
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Constitutive ablation of caspase-6 reduces the inflammatory response and behavioural changes caused by peripheral pro-inflammatory stimuli
Ladha, Safia, Qiu, Xiaofan, Casal, Lorenzo, Caron, Nicholas S, Ehrnhoefer, Dagmar E, Hayden, Michael R
Published in Cell death discovery (12.03.2018)
Published in Cell death discovery (12.03.2018)
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Journal Article
Feeding Schedule And Proteolysis Regulate Autophagic Clearance Of Mutant Huntingtin
Ehrnhoefer, Dagmar Elisabeth, Dale Do Martin, Qiu, Xiaofan, Ladha, Safia, Caron, Nicholas S, Skotte, Niels H, Nguyen, Yen Tn, Engemann, Sabine, Franciosi, Sonia, Hayden, Michael R
Published in bioRxiv (13.03.2017)
Published in bioRxiv (13.03.2017)
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