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Chan, Chia-Hsin, Morrow, John Kenneth, Li, Chien-Feng, Gao, Yuan, Jin, Guoxiang, Moten, Asad, Stagg, Loren J., Ladbury, John E., Cai, Zhen, Xu, Dazhi, Logothetis, Christopher J., Hung, Mien-Chie, Zhang, Shuxing, Lin, Hui-Kuan
Published in Cell (01.08.2013)
Published in Cell (01.08.2013)
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Adding calorimetric data to decision making in lead discovery: a hot tip
Ladbury, John E, Klebe, Gerhard, Freire, Ernesto
Published in Nature reviews. Drug discovery (01.01.2010)
Published in Nature reviews. Drug discovery (01.01.2010)
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Book Review
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Lin, Chi-Chuan, Melo, Fernando A., Ghosh, Ragini, Suen, Kin M., Stagg, Loren J., Kirkpatrick, John, Arold, Stefan T., Ahmed, Zamal, Ladbury, John E.
Published in Cell (22.06.2012)
Published in Cell (22.06.2012)
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Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions
Seidel, Susanne A.I., Dijkman, Patricia M., Lea, Wendy A., van den Bogaart, Geert, Jerabek-Willemsen, Moran, Lazic, Ana, Joseph, Jeremiah S., Srinivasan, Prakash, Baaske, Philipp, Simeonov, Anton, Katritch, Ilia, Melo, Fernando A., Ladbury, John E., Schreiber, Gideon, Watts, Anthony, Braun, Dieter, Duhr, Stefan
Published in Methods (San Diego, Calif.) (01.03.2013)
Published in Methods (San Diego, Calif.) (01.03.2013)
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A Landscape of Driver Mutations in Melanoma
Hodis, Eran, Watson, Ian R., Kryukov, Gregory V., Arold, Stefan T., Imielinski, Marcin, Theurillat, Jean-Philippe, Nickerson, Elizabeth, Auclair, Daniel, Li, Liren, Place, Chelsea, DiCara, Daniel, Ramos, Alex H., Lawrence, Michael S., Cibulskis, Kristian, Sivachenko, Andrey, Voet, Douglas, Saksena, Gordon, Stransky, Nicolas, Onofrio, Robert C., Winckler, Wendy, Ardlie, Kristin, Wagle, Nikhil, Wargo, Jennifer, Chong, Kelly, Morton, Donald L., Stemke-Hale, Katherine, Chen, Guo, Noble, Michael, Meyerson, Matthew, Ladbury, John E., Davies, Michael A., Gershenwald, Jeffrey E., Wagner, Stephan N., Hoon, Dave S.B., Schadendorf, Dirk, Lander, Eric S., Gabriel, Stacey B., Getz, Gad, Garraway, Levi A., Chin, Lynda
Published in Cell (20.07.2012)
Published in Cell (20.07.2012)
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TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26
Meller, Stephan, Di Domizio, Jeremy, Voo, Kui S, Friedrich, Heike C, Chamilos, Georgios, Ganguly, Dipyaman, Conrad, Curdin, Gregorio, Josh, Le Roy, Didier, Roger, Thierry, Ladbury, John E, Homey, Bernhard, Watowich, Stanley, Modlin, Robert L, Kontoyiannis, Dimitrios P, Liu, Yong-Jun, Arold, Stefan T, Gilliet, Michel
Published in Nature immunology (13.07.2015)
Published in Nature immunology (13.07.2015)
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The Thermodynamics of Protein–Ligand Interaction and Solvation: Insights for Ligand Design
Olsson, Tjelvar S.G., Williams, Mark A., Pitt, William R., Ladbury, John E.
Published in Journal of molecular biology (26.12.2008)
Published in Journal of molecular biology (26.12.2008)
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Structure and Interactions of the Human Programmed Cell Death 1 Receptor
Cheng, Xiaoxiao, Veverka, Vaclav, Radhakrishnan, Anand, Waters, Lorna C., Muskett, Frederick W., Morgan, Sara H., Huo, Jiandong, Yu, Chao, Evans, Edward J., Leslie, Alasdair J., Griffiths, Meryn, Stubberfield, Colin, Griffin, Robert, Henry, Alistair J., Jansson, Andreas, Ladbury, John E., Ikemizu, Shinji, Carr, Mark D., Davis, Simon J.
Published in The Journal of biological chemistry (26.04.2013)
Published in The Journal of biological chemistry (26.04.2013)
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Regulation of microRNA expression by the adaptor protein GRB2
Stainthorp, Amy K., Lin, Chi-Chuan, Wang, Dapeng, Medhi, Ragini, Ahmed, Zamal, Suen, Kin Man, Miska, Eric A., Whitehouse, Adrian, Ladbury, John E.
Published in Scientific reports (16.06.2023)
Published in Scientific reports (16.06.2023)
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H-NS uses an autoinhibitory conformational switch for environment-controlled gene silencing
Shahul Hameed, Umar F, Liao, Chenyi, Radhakrishnan, Anand K, Huser, Franceline, Aljedani, Safia S, Zhao, Xiaochuan, Momin, Afaque A, Melo, Fernando A, Guo, Xianrong, Brooks, Claire, Li, Yu, Cui, Xuefeng, Gao, Xin, Ladbury, John E, Jaremko, Łukasz, Jaremko, Mariusz, Li, Jianing, Arold, Stefan T
Published in Nucleic acids research (18.03.2019)
Published in Nucleic acids research (18.03.2019)
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Extent of enthalpy–entropy compensation in protein–ligand interactions
Olsson, Tjelvar S. G., Ladbury, John E., Pitt, Will R., Williams, Mark A.
Published in Protein science (01.09.2011)
Published in Protein science (01.09.2011)
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A requirement for ERK-dependent Dicer phosphorylation in coordinating oocyte-to-embryo transition in C. elegans
Drake, Melanie, Furuta, Tokiko, Suen, Kin Man, Gonzalez, Gabriel, Liu, Bin, Kalia, Awdhesh, Ladbury, John E, Fire, Andrew Z, Skeath, James B, Arur, Swathi
Published in Developmental cell (08.12.2014)
Published in Developmental cell (08.12.2014)
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Grb2 monomer–dimer equilibrium determines normal versus oncogenic function
Ahmed, Zamal, Timsah, Zahra, Suen, Kin M., Cook, Nathan P., Lee, Gilbert R., Lin, Chi-Chuan, Gagea, Mihai, Marti, Angel A., Ladbury, John E.
Published in Nature communications (24.06.2015)
Published in Nature communications (24.06.2015)
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Erythropoietin Stimulates Tumor Growth via EphB4
Pradeep, Sunila, Huang, Jie, Mora, Edna M., Nick, Alpa M., Cho, Min Soon, Wu, Sherry Y., Noh, Kyunghee, Pecot, Chad V., Rupaimoole, Rajesha, Stein, Martin A., Brock, Stephan, Wen, Yunfei, Xiong, Chiyi, Gharpure, Kshipra, Hansen, Jean M., Nagaraja, Archana S., Previs, Rebecca A., Vivas-Mejia, Pablo, Han, Hee Dong, Hu, Wei, Mangala, Lingegowda S., Zand, Behrouz, Stagg, Loren J., Ladbury, John E., Ozpolat, Bulent, Alpay, S. Neslihan, Nishimura, Masato, Stone, Rebecca L., Matsuo, Koji, Armaiz-Peña, Guillermo N., Dalton, Heather J., Danes, Christopher, Goodman, Blake, Rodriguez-Aguayo, Cristian, Kruger, Carola, Schneider, Armin, Haghpeykar, Shyon, Jaladurgam, Padmavathi, Hung, Mien-Chie, Coleman, Robert L., Liu, Jinsong, Li, Chun, Urbauer, Diana, Lopez-Berestein, Gabriel, Jackson, David B., Sood, Anil K.
Published in Cancer cell (09.11.2015)
Published in Cancer cell (09.11.2015)
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Grb2 binding induces phosphorylation-independent activation of Shp2
Lin, Chi-Chuan, Wieteska, Lukasz, Suen, Kin Man, Kalverda, Arnout P., Ahmed, Zamal, Ladbury, John E.
Published in Communications biology (01.04.2021)
Published in Communications biology (01.04.2021)
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FGFR1-mediated protocadherin-15 loading mediates cargo specificity during intraflagellar transport in inner ear hair-cell kinocilia
Honda, Akira, Kita, Tomoko, Seshadri, Shri Vidhya, Misaki, Kazuyo, Ahmed, Zamal, Ladbury, John E., Richardson, Guy P., Yonemura, Shigenobu, Ladher, Raj K.
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2018)
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