Phospholipid profiling of plasma from GW veterans and rodent models to identify potential biomarkers of Gulf War Illness
Emmerich, Tanja, Zakirova, Zuchra, Klimas, Nancy, Sullivan, Kimberly, Shetty, Ashok K, Evans, James E, Ait-Ghezala, Ghania, Laco, Gary S, Hattiangady, Bharathi, Shetty, Geetha A, Mullan, Michael, Crynen, Gogce, Abdullah, Laila, Crawford, Fiona
Published in PloS one (28.04.2017)
Published in PloS one (28.04.2017)
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Mild TBI Results in a Long-Term Decrease in Circulating Phospholipids in a Mouse Model of Injury
Emmerich, Tanja, Abdullah, Laila, Ojo, Joseph, Mouzon, Benoit, Nguyen, Thinh, Laco, Gary S., Crynen, Gogce, Evans, James E., Reed, Jon, Mullan, Michael, Crawford, Fiona
Published in Neuromolecular medicine (01.03.2017)
Published in Neuromolecular medicine (01.03.2017)
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Journal Article
Topoisomerase I inhibitors: selectivity and cellular resistance
Pommier, Yves, Pourquier, Philippe, Urasaki, Yoshimasa, Wu, Jiaxi, Laco, Gary S.
Published in Drug resistance updates (01.10.1999)
Published in Drug resistance updates (01.10.1999)
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Journal Article
Crystal Structure of Human T Cell Leukemia Virus Protease, a Novel Target for Anticancer Drug Design
Li, Mi, Laco, Gary S., Jaskolski, Mariusz, Jan Rozycki, Alexandratos, Jerry, Wlodawer, Alexander, Alla Gustchina, Davies, David R.
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (20.12.2005)
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Journal Article
Interaction of Human Nuclear Topoisomerase I with Guanosine Quartet-forming and Guanosine-rich Single-stranded DNA and RNA Oligonucleotides
Marchand, Christophe, Pourquier, Philippe, Laco, Gary S., Jing, Naijie, Pommier, Yves
Published in The Journal of biological chemistry (15.03.2002)
Published in The Journal of biological chemistry (15.03.2002)
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Journal Article
Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line
URASAKI, Yoshimasa, LACO, Gary S, POURQUIER, Phillipe, TAKEBAYASHI, Yuji, KOHLHAGEN, Glenda, GIOFFRE, Christopher, HONGLIANG ZHANG, CHATTERJEE, Devasis, PANTAZIS, Panayotis, POMMIER, Yves
Published in Cancer research (Chicago, Ill.) (01.03.2001)
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Published in Cancer research (Chicago, Ill.) (01.03.2001)
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Position-Specific Trapping of Topoisomerase I-DNA Cleavage Complexes by Intercalated Benzo[a]-Pyrene Diol Epoxide Adducts at the 6-Amino Group of Adenine
Pommier, Yves, Laco, Gary S., Kohlhagen, Glenda, Sayer, Jane M., Kroth, Heiko, Jerina, Donald M.
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2000)
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Different Effects on Human Topoisomerase I by Minor Groove and Intercalated Deoxyguanosine Adducts Derived from Two Polycyclic Aromatic Hydrocarbon Diol Epoxides at or Near a Normal Cleavage Site
Pommier, Yves, Kohlhagen, Glenda, Laco, Gary S., Kroth, Heiko, Sayer, Jane M., Jerina, Donald M.
Published in The Journal of biological chemistry (19.04.2002)
Published in The Journal of biological chemistry (19.04.2002)
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Journal Article
Phosphorylation of DNA Topoisomerase I by the c-Abl Tyrosine Kinase Confers Camptothecin Sensitivity
Yu, Donghui, Khan, Ehsan, Khaleque, Md Abdul, Lee, James, Laco, Gary, Kohlhagen, Glenda, Kharbanda, Surender, Cheng, Yung-Chi, Pommier, Yves, Bharti, Ajit
Published in The Journal of biological chemistry (10.12.2004)
Published in The Journal of biological chemistry (10.12.2004)
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Analysis of the S3 and S3′Subsite Specificities of Feline Immunodeficiency Virus (FIV) Protease: Development of a Broad-Based Protease Inhibitor Efficacious against FIV, SIV, and HIV in vitro and ex vivo
Lee, Taekyu, Laco, Gary S., Torbett, Bruce E., Fox, Howard S., Lerner, Danica L., Elder, John H., Wong, Chi-Huey
Published in Proceedings of the National Academy of Sciences - PNAS (03.02.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (03.02.1998)
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Journal Article
Activation of Camptothecin Derivatives by Conjugation to Triple Helix-Forming Oligonucleotides
Arimondo, Paola B, Laco, Gary S, Thomas, Craig J, Halby, Ludovic, Pez, Didier, Schmitt, Philippe, Boutorine, Alexandre, Garestier, Thérèse, Pommier, Yves, Hecht, Sidney M, Sun, Jian-Sheng, Bailly, Christian
Published in Biochemistry (Easton) (22.03.2005)
Published in Biochemistry (Easton) (22.03.2005)
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Analysis of human topoisomerase I inhibition and interaction with the cleavage site +1 deoxyguanosine, via in vitro experiments and molecular modeling studies
Laco, Gary S., Du, Wu, Kohlhagen, Glenda, Sayer, Jane M., Jerina, Donald M., Burke, Thomas G., Curran, Dennis P., Pommier, Yves
Published in Bioorganic & medicinal chemistry (01.10.2004)
Published in Bioorganic & medicinal chemistry (01.10.2004)
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Journal Article
The Spleen Tyrosine Kinase (Syk) Regulates Alzheimer Amyloid-β Production and Tau Hyperphosphorylation
Paris, Daniel, Ait-Ghezala, Ghania, Bachmeier, Corbin, Laco, Gary, Beaulieu-Abdelahad, David, Lin, Yong, Jin, Chao, Crawford, Fiona, Mullan, Michael
Published in The Journal of biological chemistry (05.12.2014)
Published in The Journal of biological chemistry (05.12.2014)
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Journal Article
Crystal Structures of the Inactive D30N Mutant of Feline Immunodeficiency Virus Protease Complexed with a Substrate and an Inhibitor
Laco, Gary S, Schalk-Hihi, Céline, Lubkowski, Jacek, Morris, Garrett, Zdanov, Alexander, Olson, Arthur, Elder, John H, Wlodawer, Alexander, Gustchina, Alla
Published in Biochemistry (Easton) (02.09.1997)
Published in Biochemistry (Easton) (02.09.1997)
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