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Derivation of cutoffs for the Elecsys® amyloid β (1–42) assay in Alzheimer's disease
Shaw, Leslie M., Waligorska, Teresa, Fields, Leona, Korecka, Magdalena, Figurski, Michal, Trojanowski, John Q., Eichenlaub, Udo, Wahl, Simone, Quan, Marian, Pontecorvo, Michael J., Lachno, D. Richard, Talbot, Jayne A., Andersen, Scott W., Siemers, Eric R., Dean, Robert A.
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2018)
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2018)
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Pharmacodynamics and pharmacokinetics of single doses of prasugrel 30 mg and clopidogrel 300 mg in healthy chinese and white volunteers: An open-label trial
Small, David S., Payne, Christopher D., Kothare, Prajakti, Yuen, Eunice, Natanegara, Fanni, Teng Loh, Mei, Jakubowski, Joseph A., Richard Lachno, D., Li, Ying G., Winters, Kenneth J., Farid, Nagy A., Ni, Lan, Salazar, Daniel E., Tomlin, Molly, Kelly, Ronan
Published in Clinical therapeutics (01.02.2010)
Published in Clinical therapeutics (01.02.2010)
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Validation of a multiplex assay for simultaneous quantification of amyloid-β peptide species in human plasma with utility for measurements in studies of Alzheimer's disease therapeutics
Lachno, D Richard, Emerson, Julie K, Vanderstichele, Hugo, Gonzales, Celedon, Martényi, Ferenc, Konrad, Robert J, Talbot, Jayne A, Lowe, Stephen L, Oefinger, Paul E, Dean, Robert A
Published in Journal of Alzheimer's disease (01.01.2012)
Published in Journal of Alzheimer's disease (01.01.2012)
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A digital enzyme-linked immunosorbent assay for ultrasensitive measurement of amyloid-β 1–42 peptide in human plasma with utility for studies of Alzheimer’s disease therapeutics
Song, Linan, Lachno, D. Richard, Hanlon, David, Shepro, Adam, Jeromin, Andreas, Gemani, Dipika, Talbot, Jayne A., Racke, Margaret M., Dage, Jeffrey L., Dean, Robert A.
Published in Alzheimer's research & therapy (15.12.2016)
Published in Alzheimer's research & therapy (15.12.2016)
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Dihydroxyphenylglycol as a Biomarker of Norepinephrine Transporter Inhibition by Atomoxetine: Human Model to Assess Central and Peripheral Effects of Dosing
Bieck, Peter R, Leibowitz, Mark, Lachno, D Richard, Ledent, Edouard, Padich, Robert, Jhee, Stan
Published in Journal of clinical psychopharmacology (01.12.2016)
Published in Journal of clinical psychopharmacology (01.12.2016)
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Recommendations for Adaptation and Validation of Commercial Kits for Biomarker Quantification in Drug Development
Khan, Masood U, Bowsher, Ronald R, Cameron, Mark, Devanarayan, Viswanath, Keller, Steve, King, Lindsay, Lee, Jean, Morimoto, Alyssa, Rhyne, Paul, Stephen, Laurie, Wu, Yuling, Wyant, Timothy, Lachno, D Richard
Published in Bioanalysis (01.01.2015)
Published in Bioanalysis (01.01.2015)
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Validation and Clinical Utility of ELISA Methods for Quantification of Amyloid-β of Peptides in Cerebrospinal Fluid Specimens from Alzheimer’s Disease Studies
Lachno, D Richard, Evert, Barbara A, Maloney, Kaia, Willis, Brian A, Talbot, Jayne A, Vandijck, Manu, Dean, Robert A
Published in Journal of Alzheimer's disease (01.01.2015)
Published in Journal of Alzheimer's disease (01.01.2015)
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A phase 1 study of prasugrel in patients with sickle cell disease: Effects on biomarkers of platelet activation and coagulation
Jakubowski, Joseph A., Zhou, Chunmei, Jurcevic, Stipo, Winters, Kenneth J., Lachno, D. Richard, Frelinger, Andrew L., Gupta, Neehar, Howard, Jo, Payne, Christopher D., Mant, Timothy G.
Published in Thrombosis research (01.02.2014)
Published in Thrombosis research (01.02.2014)
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pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects
Small, David S, Kothare, Prajakti, Yuen, Eunice, Lachno, D. Richard, Li, Ying G, Winters, Kenneth J, Farid, Nagy A, Ni, Lan, Jakubowski, Joseph A, Salazar, Daniel E, Thieu, Vivian T, Payne, Christopher D
Published in European journal of clinical pharmacology (01.02.2010)
Published in European journal of clinical pharmacology (01.02.2010)
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Effects of duloxetine on norepinephrine and serotonin transporter activity in healthy subjects
Chappell, Jill C, Eisenhofer, Graeme, Owens, Michael J, Haber, Harry, Lachno, D Richard, Dean, Robert A, Knadler, Mary Pat, Nemeroff, Charles B, Mitchell, Malcolm I, Detke, Michael J, Iyengar, Smriti, Pangallo, Beth, Lobo, Evelyn D
Published in Journal of clinical psychopharmacology (01.02.2014)
Published in Journal of clinical psychopharmacology (01.02.2014)
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A phase 1 study of prasugrel in patients with sickle cell disease: pharmacokinetics and effects on ex vivo platelet reactivity
Jakubowski, Joseph A., Zhou, Chunmei, Small, David S., Winters, Kenneth J., Lachno, D. Richard, Frelinger, Andrew L., Howard, Jo, Mant, Timothy G., Jurcevic, Stipo, Payne, Christopher D.
Published in British journal of clinical pharmacology (01.06.2013)
Published in British journal of clinical pharmacology (01.06.2013)
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Central pharmacodynamic activity of solanezumab in mild Alzheimer's disease dementia
Willis, Brian A., Sundell, Karen, Lachno, D. Richard, Ferguson-Sells, Lisa R., Case, Michael G., Holdridge, Karen, DeMattos, Ronald B., Raskin, Joel, Siemers, Eric R., Dean, Robert A.
Published in Alzheimer's & dementia : translational research & clinical interventions (2018)
Published in Alzheimer's & dementia : translational research & clinical interventions (2018)
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Pharmacokinetics and Pharmacodynamics of Edivoxetine (LY2216684), a Norepinephrine Reuptake Inhibitor, in Pediatric Patients with Attention-Deficit/ Hyperactivity Disorder
Kielbasa, William, Quinlan, Tonya, Jin, Ling, Xu, Wen, Lachno, D. Richard, Dean, Robert A., Allen, Albert J.
Published in Journal of child and adolescent psychopharmacology (01.08.2012)
Published in Journal of child and adolescent psychopharmacology (01.08.2012)
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Validation of assays for measurement of amyloid-β peptides in cerebrospinal fluid and plasma specimens from patients with Alzheimer's disease treated with solanezumab
Lachno, D Richard, Evert, Barbara A, Vanderstichele, Hugo, Robertson, Michael, Demattos, Ronald B, Konrad, Robert J, Talbot, Jayne A, Racke, Margaret M, Dean, Robert A
Published in Journal of Alzheimer's disease (01.01.2013)
Published in Journal of Alzheimer's disease (01.01.2013)
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The effect of prasugrel on ADP-stimulated markers of platelet activation in patients with sickle cell disease
Jakubowski, Joseph A., Zhou, Chunmei, Winters, Kenneth J., Lachno, D. Richard, Howard, Jo, Payne, Christopher D., Mant, Timothy, Jurcevic, Stipo, Frelinger, Andrew L.
Published in Platelets (Edinburgh) (04.07.2015)
Published in Platelets (Edinburgh) (04.07.2015)
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Dose-dependent inhibition of human platelet aggregation by prasugrel and its interaction with aspirin in healthy subjects
Jakubowski, Joseph A, Payne, Christopher D, Weerakkody, Govinda J, Brandt, John T, Farid, Nagy A, Li, Ying G, Naganuma, Hideo, Lachno, D Richard, Winters, Kenneth J
Published in Journal of cardiovascular pharmacology (01.03.2007)
Published in Journal of cardiovascular pharmacology (01.03.2007)
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Changes of urine dihydroxyphenylglycol to norepinephrine ratio in children with attention-deficit hyperactivity disorder (ADHD) treated with atomoxetine
Montoya, Alonso, Escobar, Rodrigo, García-Polavieja, María J, Lachno, D Richard, Alda, José Ángel, Artigas, Josep, Cardo, Esther, García, Marta, Gastaminza, Xavier, Gilaberte, Inmaculada
Published in Journal of child neurology (01.01.2011)
Published in Journal of child neurology (01.01.2011)
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Altered sympathoadrenal response to dynamic exercise in cardiac transplant recipients
BANNER, NICHOLAS R, PATEL, NAINA, COX, ANDREW P, PATTON, HELEN E, LACHNO, D RICHARD, YACOUB, MAGDI H
Published in Cardiovascular research (01.11.1989)
Published in Cardiovascular research (01.11.1989)
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A Phase 1 Study of Prasugrel in Subjects with Sickle Cell Disease: Impact on Ex Vivo Platelet Reactivity
Jakubowski, Joseph A., Zhou, Chunmei, Small, David S., Winters, Kenneth J., Lachno, D. Richard, Frelinger, Andrew L., Howard, Jo, Jurcevic, Stipo, Payne, Christopher D.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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A Phase 1 Study of Prasugrel in Subjects with Sickle Cell Disease: Effects on In Vivo Markers of Platelet Activation and of Coagulation
Jakubowski, Joseph A., Zhou, Chunmei, Small, David S., Winters, Kenneth J., Lachno, D. Richard, Frelinger, Andrew L., Howard, Jo, Jurcevic, Stipo, Payne, Christopher D.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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