Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection
Brown, Aisling F, Murphy, Alison G, Lalor, Stephen J, Leech, John M, O'Keeffe, Kate M, Mac Aogáin, Micheál, O'Halloran, Dara P, Lacey, Keenan A, Tavakol, Mehri, Hearnden, Claire H, Fitzgerald-Hughes, Deirdre, Humphreys, Hilary, Fennell, Jérôme P, van Wamel, Willem J, Foster, Timothy J, Geoghegan, Joan A, Lavelle, Ed C, Rogers, Thomas R, McLoughlin, Rachel M
Published in PLoS pathogens (01.11.2015)
Published in PLoS pathogens (01.11.2015)
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The cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors
Zheng, Xuhui, Marsman, Gerben, Lacey, Keenan A., Chapman, Jessica R., Goosmann, Christian, Ueberheide, Beatrix M., Torres, Victor J.
Published in Nature communications (26.10.2021)
Published in Nature communications (26.10.2021)
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Histone H1 kills MRSA
Marsman, Gerben, Zheng, Xuhui, Čerina, Dora, Lacey, Keenan A., Liu, Menghan, Humme, Daniel, Goosmann, Christian, Brinkmann, Volker, Harbort, C.J., Torres, Victor J., Zychlinsky, Arturo
Published in Cell reports (Cambridge) (26.11.2024)
Published in Cell reports (Cambridge) (26.11.2024)
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The Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine Antigens
Lacey, Keenan A, Geoghegan, Joan A, McLoughlin, Rachel M
Published in Pathogens (Basel) (17.02.2016)
Published in Pathogens (Basel) (17.02.2016)
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Microbiome-Independent Effects of Antibiotics in a Murine Model of Nosocomial Infections
Lacey, Keenan A, Gonzalez, Sandra, Yeung, Frank, Putzel, Gregory, Podkowik, Magdalena, Pironti, Alejandro, Shopsin, Bo, Cadwell, Ken, Torres, Victor J
Published in mBio (28.06.2022)
Published in mBio (28.06.2022)
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Capsular Polysaccharide Is Essential for the Virulence of the Antimicrobial-Resistant Pathogen Enterobacter hormaechei
St John, Amelia, Perault, Andrew I, Giacometti, Sabrina I, Sommerfield, Alexis G, DuMont, Ashley L, Lacey, Keenan A, Zheng, Xuhui, Sproch, Julia, Petzold, Chris, Dancel-Manning, Kristen, Gonzalez, Sandra, Annavajhala, Medini, Beckford, Colleen, Zeitouni, Nathalie, Liang, Feng-Xia, van Bakel, Harm, Shopsin, Bo, Uhlemann, Anne-Catrin, Pironti, Alejandro, Torres, Victor J
Published in mBio (25.04.2023)
Published in mBio (25.04.2023)
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Secreted mammalian DNases protect against systemic bacterial infection by digesting biofilms
Lacey, Keenan A, Serpas, Lee, Makita, Sohei, Wang, Yueyang, Rashidfarrokhi, Ali, Soni, Chetna, Gonzalez, Sandra, Moreira, Andre, Torres, Victor J, Reizis, Boris
Published in The Journal of experimental medicine (05.06.2023)
Published in The Journal of experimental medicine (05.06.2023)
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Identification of a domain critical for Staphylococcus aureus LukED receptor targeting and lysis of erythrocytes
Vasquez, Marilyn T., Lubkin, Ashira, Reyes-Robles, Tamara, Day, Christopher J., Lacey, Keenan A., Jennings, Michael P., Torres, Victor J.
Published in The Journal of biological chemistry (11.12.2020)
Published in The Journal of biological chemistry (11.12.2020)
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Staphylococcus aureus induces a muted host response in human blood that blunts the recruitment of neutrophils
Zwack, Erin E, Chen, Ze, Devlin, Joseph C, Li, Zhi, Zheng, Xuhui, Weinstock, Ada, Lacey, Keenan A, Fisher, Edward A, Fenyö, David, Ruggles, Kelly V, Loke, P'ng, Torres, Victor J
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (02.08.2022)
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Targeting leukocidin-mediated immune evasion protects mice from Staphylococcus aureus bacteremia
Tam, Kayan, Lacey, Keenan A, Devlin, Joseph C, Coffre, Maryaline, Sommerfield, Alexis, Chan, Rita, O'Malley, Aidan, Koralov, Sergei B, Loke, P'ng, Torres, Victor J
Published in The Journal of experimental medicine (07.09.2020)
Published in The Journal of experimental medicine (07.09.2020)
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Human OTULIN haploinsufficiency impairs cell-intrinsic immunity to staphylococcal α-toxin
Spaan, András N, Neehus, Anna-Lena, Laplantine, Emmanuel, Staels, Frederik, Ogishi, Masato, Seeleuthner, Yoann, Rapaport, Franck, Lacey, Keenan A, Van Nieuwenhove, Erika, Chrabieh, Maya, Hum, David, Migaud, Mélanie, Izmiryan, Araksya, Lorenzo, Lazaro, Kochetkov, Tatiana, Heesterbeek, Dani A C, Bardoel, Bart W, DuMont, Ashley L, Dobbs, Kerry, Chardonnet, Solenne, Heissel, Søren, Baslan, Timour, Zhang, Peng, Yang, Rui, Bogunovic, Dusan, Wunderink, Herman F, Haas, Pieter-Jan A, Molina, Henrik, Van Buggenhout, Griet, Lyonnet, Stanislas, Notarangelo, Luigi D, Seppänen, Mikko R J, Weil, Robert, Seminario, Gisela, Gomez-Tello, Héctor, Wouters, Carine, Mesdaghi, Mehrnaz, Shahrooei, Mohammad, Bossuyt, Xavier, Sag, Erdal, Topaloglu, Rezan, Ozen, Seza, Leavis, Helen L, van Eijk, Maarten M J, Bezrodnik, Liliana, Blancas Galicia, Lizbeth, Hovnanian, Alain, Nassif, Aude, Bader-Meunier, Brigitte, Neven, Bénédicte, Meyts, Isabelle, Schrijvers, Rik, Puel, Anne, Bustamante, Jacinta, Aksentijevich, Ivona, Kastner, Daniel L, Torres, Victor J, Humblet-Baron, Stéphanie, Liston, Adrian, Abel, Laurent, Boisson, Bertrand, Casanova, Jean-Laurent
Published in Science (American Association for the Advancement of Science) (17.06.2022)
Published in Science (American Association for the Advancement of Science) (17.06.2022)
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Single-Cell Analysis of CX3CR1+ Cells Reveals a Pathogenic Role for BIRC5+ Myeloid Proliferating Cells Driven by Staphylococcus aureus Leukotoxins
Loredan, Denis G, Devlin, Joseph C, Lacey, Keenan A, Howard, Nina, Chen, Ze, Zwack, Erin E, Lin, Jian-Da, Ruggles, Kelly V, Khanna, Kamal M, Torres, Victor J, Loke, P'ng
Published in The Journal of immunology (1950) (01.09.2023)
Published in The Journal of immunology (1950) (01.09.2023)
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The tempo and mode of gene regulatory programs during bacterial infection
Avital, Gal, Kuperwaser, Felicia, Pountain, Andrew W., Lacey, Keenan A., Zwack, Erin E., Podkowik, Magdalena, Shopsin, Bo, Torres, Victor J., Yanai, Itai
Published in Cell reports (Cambridge) (11.10.2022)
Published in Cell reports (Cambridge) (11.10.2022)
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Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections
Buckley, Peter T., Chan, Rita, Fernandez, Jeffrey, Luo, Jinquan, Lacey, Keenan A., DuMont, Ashley L., O’Malley, Aidan, Brezski, Randall J., Zheng, Songmao, Malia, Thomas, Whitaker, Brian, Zwolak, Adam, Payne, Angela, Clark, Desmond, Sigg, Martin, Lacy, Eilyn R., Kornilova, Anna, Kwok, Debra, McCarthy, Steve, Wu, Bingyuan, Morrow, Brian, Nemeth-Seay, Jennifer, Petley, Ted, Wu, Sam, Strohl, William R., Lynch, Anthony Simon, Torres, Victor J.
Published in Cell host & microbe (10.05.2023)
Published in Cell host & microbe (10.05.2023)
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A Small Membrane Stabilizing Protein Critical to the Pathogenicity of Staphylococcus aureus
Duggan, Seána, Laabei, Maisem, Alnahari, Alaa Abdulaziz, O'Brien, Eóin C, Lacey, Keenan A, Bacon, Leann, Heesom, Kate, Fu, Chih-Lung, Otto, Michael, Skaar, Eric, McLoughlin, Rachel M, Massey, Ruth C
Published in Infection and immunity (19.08.2020)
Published in Infection and immunity (19.08.2020)
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Rewilding of laboratory mice enhances granulopoiesis and immunity through intestinal fungal colonization
Chen, Ying-Han, Yeung, Frank, Lacey, Keenan A, Zaldana, Kimberly, Lin, Jian-Da, Bee, Gavyn Chern Wei, McCauley, Caroline, Barre, Ramya S, Liang, Shen-Huan, Hansen, Christina B, Downie, Alexander E, Tio, Kyle, Weiser, Jeffrey N, Torres, Victor J, Bennett, Richard J, Loke, P'ng, Graham, Andrea L, Cadwell, Ken
Published in Science immunology (23.06.2023)
Published in Science immunology (23.06.2023)
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Dietary and water restriction leads to increased susceptibility to antimicrobial resistant pathogens
Lacey, Keenan A, Pickrum, Adam M, Gonzalez, Sandra, Bartnicki, Eric, Castellaw, Ashley H, Rodrick, Tori C, Jones, Drew R, Khanna, Kamal M, Torres, Victor J
Published in Science advances (26.07.2024)
Published in Science advances (26.07.2024)
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