Inhibitor of apoptosis proteins, NAIP, cIAP1 and cIAP2 expression during macrophage differentiation and M1/M2 polarization
Morón-Calvente, Virginia, Romero-Pinedo, Salvador, Toribio-Castelló, Sofía, Plaza-Díaz, Julio, Abadía-Molina, Ana C, Rojas-Barros, Domingo I, Beug, Shawn T, LaCasse, Eric C, MacKenzie, Alex, Korneluk, Robert, Abadía-Molina, Francisco
Published in PloS one (08.03.2018)
Published in PloS one (08.03.2018)
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Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma
Beug, Shawn T., Beauregard, Caroline E., Healy, Cristin, Sanda, Tarun, St-Jean, Martine, Chabot, Janelle, Walker, Danielle E., Mohan, Aditya, Earl, Nathalie, Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Staeheli, Peter, Forsyth, Peter A., Alain, Tommy, LaCasse, Eric C., Korneluk, Robert G.
Published in Nature communications (15.02.2017)
Published in Nature communications (15.02.2017)
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Modulation of immune signalling by inhibitors of apoptosis
Beug, Shawn T, Cheung, Herman H, LaCasse, Eric C, Korneluk, Robert G
Published in Trends in immunology (01.11.2012)
Published in Trends in immunology (01.11.2012)
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Smac mimetics and innate immune stimuli synergize to promote tumor death
Beug, Shawn T, Tang, Vera A, LaCasse, Eric C, Cheung, Herman H, Beauregard, Caroline E, Brun, Jan, Nuyens, Jeffrey P, Earl, Nathalie, St-Jean, Martine, Holbrook, Janelle, Dastidar, Himika, Mahoney, Douglas J, Ilkow, Carolina, Le Boeuf, Fabrice, Bell, John C, Korneluk, Robert G
Published in Nature biotechnology (01.02.2014)
Published in Nature biotechnology (01.02.2014)
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LCL161 enhances expansion and survival of engineered anti-tumor T cells but is restricted by death signaling
Afsahi, Arya, Silvestri, Christopher M, Moore, Allyson E, Graham, Carly F, Bacchiochi, Kaylyn, St-Jean, Martine, Baker, Christopher L, Korneluk, Robert G, Beug, Shawn T, LaCasse, Eric C, Bramson, Jonathan L
Published in Frontiers in immunology (17.04.2023)
Published in Frontiers in immunology (17.04.2023)
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Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy
Lala-Tabbert, Neena, Lejmi-Mrad, Rim, Timusk, Kristen, Fukano, Marina, Holbrook, Janelle, St-Jean, Martine, LaCasse, Eric C, Korneluk, Robert G
Published in Skeletal muscle (24.05.2019)
Published in Skeletal muscle (24.05.2019)
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Down-regulation of c-FLIP Enhances Death of Cancer Cells by Smac Mimetic Compound
CHEUNG, Herman H, MAHONEY, Douglas J, LACASSE, Eric C, KORNELUK, Robert G
Published in Cancer research (Chicago, Ill.) (01.10.2009)
Published in Cancer research (Chicago, Ill.) (01.10.2009)
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XIAP protection of photoreceptors in animal models of retinitis pigmentosa
Leonard, Kevin C, Petrin, Dino, Coupland, Stuart G, Baker, Adam N, Leonard, Brian C, LaCasse, Eric C, Hauswirth, William W, Korneluk, Robert G, Tsilfidis, Catherine
Published in PloS one (21.03.2007)
Published in PloS one (21.03.2007)
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The transcription factor SP3 drives TNF-α expression in response to Smac mimetics
Beug, Shawn T, Cheung, Herman H, Sanda, Tarun, St-Jean, Martine, Beauregard, Caroline E, Mamady, Hapsatou, Baird, Stephen D, LaCasse, Eric C, Korneluk, Robert G
Published in Science signaling (29.01.2019)
Published in Science signaling (29.01.2019)
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Antisense Oligonucleotides Targeting XIAP Induce Apoptosis and Enhance Chemotherapeutic Activity against Human Lung Cancer Cells in Vitro and in Vivo
Hu, YanPing, Cherton-Horvat, Gabriele, Dragowska, Visia, Baird, Stephen, Korneluk, Robert G, Durkin, Jon P, Mayer, Lawrence D, LaCasse, Eric C
Published in Clinical cancer research (01.07.2003)
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Published in Clinical cancer research (01.07.2003)
Journal Article
Preclinical Characterization of AEG35156/GEM 640, a Second-Generation Antisense Oligonucleotide Targeting X-Linked Inhibitor of Apoptosis
LACASSE, Eric C, CHERTON-HORVAT, Gabriele G, AGRAWAL, Sudhir, GILLARD, John W, DURKIN, Jon P, HEWITT, Kimberley E, JEROME, Lori J, MORRIS, Stephen J, KANDIMALLA, Ekambar R, DONG YU, HUI WANG, WEI WANG, RUIWEN ZHANG
Published in Clinical cancer research (01.09.2006)
Published in Clinical cancer research (01.09.2006)
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Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model
Dobson, Christine C, Naing, Thet, Beug, Shawn T, Faye, Mame D, Chabot, Janelle, St-Jean, Martin, Walker, Danielle E, LaCasse, Eric C, Stojdl, David F, Korneluk, Robert G, Holcik, Martin
Published in Oncotarget (10.01.2017)
Published in Oncotarget (10.01.2017)
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