Mechanisms of Acquired Resistance to Trastuzumab Emtansine in Breast Cancer Cells
Li, Guangmin, Guo, Jun, Shen, Ben-Quan, Yadav, Daniela Bumbaca, Sliwkowski, Mark X, Crocker, Lisa M, Lacap, Jennifer A, Phillips, Gail D Lewis
Published in Molecular cancer therapeutics (01.07.2018)
Published in Molecular cancer therapeutics (01.07.2018)
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Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling
Holden, Jeffrey K., Crawford, James J., Noland, Cameron L., Schmidt, Stephen, Zbieg, Jason R., Lacap, Jennifer A., Zang, Richard, Miller, Gregory M., Zhang, Yue, Beroza, Paul, Reja, Rohit, Lee, Wendy, Tom, Jeffrey Y.K., Fong, Rina, Steffek, Micah, Clausen, Saundra, Hagenbeek, Thjis J., Hu, Taishan, Zhou, Zheng, Shen, Hong C., Cunningham, Christian N.
Published in Cell reports (Cambridge) (23.06.2020)
Published in Cell reports (Cambridge) (23.06.2020)
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An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance
Hagenbeek, Thijs J, Zbieg, Jason R, Hafner, Marc, Mroue, Rana, Lacap, Jennifer A, Sodir, Nicole M, Noland, Cameron L, Afghani, Shervin, Kishore, Ayush, Bhat, Kamakoti P, Yao, Xiaosai, Schmidt, Stephen, Clausen, Saundra, Steffek, Micah, Lee, Wendy, Beroza, Paul, Martin, Scott, Lin, Eva, Fong, Rina, Di Lello, Paola, Kubala, Marta H, Yang, Michelle N-Y, Lau, Jeffrey T, Chan, Emily, Arrazate, Alfonso, An, Le, Levy, Elizabeth, Lorenzo, Maria N, Lee, Ho-June, Pham, Trang H, Modrusan, Zora, Zang, Richard, Chen, Yi-Chen, Kabza, Michal, Ahmed, Musaddeque, Li, Jason, Chang, Matthew T, Maddalo, Danilo, Evangelista, Marie, Ye, Xin, Crawford, James J, Dey, Anwesha
Published in Nature cancer (01.06.2023)
Published in Nature cancer (01.06.2023)
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MAPK pathway inhibition enhances the efficacy of an anti-endothelin B receptor drug conjugate by inducing target expression in melanoma
Asundi, Jyoti, Lacap, Jennifer A, Clark, Suzanna, Nannini, Michelle, Roth, Leslie, Polakis, Paul
Published in Molecular cancer therapeutics (01.06.2014)
Published in Molecular cancer therapeutics (01.06.2014)
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Supplementation of Nicotinic Acid with NAMPT Inhibitors Results in Loss of In Vivo Efficacy in NAPRT1 -Deficient Tumor Models
O'Brien, Thomas, Oeh, Jason, Xiao, Yang, Liang, Xiaorong, Vanderbilt, Alexander, Qin, Ann, Yang, Lulu, Lee, Leslie B, Ly, Justin, Cosino, Ely, LaCap, Jennifer A, Ogasawara, Annie, Williams, Simon, Nannini, Michelle, Liederer, Bianca M, Jackson, Peter, Dragovich, Peter S, Sampath, Deepak
Published in Neoplasia (New York, N.Y.) (01.12.2013)
Published in Neoplasia (New York, N.Y.) (01.12.2013)
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KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer
Burgess, Michael R., Hwang, Eugene, Mroue, Rana, Bielski, Craig M., Wandler, Anica M., Huang, Benjamin J., Firestone, Ari J., Young, Amy, Lacap, Jennifer A., Crocker, Lisa, Asthana, Saurabh, Davis, Elizabeth M., Xu, Jin, Akagi, Keiko, Le Beau, Michelle M., Li, Qing, Haley, Benjamin, Stokoe, David, Sampath, Deepak, Taylor, Barry S., Evangelista, Marie, Shannon, Kevin
Published in Cell (23.02.2017)
Published in Cell (23.02.2017)
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Machine-Learning and Chemicogenomics Approach Defines and Predicts Cross-Talk of Hippo and MAPK Pathways
Pham, Trang H, Hagenbeek, Thijs J, Lee, Ho-June, Li, Jason, Rose, Christopher M, Lin, Eva, Yu, Mamie, Martin, Scott E, Piskol, Robert, Lacap, Jennifer A, Sampath, Deepak, Pham, Victoria C, Modrusan, Zora, Lill, Jennie R, Klijn, Christiaan, Malek, Shiva, Chang, Matthew T, Dey, Anwesha
Published in Cancer discovery (01.03.2021)
Published in Cancer discovery (01.03.2021)
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Abstract 2924: MAPK pathway inhibition enhances the efficacy of an anti-endothelin B receptor drug conjugate by inducing target expression in melanoma
Asundi, Jyoti, Polakis, Paul, Lacap, Jennifer A., Nannini, Michelle
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Differential Effects of Predosing on Tumor and Tissue Uptake of an 111 In-Labeled Anti-TENB2 Antibody–Drug Conjugate
Boswell, C. Andrew, Mundo, Eduardo E., Zhang, Crystal, Stainton, Shannon L., Yu, Shang-Fan, Lacap, Jennifer A., Mao, Weiguang, Kozak, Katherine R., Fourie, Aimee, Polakis, Paul, Khawli, Leslie A., Lin, Kedan
Published in Journal of Nuclear Medicine (01.09.2012)
Published in Journal of Nuclear Medicine (01.09.2012)
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Supplementation of Nicotinic Acid with NAMPT Inhibitors Results in Loss of In Vivo Efficacy in NAPRT1-Deficient Tumor Models1
O'Brien, Thomas, Oeh, Jason, Xiao, Yang, Liang, Xiaorong, Vanderbilt, Alexander, Qin, Ann, Yang, Lulu, Lee, Leslie B, Ly, Justin, Cosino, Ely, LaCap, Jennifer A, Ogasawara, Annie, Williams, Simon, Nannini, Michelle, Liederer, Bianca M, Jackson, Peter, Dragovich, Peter S, Sampath, Deepak
Published in Neoplasia (New York, N.Y.) (01.12.2013)
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Published in Neoplasia (New York, N.Y.) (01.12.2013)
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Differential Effects of Predosing on Tumor and Tissue Uptake of an ^sup 111^In-Labeled Anti-TENB2 Antibody-Drug Conjugate
Boswell, C Andrew, Mundo, Eduardo E, Zhang, Crystal, Stainton, Shannon L, Yu, Shang-Fan, Lacap, Jennifer A, Mao, Weiguang, Kozak, Katherine R, Fourie, Aimee, Polakis, Paul, Khawli, Leslie A, Lin, Kedan
Published in The Journal of nuclear medicine (1978) (01.09.2012)
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Published in The Journal of nuclear medicine (1978) (01.09.2012)
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Differential effects of predosing on tumor and tissue uptake of an 111In-labeled anti-TENB2 antibody-drug conjugate
Boswell, C Andrew, Mundo, Eduardo E, Zhang, Crystal, Stainton, Shannon L, Yu, Shang-Fan, Lacap, Jennifer A, Mao, Weiguang, Kozak, Katherine R, Fourie, Aimee, Polakis, Paul, Khawli, Leslie A, Lin, Kedan
Published in The Journal of nuclear medicine (1978) (01.09.2012)
Published in The Journal of nuclear medicine (1978) (01.09.2012)
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