A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target
Srivastava, Prashant K., van Eyll, Jonathan, Godard, Patrice, Mazzuferi, Manuela, Delahaye-Duriez, Andree, Van Steenwinckel, Juliette, Gressens, Pierre, Danis, Benedicte, Vandenplas, Catherine, Foerch, Patrik, Leclercq, Karine, Mairet-Coello, Georges, Cardenas, Alvaro, Vanclef, Frederic, Laaniste, Liisi, Niespodziany, Isabelle, Keaney, James, Gasser, Julien, Gillet, Gaelle, Shkura, Kirill, Chong, Seon-Ah, Behmoaras, Jacques, Kadiu, Irena, Petretto, Enrico, Kaminski, Rafal M., Johnson, Michael R.
Published in Nature communications (03.09.2018)
Published in Nature communications (03.09.2018)
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Integrated systems‐genetic analyses reveal a network target for delaying glioma progression
Laaniste, Liisi, Srivastava, Prashant K., Stylianou, Julianna, Syed, Nelofer, Cases‐Cunillera, Silvia, Shkura, Kirill, Zeng, Qingyu, Rackham, Owen J. L., Langley, Sarah R., Delahaye-Duriez, Andree, O'Neill, Kevin, Williams, Matthew, Becker, Albert, Roncaroli, Federico, Petretto, Enrico, Johnson, Michael R.
Published in Annals of clinical and translational neurology (01.09.2019)
Published in Annals of clinical and translational neurology (01.09.2019)
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Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery
Delahaye-Duriez, Andree, Srivastava, Prashant, Shkura, Kirill, Langley, Sarah R, Laaniste, Liisi, Moreno-Moral, Aida, Danis, Bénédicte, Mazzuferi, Manuela, Foerch, Patrik, Gazina, Elena V, Richards, Kay, Petrou, Steven, Kaminski, Rafal M, Petretto, Enrico, Johnson, Michael R
Published in Genome Biology (13.12.2016)
Published in Genome Biology (13.12.2016)
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Alterations of bronchial epithelial metabolome by cigarette smoke are reversible by an antioxidant, O-methyl-L-tyrosinyl-γ-L-glutamyl-L-cysteinylglycine
Aug, Argo, Altraja, Alan, Altraja, Siiri, Laaniste, Liisi, Mahlapuu, Riina, Soomets, Ursel, Kilk, Kalle
Published in American journal of respiratory cell and molecular biology (01.10.2014)
Published in American journal of respiratory cell and molecular biology (01.10.2014)
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Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas
Zhang, Lei, Kundu, Soumi, Feenstra, Tjerk, Li, Xiujuan, Jin, Chuan, Laaniste, Liisi, El Hassan, Tamador Elsir Abu, Ohlin, K Elisabet, Yu, Di, Olofsson, Tommie, Olsson, Anna-Karin, Pontén, Fredrik, Magnusson, Peetra U, Nilsson, Karin Forsberg, Essand, Magnus, Smits, Anja, Dieterich, Lothar C, Dimberg, Anna
Published in Science signaling (08.12.2015)
Published in Science signaling (08.12.2015)
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Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells
Zhang, Lei, Laaniste, Liisi, Jiang, Yiwen, Alafuzoff, Irina, Uhrbom, Lene, Dimberg, Anna
Published in Oncotarget (06.12.2016)
Published in Oncotarget (06.12.2016)
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L. Laaniste et al
Laaniste, Liisi, Srivastava, Prashant K, Stylianou, Julianna, Nelofer Syed, Silvia Cases‐Cunillera, Shkura, Kirill, Zeng, Qingyu, Rackham, Owen J L, Langley, Sarah R, Delahaye-Duriez, Andree, O'Neill, Kevin, Williams, Matthew, Becker, Albert, Roncaroli, Federico, Petretto, Enrico, Johnson, Michael R
Published in Annals of clinical and translational neurology (01.09.2019)
Published in Annals of clinical and translational neurology (01.09.2019)
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Alterations of Bronchial Epithelial Metabolome by Cigarette Smoke Are Reversible by an Antioxidant, O-Methyl-L-Tyrosinyl-[gamma]-L-Glutamyl-L-Cysteinylglycine
Aug, Argo, Altraja, Alan, Altraja, Siiri, Laaniste, Liisi, Mahlapuu, Riina, Soomets, Ursel, Kilk, Kalle
Published in American journal of respiratory cell and molecular biology (01.10.2014)
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Published in American journal of respiratory cell and molecular biology (01.10.2014)
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Single-cell Mendelian randomisation identifies cell-type specific genetic effects on human brain disease and behaviour
Haglund, Alexander, Zuber, Verena, Yang, Yifei, Abouzeid, Maya, Feleke, Rahel, Jeong-Hun Ko, Nott, Alexi, Babtie, Ann C, Mills, James D, Louwai Muhammed, Laaniste, Liisi, Gveric, Djordje O, Clode, Daniel, Pagni, Susanna, Ravishankara Bellampalli, Somani, Alyma, Mcdade, Karina, Anink, Jasper J, Mesarosova, Lucia, Aronica, Eleonora, Thom, Maria, Sisodiya, Sanjay M, Srivastava, Prashant K, Malhotra, Dheeraj, Bryois, Julien, Bottolo, Leonardo, Johnson, Michael R
Published in bioRxiv (29.11.2022)
Published in bioRxiv (29.11.2022)
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A Systems-Level Framework For Drug Discovery Identifies Csf1R As A Novel Anti-Epileptic Drug Target
Srivastava, Prashant K, Jonathan Van Eyll, Godard, Patrice, Mazzuferi, Manuela, Danis, Benedicte, Vandenplas, Catherine, Foerch, Patrik, Leclercq, Karine, Mairet-Coello, Georges, Vanclef, Frederic, Shkura, Kirill, Laaniste, Liisi, Delahaye-Duriez, Andree, Kaminski, Rafal M, Petretto, Enrico, Johnson, Michael R
Published in bioRxiv (22.05.2017)
Published in bioRxiv (22.05.2017)
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