Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: Implications for chemotherapy-induced peripheral neuropathy
LaPointe, Nichole E., Morfini, Gerardo, Brady, Scott T., Feinstein, Stuart C., Wilson, Leslie, Jordan, Mary Ann
Published in Neurotoxicology (Park Forest South) (01.07.2013)
Published in Neurotoxicology (Park Forest South) (01.07.2013)
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Journal Article
Tau Assembly: The Dominant Role of PHF6 (VQIVYK) in Microtubule Binding Region Repeat R3
Ganguly, Pritam, Do, Thanh D, Larini, Luca, LaPointe, Nichole E, Sercel, Alexander J, Shade, Madeleine F, Feinstein, Stuart C, Bowers, Michael T, Shea, Joan-Emma
Published in The journal of physical chemistry. B (02.04.2015)
Published in The journal of physical chemistry. B (02.04.2015)
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Journal Article
The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity
LaPointe, Nichole E., Morfini, Gerardo, Pigino, Gustavo, Gaisina, Irina N., Kozikowski, Alan P., Binder, Lester I., Brady, Scott T.
Published in Journal of neuroscience research (01.02.2009)
Published in Journal of neuroscience research (01.02.2009)
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Journal Article
Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport
Kanaan, Nicholas M, Morfini, Gerardo, Pigino, Gustavo, LaPointe, Nichole E, Andreadis, Athena, Song, Yuyu, Leitman, Ellen, Binder, Lester I, Brady, Scott T
Published in Neurobiology of aging (01.04.2012)
Published in Neurobiology of aging (01.04.2012)
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Journal Article
Oligomerization of the microtubule‐associated protein tau is mediated by its N‐terminal sequences: implications for normal and pathological tau action
Feinstein, H. Eric, Benbow, Sarah J., LaPointe, Nichole E., Patel, Nirav, Ramachandran, Srinivasan, Do, Thanh D., Gaylord, Michelle R., Huskey, Noelle E., Dressler, Nicolette, Korff, Megan, Quon, Brady, Cantrell, Kristi Lazar, Bowers, Michael T., Lal, Ratnesh, Feinstein, Stuart C.
Published in Journal of neurochemistry (01.06.2016)
Published in Journal of neurochemistry (01.06.2016)
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Journal Article
A novel MAPT mutation, G55R, in a frontotemporal dementia patient leads to altered Tau function
Iyer, Abhinaya, Lapointe, Nichole E, Zielke, Krzysztof, Berdynski, Mariusz, Guzman, Elmer, Barczak, Anna, Chodakowska-Żebrowska, Małgorzata, Barcikowska, Maria, Feinstein, Stuart, Zekanowski, Cezary
Published in PloS one (27.09.2013)
Published in PloS one (27.09.2013)
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Journal Article
Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy
Best, Rebecca L., LaPointe, Nichole E., Azarenko, Olga, Miller, Herb, Genualdi, Christine, Chih, Stephen, Shen, Ben-Quan, Jordan, Mary Ann, Wilson, Leslie, Feinstein, Stuart C., Stagg, Nicola J.
Published in Toxicology and applied pharmacology (15.06.2021)
Published in Toxicology and applied pharmacology (15.06.2021)
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Journal Article
Amyloid β‑Protein C‑Terminal Fragments: Formation of Cylindrins and β‑Barrels
Do, Thanh D, LaPointe, Nichole E, Nelson, Rebecca, Krotee, Pascal, Hayden, Eric Y, Ulrich, Brittany, Quan, Sarah, Feinstein, Stuart C, Teplow, David B, Eisenberg, David, Shea, Joan-Emma, Bowers, Michael T
Published in Journal of the American Chemical Society (20.01.2016)
Published in Journal of the American Chemical Society (20.01.2016)
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Journal Article
Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases
Kanaan, Nicholas M, Morfini, Gerardo A, LaPointe, Nichole E, Pigino, Gustavo F, Patterson, Kristina R, Song, Yuyu, Andreadis, Athena, Fu, Yifan, Brady, Scott T, Binder, Lester I
Published in The Journal of neuroscience (06.07.2011)
Published in The Journal of neuroscience (06.07.2011)
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Journal Article
Tau isoform–specific stabilization of intermediate states during microtubule assembly and disassembly
Best, Rebecca L., LaPointe, Nichole E., Liang, Jiahao, Ruan, Kevin, Shade, Madeleine F., Wilson, Leslie, Feinstein, Stuart C.
Published in The Journal of biological chemistry (16.08.2019)
Published in The Journal of biological chemistry (16.08.2019)
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Journal Article
Tau Aggregation Propensity Engrained in Its Solution State
Eschmann, Neil A, Do, Thanh D, LaPointe, Nichole E, Shea, Joan-Emma, Feinstein, Stuart C, Bowers, Michael T, Han, Songi
Published in The journal of physical chemistry. B (12.11.2015)
Published in The journal of physical chemistry. B (12.11.2015)
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Journal Article
Initiation of assembly of tau(273-284) and its ΔK280 mutant: an experimental and computational study
Larini, Luca, Gessel, Megan Murray, LaPointe, Nichole E, Do, Thanh D, Bowers, Michael T, Feinstein, Stuart C, Shea, Joan-Emma
Published in Physical chemistry chemical physics : PCCP (21.06.2013)
Published in Physical chemistry chemical physics : PCCP (21.06.2013)
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Journal Article
Cinnamon Extract Inhibits Tau Aggregation Associated with Alzheimer's Disease In Vitro
Peterson, Dylan W., George, Roshni C., Scaramozzino, Francesca, LaPointe, Nichole E., Anderson, Richard A., Graves, Donald J., Lew, John
Published in Journal of Alzheimer's disease (2009)
Published in Journal of Alzheimer's disease (2009)
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Journal Article
1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose binds to the N-terminal metal binding region to inhibit amyloid β-protein oligomer and fibril formation
de Almeida, Natália E.C., Do, Thanh D., LaPointe, Nichole E., Tro, Michael, Feinstein, Stuart C., Shea, Joan-Emma, Bowers, Michael T.
Published in International journal of mass spectrometry (01.09.2017)
Published in International journal of mass spectrometry (01.09.2017)
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Journal Article