Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance
Lukens, Amanda K., Ross, Leila Saxby, Heidebrecht, Richard, Gamo, Francisco Javier, Lafuente-Monasterio, Maria J., Booker, Michael L., Hartl, Daniel L., Wiegand, Roger C., Wirth, Dyann F.
Published in Proceedings of the National Academy of Sciences - PNAS (14.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (14.01.2014)
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Case Study of Small Molecules As Antimalarials: 2‑Amino-1-phenylethanol (APE) Derivatives
Chaparro, María J, Vidal, Jaume, Angulo-Barturen, Íñigo, Bueno, José M, Burrows, Jeremy, Cammack, Nicholas, Castañeda, Pablo, Colmenarejo, Gonzalo, Coterón, José M, de las Heras, Laura, Fernández, Esther, Ferrer, Santiago, Gabarró, Raquel, Gamo, Francisco J, García, Mercedes, Jiménez-Díaz, María B, Lafuente, María J, León, María L, Martínez, María S, Minick, Douglas, Prats, Sara, Puente, Margarita, Rueda, Lourdes, Sandoval, Elena, Santos-Villarejo, Ángel, Witty, Michael, Calderón, Félix
Published in ACS medicinal chemistry letters (12.06.2014)
Published in ACS medicinal chemistry letters (12.06.2014)
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New insights into host-parasite ubiquitin proteome dynamics in P. falciparum infected red blood cells using a TUBEs-MS approach
Mata-Cantero, Lydia, Azkargorta, Mikel, Aillet, Fabienne, Xolalpa, Wendy, LaFuente, Maria J., Elortza, Felix, Carvalho, Ana Sofia, Martin-Plaza, Julio, Matthiesen, Rune, Rodriguez, Manuel S.
Published in Journal of proteomics (29.04.2016)
Published in Journal of proteomics (29.04.2016)
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Journal Article
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages
Arendse, Lauren B, Murithi, James M, Qahash, Tarrick, Pasaje, Charisse Flerida A, Godoy, Luiz C, Dey, Sumanta, Gibhard, Liezl, Ghidelli-Disse, Sonja, Drewes, Gerard, Bantscheff, Marcus, Lafuente-Monasterio, Maria J, Fienberg, Stephen, Wambua, Lynn, Gachuhi, Samuel, Coertzen, Dina, van der Watt, Mariëtte, Reader, Janette, Aswat, Ayesha S, Erlank, Erica, Venter, Nelius, Mittal, Nimisha, Luth, Madeline R, Ottilie, Sabine, Winzeler, Elizabeth A, Koekemoer, Lizette L, Birkholtz, Lyn-Marie, Niles, Jacquin C, Llinás, Manuel, Fidock, David A, Chibale, Kelly
Published in Science translational medicine (19.10.2022)
Published in Science translational medicine (19.10.2022)
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Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug
da Cruz, Filipa P., Martin, Cécilie, Buchholz, Kathrin, Lafuente-Monasterio, Maria J., Rodrigues, Tiago, Sönnichsen, Birte, Moreira, Rui, Gamo, Francisco-Javier, Marti, Matthias, Mota, Maria M., Hannus, Michael, Prudêncio, Miguel
Published in The Journal of infectious diseases (15.04.2012)
Published in The Journal of infectious diseases (15.04.2012)
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Journal Article
Quinolin-4(1H)‑imines are Potent Antiplasmodial Drugs Targeting the Liver Stage of Malaria
Rodrigues, Tiago, da Cruz, Filipa P, Lafuente-Monasterio, Maria J, Gonçalves, Daniel, Ressurreição, Ana S, Sitoe, Ana R, Bronze, Maria R, Gut, Jiri, Schneider, Gisbert, Mota, Maria M, Rosenthal, Philip J, Prudêncio, Miguel, Gamo, Francisco-Javier, Lopes, Francisca, Moreira, Rui
Published in Journal of medicinal chemistry (13.06.2013)
Published in Journal of medicinal chemistry (13.06.2013)
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Journal Article
Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors
Dong, Carolyn K, Urgaonkar, Sameer, Cortese, Joseph F, Gamo, Francisco-Javier, Garcia-Bustos, Jose F, Lafuente, Maria J, Patel, Vishal, Ross, Leila, Coleman, Bradley I, Derbyshire, Emily R, Clish, Clary B, Serrano, Adelfa E, Cromwell, Mandy, Barker, Jr, Robert H, Dvorin, Jeffrey D, Duraisingh, Manoj T, Wirth, Dyann F, Clardy, Jon, Mazitschek, Ralph
Published in Chemistry & biology (23.12.2011)
Published in Chemistry & biology (23.12.2011)
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Journal Article
Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc 1 Inhibitors
Dong, Carolyn K., Urgaonkar, Sameer, Cortese, Joseph F., Gamo, Francisco-Javier, Garcia-Bustos, Jose F., Lafuente, Maria J., Patel, Vishal, Ross, Leila, Coleman, Bradley I., Derbyshire, Emily R., Clish, Clary B., Serrano, Adelfa E., Cromwell, Mandy, Barker, Robert H., Dvorin, Jeffrey D., Duraisingh, Manoj T., Wirth, Dyann F., Clardy, Jon, Mazitschek, Ralph
Published in Chemistry & biology (23.12.2011)
Published in Chemistry & biology (23.12.2011)
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Journal Article
Analysis of the DNA sequence of a 15,500 bp fragment near the left telomere of chromosome XV from Saccharomyces cerevisiae reveals a putative sugar transporter, a carboxypeptidase homologue and two new open reading frames
Gamo, Francisco‐Javier, Lafuente, María J, Casamayor, Antonio, Ariño, Joaquín, Aldea, Martí, Casas, Celia, Herrero, Enrique, Gancedo, Carlos
Published in Yeast (Chichester, England) (15.06.1996)
Published in Yeast (Chichester, England) (15.06.1996)
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DNA sequence analysis of a 10 624 bp fragment of the left arm of chromosome XV fromSaccharomyces cerevisiae reveals a RNA binding protein, a mitochondrial protein, two ribosomal proteins and two new open reading frames
Lafuente, María J., Gamo, Francisco-Javier, Gancedo, Carlos
Published in Yeast (Chichester, England) (01.09.1996)
Published in Yeast (Chichester, England) (01.09.1996)
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Journal Article
DNA sequence analysis of a 10 624 bp fragment of the left arm of chromosome XV from Saccharomyces cerevisiae reveals a RNA binding protein, a mitochondrial protein, two ribosomal proteins and two new open reading frames
Lafuente, María J., Gamo, Francisco‐Javier, Gancedo, Carlos
Published in Yeast (Chichester, England) (01.09.1996)
Published in Yeast (Chichester, England) (01.09.1996)
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