An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs
Chapple, Richard H, Liu, Xueying, Natarajan, Sivaraman, Alexander, Margaret I M, Kim, Yuna, Patel, Anand G, LaFlamme, Christy W, Pan, Min, Wright, William C, Lee, Hyeong-Min, Zhang, Yinwen, Lu, Meifen, Koo, Selene C, Long, Courtney, Harper, John, Savage, Chandra, Johnson, Melissa D, Confer, Thomas, Akers, Walter J, Dyer, Michael A, Sheppard, Heather, Easton, John, Geeleher, Paul
Published in Genome Biology (19.06.2024)
Published in Genome Biology (19.06.2024)
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Leveraging multiple approaches for the detection of pathogenic deep intronic variants in developmental and epileptic encephalopathies: A case report
Nyaga, Denis M., Hildebrand, Michael S., Valles‐Ibáñez, Guillem, Keenan, Ngaire F., Ye, Zimeng, LaFlamme, Christy W., Mefford, Heather C., Bennett, Mark F., Bahlo, Melanie, Sadleir, Lynette G.
Published in Epilepsia open (01.04.2024)
Published in Epilepsia open (01.04.2024)
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Diagnostic utility of DNA methylation analysis in genetically unsolved pediatric epilepsies and CHD2 episignature refinement
LaFlamme, Christy W., Rastin, Cassandra, Sengupta, Soham, Pennington, Helen E., Russ-Hall, Sophie J., Schneider, Amy L., Bonkowski, Emily S., Almanza Fuerte, Edith P., Allan, Talia J., Zalusky, Miranda Perez-Galey, Goffena, Joy, Gibson, Sophia B., Nyaga, Denis M., Lieffering, Nico, Hebbar, Malavika, Walker, Emily V., Darnell, Daniel, Olsen, Scott R., Kolekar, Pandurang, Djekidel, Mohamed Nadhir, Rosikiewicz, Wojciech, McConkey, Haley, Kerkhof, Jennifer, Levy, Michael A., Relator, Raissa, Lev, Dorit, Lerman-Sagie, Tally, Park, Kristen L., Alders, Marielle, Cappuccio, Gerarda, Chatron, Nicolas, Demain, Leigh, Genevieve, David, Lesca, Gaetan, Roscioli, Tony, Sanlaville, Damien, Tedder, Matthew L., Gupta, Sachin, Jones, Elizabeth A., Weisz-Hubshman, Monika, Ketkar, Shamika, Dai, Hongzheng, Worley, Kim C., Rosenfeld, Jill A., Chao, Hsiao-Tuan, Neale, Geoffrey, Carvill, Gemma L., Wang, Zhaoming, Berkovic, Samuel F., Sadleir, Lynette G., Miller, Danny E., Scheffer, Ingrid E., Sadikovic, Bekim, Mefford, Heather C.
Published in Nature communications (06.08.2024)
Published in Nature communications (06.08.2024)
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An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs
Chapple, Richard H, Liu, Xueying, Natarajan, Sivaraman, Alexander, Margaret I M, Kim, Yuna, Patel, Anand G, LaFlamme, Christy W, Pan, Min, Wright, William C, Lee, Hyeong-Min, Zhang, Yinwen, Lu, Meifen, Koo, Selene C, Long, Courtney, Harper, John, Savage, Chandra, Johnson, Melissa D, Confer, Thomas, Akers, Walter J, Dyer, Michael A, Sheppard, Heather, Easton, John, Geeleher, Paul
Published in bioRxiv (22.04.2024)
Published in bioRxiv (22.04.2024)
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Diagnostic Utility of Genome-wide DNA Methylation Analysis in Genetically Unsolved Developmental and Epileptic Encephalopathies and Refinement of a CHD2 Episignature
LaFlamme, Christy W, Rastin, Cassandra, Sengupta, Soham, Pennington, Helen E, Russ-Hall, Sophie J, Schneider, Amy L, Bonkowski, Emily S, Almanza Fuerte, Edith P, Galey, Miranda, Goffena, Joy, Gibson, Sophia B, Allan, Talia J, Nyaga, Denis M, Lieffering, Nico, Hebbar, Malavika, Walker, Emily V, Darnell, Daniel, Olsen, Scott R, Kolekar, Pandurang, Djekidel, Nahdir, Rosikiewicz, Wojciech, McConkey, Haley, Kerkhof, Jennifer, Levy, Michael A, Relator, Raissa, Lev, Dorit, Lerman-Sagie, Tally, Park, Kristen L, Alders, Marielle, Cappuccio, Gerarda, Chatron, Nicolas, Demain, Leigh, Genevieve, David, Lesca, Gaetan, Roscioli, Tony, Sanlaville, Damien, Tedder, Matthew L, Hubshman, Monika Weisz, Ketkar, Shamika, Dai, Hongzheng, Worley, Kim Carlyle, Rosenfeld, Jill A, Chao, Hsiao-Tuan, Neale, Geoffrey, Carvill, Gemma L, Wang, Zhaoming, Berkovic, Samuel F, Sadleir, Lynette G, Miller, Danny E, Scheffer, Ingrid E, Sadikovic, Bekim, Mefford, Heather C
Published in medRxiv : the preprint server for health sciences (12.10.2023)
Published in medRxiv : the preprint server for health sciences (12.10.2023)
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Abstract B006: An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs
Chapple, Richard H., Liu, Xueying, Natarajan, Sivaraman, Alexander, Margaret I.M., Kim, Yuna, Patel, Anand G., LaFlamme, Christy W., Pan, Min, Wright, William C., Lee, Hyeong-Min, Zhang, Yinwen, Lu, Meifen, Koo, Selene C., Long, Courtney, Harper, John, Savage, Chandra, Johnson, Melissa D., Confer, Thomas, Akers, Walter J., Dyer, Michael A., Sheppard, Heather, Easton, John, Geeleher, Paul
Published in Cancer research (Chicago, Ill.) (05.09.2024)
Published in Cancer research (Chicago, Ill.) (05.09.2024)
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Abstract 868: A novel unsupervised machine learning model applied to neuroblastoma single-cell RNA-seq data reveals a drug-induced mesenchymal-like gene expression program
Chapple, Rich, Liu, Xueying, Natarajan, Sivaraman, Alexander, Margaret I., Kim, Yuna, Patel, Anand, LaFlamme, Christy W., Pan, Min, Wright, William C., Lee, Hyeong-Min, Zhang, Yinwen, Lu, Meifen, Koo, Selene C., Long, Courtney, Harper, John, Savage, Chandra, Johnson, Melissa D., Confer, Thomas, Akers, Walter J., Dyer, Michael A., Sheppard, Heather, Easton, John, Geeleher, Paul
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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