Augmentation of Creatine in the Heart
Zervou, Sevasti, Whittington, Hannah J, Russell, Angela J, Lygate, Craig A
Published in Mini reviews in medicinal chemistry (01.01.2016)
Published in Mini reviews in medicinal chemistry (01.01.2016)
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Acute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans
Ruparelia, Neil, Godec, Jernej, Lee, Regent, Chai, Joshua T, Dall'Armellina, Erica, McAndrew, Debra, Digby, Janet E, Forfar, J Colin, Prendergast, Bernard D, Kharbanda, Rajesh K, Banning, Adrian P, Neubauer, Stefan, Lygate, Craig A, Channon, Keith M, Haining, Nicholas W, Choudhury, Robin P
Published in European heart journal (01.08.2015)
Published in European heart journal (01.08.2015)
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A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy
Ashrafian, Houman, Docherty, Louise, Leo, Vincenzo, Towlson, Christopher, Neilan, Monica, Steeples, Violetta, Lygate, Craig A, Hough, Tertius, Townsend, Stuart, Williams, Debbie, Wells, Sara, Norris, Dominic, Glyn-Jones, Sarah, Land, John, Barbaric, Ivana, Lalanne, Zuzanne, Denny, Paul, Szumska, Dorota, Bhattacharya, Shoumo, Griffin, Julian L, Hargreaves, Iain, Fernandez-Fuentes, Narcis, Cheeseman, Michael, Watkins, Hugh, Dear, T Neil
Published in PLoS genetics (24.06.2010)
Published in PLoS genetics (24.06.2010)
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Increasing creatine kinase activity protects against hypoxia / reoxygenation injury but not against anthracycline toxicity in vitro
Zervou, Sevasti, Whittington, Hannah J, Ostrowski, Philip J, Cao, Fang, Tyler, Jack, Lake, Hannah A, Neubauer, Stefan, Lygate, Craig A
Published in PloS one (14.08.2017)
Published in PloS one (14.08.2017)
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Synergistic effect on cardiac energetics by targeting the creatine kinase system: in vivo application of high-resolution 31P-CMRS in the mouse
Maguire, Mahon L., McAndrew, Debra J., Lake, Hannah A., Ostrowski, Philip J., Zervou, Sevasti, Neubauer, Stefan, Lygate, Craig A., Schneider, Jurgen E.
Published in Journal of cardiovascular magnetic resonance (06.02.2023)
Published in Journal of cardiovascular magnetic resonance (06.02.2023)
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A Mouse Model of Creatine Transporter Deficiency Reveals Impaired Motor Function and Muscle Energy Metabolism
Stockebrand, Malte, Sasani, Ali, Das, Devashish, Hornig, Sönke, Hermans-Borgmeyer, Irm, Lake, Hannah A, Isbrandt, Dirk, Lygate, Craig A, Heerschap, Arend, Neu, Axel, Choe, Chi-Un
Published in Frontiers in physiology (22.06.2018)
Published in Frontiers in physiology (22.06.2018)
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Refined approach for quantification of in vivo ischemia-reperfusion injury in the mouse heart
Bohl, Steffen, Medway, Debra J, Schulz-Menger, Jeanette, Schneider, Jurgen E, Neubauer, Stefan, Lygate, Craig A
Published in American journal of physiology. Heart and circulatory physiology (01.12.2009)
Published in American journal of physiology. Heart and circulatory physiology (01.12.2009)
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Age-Dependent Decline in Cardiac Function in Guanidinoacetate- N -Methyltransferase Knockout Mice
Aksentijević, Dunja, Zervou, Sevasti, Eykyn, Thomas R, McAndrew, Debra J, Wallis, Julie, Schneider, Jurgen E, Neubauer, Stefan, Lygate, Craig A
Published in Frontiers in physiology (21.01.2020)
Published in Frontiers in physiology (21.01.2020)
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Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction
LYGATE, Craig A, BOHL, Steffen, CLARKE, Kieran, WATKINS, Hugh, SCHNEIDER, Jürgen E, NEUBAUER, Stefan, TEN HOVE, Michiel, FALLER, Kiterie M. E, OSTROWSKI, Philip J, ZERVOU, Sevasti, MEDWAY, Debra J, AKSENTIJEVIC, Dunja, SEBAG-MONTEFIORE, Liam, WALLIS, Julie
Published in Cardiovascular research (01.12.2012)
Published in Cardiovascular research (01.12.2012)
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Myocardial infarction causes inflammation and leukocyte recruitment at remote sites in the myocardium and in the renal glomerulus
Ruparelia, Neil, Digby, Janet E., Jefferson, Andrew, Medway, Debra J., Neubauer, Stefan, Lygate, Craig A., Choudhury, Robin P.
Published in Inflammation research (01.05.2013)
Published in Inflammation research (01.05.2013)
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Unchanged mitochondrial organization and compartmentation of high-energy phosphates in creatine-deficient GAMT-/- mouse hearts
Branovets, Jelena, Sepp, Mervi, Kotlyarova, Svetlana, Jepihhina, Natalja, Sokolova, Niina, Aksentijevic, Dunja, Lygate, Craig A, Neubauer, Stefan, Vendelin, Marko, Birkedal, Rikke
Published in American journal of physiology. Heart and circulatory physiology (15.08.2013)
Published in American journal of physiology. Heart and circulatory physiology (15.08.2013)
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Influence of homoarginine on creatine accumulation and biosynthesis in the mouse
Lygate, Craig A, Lake, Hannah A, McAndrew, Debra J, Neubauer, Stefan, Zervou, Sevasti
Published in Frontiers in nutrition (Lausanne) (09.08.2022)
Published in Frontiers in nutrition (Lausanne) (09.08.2022)
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Subtle Role for Adenylate Kinase 1 in Maintaining Normal Basal Contractile Function and Metabolism in the Murine Heart
Zervou, Sevasti, McAndrew, Debra J, Whittington, Hannah J, Lake, Hannah A, Park, Kyung Chan, Cha, Kuan Minn, Ostrowski, Philip J, Eykyn, Thomas R, Schneider, Jürgen E, Neubauer, Stefan, Lygate, Craig A
Published in Frontiers in physiology (31.03.2021)
Published in Frontiers in physiology (31.03.2021)
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Protective Effect of Creatine Elevation against Ischaemia Reperfusion Injury Is Retained in the Presence of Co-Morbidities and during Cardioplegia
Whittington, Hannah J, McAndrew, Debra J, Cross, Rebecca L, Neubauer, Stefan, Lygate, Craig A
Published in PloS one (14.01.2016)
Published in PloS one (14.01.2016)
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Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart
Murray, Andrew J, Cole, Mark A, Lygate, Craig A, Carr, Carolyn A, Stuckey, Daniel J, Little, Sarah E, Neubauer, Stefan, Clarke, Kieran
Published in Journal of molecular and cellular cardiology (01.04.2008)
Published in Journal of molecular and cellular cardiology (01.04.2008)
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Myocardial creatine levels do not influence response to acute oxidative stress in isolated perfused heart
Aksentijević, Dunja, Zervou, Sevasti, Faller, Kiterie M E, McAndrew, Debra J, Schneider, Jurgen E, Neubauer, Stefan, Lygate, Craig A
Published in PloS one (01.10.2014)
Published in PloS one (01.10.2014)
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