Immunotherapy for cardiovascular disease
Lutgens, Esther, Atzler, Dorothee, Döring, Yvonne, Duchene, Johan, Steffens, Sabine, Weber, Christian
Published in European heart journal (21.12.2019)
Published in European heart journal (21.12.2019)
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Immune cell crosstalk in obesity: a key role for costimulation?
Seijkens, Tom, Kusters, Pascal, Chatzigeorgiou, Antonios, Chavakis, Triantafyllos, Lutgens, Esther
Published in Diabetes (New York, N.Y.) (01.12.2014)
Published in Diabetes (New York, N.Y.) (01.12.2014)
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Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics
Depuydt, Marie A.C., Prange, Koen H.M., Slenders, Lotte, Örd, Tiit, Elbersen, Danny, Boltjes, Arjan, de Jager, Saskia C.A., Asselbergs, Folkert W., de Borst, Gert J., Aavik, Einari, Lönnberg, Tapio, Lutgens, Esther, Glass, Christopher K., den Ruijter, Hester M., Kaikkonen, Minna U., Bot, Ilze, Slütter, Bram, van der Laan, Sander W., Yla-Herttuala, Seppo, Mokry, Michal, Kuiper, Johan, de Winther, Menno P.J., Pasterkamp, Gerard
Published in Circulation research (06.11.2020)
Published in Circulation research (06.11.2020)
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Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death
Silvestre-Roig, Carlos, Braster, Quinte, Wichapong, Kanin, Lee, Ernest Y., Teulon, Jean Marie, Berrebeh, Nihel, Winter, Janine, Adrover, José M., Santos, Giancarlo Santiago, Froese, Alexander, Lemnitzer, Patricia, Ortega-Gómez, Almudena, Chevre, Raphael, Marschner, Julian, Schumski, Ariane, Winter, Carla, Perez-Olivares, Laura, Pan, Chang, Paulin, Nicole, Schoufour, Tom, Hartwig, Helene, González-Ramos, Silvia, Kamp, Frits, Megens, Remco T. A., Mowen, Kerri A., Gunzer, Matthias, Maegdefessel, Lars, Hackeng, Tilman, Lutgens, Esther, Daemen, Mat, von Blume, Julia, Anders, Hans-Joachim, Nikolaev, Viacheslav O., Pellequer, Jean-Luc, Weber, Christian, Hidalgo, Andrés, Nicolaes, Gerry A. F., Wong, Gerard C. L., Soehnlein, Oliver
Published in Nature (London) (01.05.2019)
Published in Nature (London) (01.05.2019)
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Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection
Zernecke, Alma, Bidzhekov, Kiril, Noels, Heidi, Shagdarsuren, Erdenechimeg, Gan, Lin, Denecke, Bernd, Hristov, Mihail, Köppel, Thomas, Jahantigh, Maliheh Nazari, Lutgens, Esther, Wang, Shusheng, Olson, Eric N, Schober, Andreas, Weber, Christian
Published in Science signaling (08.12.2009)
Published in Science signaling (08.12.2009)
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Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis
Santovito, Donato, Egea, Virginia, Bidzhekov, Kiril, Natarelli, Lucia, Mourão, André, Blanchet, Xavier, Wichapong, Kanin, Aslani, Maria, Brunßen, Coy, Horckmans, Michael, Hristov, Michael, Geerlof, Arie, Lutgens, Esther, Daemen, Mat J A P, Hackeng, Tilman, Ries, Christian, Chavakis, Triantafyllos, Morawietz, Henning, Naumann, Ronald, von Hundelshausen, Philipp, Steffens, Sabine, Duchêne, Johan, Megens, Remco T A, Sattler, Michael, Weber, Christian
Published in Science translational medicine (03.06.2020)
Published in Science translational medicine (03.06.2020)
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Distribution of macrophage polarization markers in human atherosclerosis
Stöger, J. Lauran, Gijbels, Marion J.J, van der Velden, Saskia, Manca, Marco, van der Loos, Chris M, Biessen, Erik A.L, Daemen, Mat J.A.P, Lutgens, Esther, de Winther, Menno P.J
Published in Atherosclerosis (01.12.2012)
Published in Atherosclerosis (01.12.2012)
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Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans
Remie, Carlijn ME, Roumans, Kay HM, Moonen, Michiel PB, Connell, Niels J, Havekes, Bas, Mevenkamp, Julian, Lindeboom, Lucas, de Wit, Vera HW, van de Weijer, Tineke, Aarts, Suzanne ABM, Lutgens, Esther, Schomakers, Bauke V, Elfrink, Hyung L, Zapata-Pérez, Rubén, Houtkooper, Riekelt H, Auwerx, Johan, Hoeks, Joris, Schrauwen-Hinderling, Vera B, Phielix, Esther, Schrauwen, Patrick
Published in The American journal of clinical nutrition (01.08.2020)
Published in The American journal of clinical nutrition (01.08.2020)
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Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis
DÖRING, Yvonne, MANTHEY, Helga D, DAEMEN, Mat J, LUTGENS, Esther, ZENKE, Martin, BINDER, Christoph J, WEBER, Christian, ZERNECKE, Alma, DRECHSLER, Maik, LIEVENS, Dirk, MEGENS, Remco T. A, SOEHNLEIN, Oliver, BUSCH, Martin, MANCA, Marco, KOENEN, Rory R, PELISEK, Jaroslav
Published in Circulation (New York, N.Y.) (03.04.2012)
Published in Circulation (New York, N.Y.) (03.04.2012)
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Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
Baardman, Jeroen, Verberk, Sanne G. S., van der Velden, Saskia, Gijbels, Marion J. J., van Roomen, Cindy P. P. A., Sluimer, Judith C., Broos, Jelle Y., Griffith, Guillermo R., Prange, Koen H. M., van Weeghel, Michel, Lakbir, Soufyan, Molenaar, Douwe, Meinster, Elisa, Neele, Annette E., Kooij, Gijs, de Vries, Helga E., Lutgens, Esther, Wellen, Kathryn E., de Winther, Menno P. J., Van den Bossche, Jan
Published in Nature communications (08.12.2020)
Published in Nature communications (08.12.2020)
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A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia
Baardman, Jeroen, Verberk, Sanne G.S., Prange, Koen H.M., van Weeghel, Michel, van der Velden, Saskia, Ryan, Dylan G., Wüst, Rob C.I., Neele, Annette E., Speijer, Dave, Denis, Simone W., Witte, Maarten E., Houtkooper, Riekelt H., O’neill, Luke A., Knatko, Elena V., Dinkova-Kostova, Albena T., Lutgens, Esther, de Winther, Menno P.J., Van den Bossche, Jan
Published in Cell reports (Cambridge) (20.11.2018)
Published in Cell reports (Cambridge) (20.11.2018)
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The Link between Hematopoiesis and Atherosclerosis
de Winther, Menno P.J, Lutgens, Esther
Published in The New England journal of medicine (09.05.2019)
Published in The New England journal of medicine (09.05.2019)
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Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease
Lacy, Michael, Bürger, Christina, Shami, Annelie, Ahmadsei, Maiwand, Winkels, Holger, Nitz, Katrin, van Tiel, Claudia M., Seijkens, Tom T. P., Kusters, Pascal J. H., Karshovka, Ela, Prange, Koen H. M., Wu, Yuting, Brouns, Sanne L. N., Unterlugauer, Sigrid, Kuijpers, Marijke J. E., Reiche, Myrthe E., Steffens, Sabine, Edsfeldt, Andreas, Megens, Remco T. A., Heemskerk, Johan W. M., Goncalves, Isabel, Weber, Christian, Gerdes, Norbert, Atzler, Dorothee, Lutgens, Esther
Published in Nature communications (18.06.2021)
Published in Nature communications (18.06.2021)
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Hypercholesterolemia-induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis
Seijkens, Tom, Hoeksema, Marten A, Beckers, Linda, Smeets, Esther, Meiler, Svenja, Levels, Johannes, Tjwa, Marc, de Winther, Menno P J, Lutgens, Esther
Published in The FASEB journal (01.05.2014)
Published in The FASEB journal (01.05.2014)
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Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology
Tuñón, José, Badimón, Lina, Bochaton-Piallat, Marie-Luce, Cariou, Bertrand, Daemen, Mat J, Egido, Jesus, Evans, Paul C, Hoefer, Imo E, Ketelhuth, Daniel F J, Lutgens, Esther, Matter, Christian M, Monaco, Claudia, Steffens, Sabine, Stroes, Erik, Vindis, Cécile, Weber, Christian, Bäck, Magnus
Published in Cardiovascular research (01.01.2019)
Published in Cardiovascular research (01.01.2019)
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Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure
Heymans, Stephane, Corsten, Maarten F., Verhesen, Wouter, Carai, Paolo, van Leeuwen, Rick E.W., Custers, Kevin, Peters, Tim, Hazebroek, Mark, Stöger, Lauran, Wijnands, Erwin, Janssen, Ben J., Creemers, Esther E., Pinto, Yigal M., Grimm, Dirk, Schürmann, Nina, Vigorito, Elena, Thum, Thomas, Stassen, Frank, Yin, Xiaoke, Mayr, Manuel, de Windt, Leon J., Lutgens, Esther, Wouters, Kristiaan, de Winther, Menno P.J., Zacchigna, Serena, Giacca, Mauro, van Bilsen, Marc, Papageorgiou, Anna-Pia, Schroen, Blanche
Published in Circulation (New York, N.Y.) (24.09.2013)
Published in Circulation (New York, N.Y.) (24.09.2013)
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CD40 Ligand+ Microparticles From Human Atherosclerotic Plaques Stimulate Endothelial Proliferation and Angiogenesis
Leroyer, Aurélie S., PhD, Rautou, Pierre-Emmanuel, MD, Silvestre, Jean-Sébastien, PhD, Castier, Yves, MD, PhD, Lesèche, Guy, MD, PhD, Devue, Cécile, BSc, Duriez, Micheline, BSc, Brandes, Ralf P., MD, PhD, Lutgens, Esther, MD, PhD, Tedgui, Alain, PhD, Boulanger, Chantal M., PhD
Published in Journal of the American College of Cardiology (14.10.2008)
Published in Journal of the American College of Cardiology (14.10.2008)
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