FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy
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Published in PloS one (03.11.2010)
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Detection of multiple mutations in urinary exfoliated cells from male bladder cancer patients at diagnosis and during follow-up
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Daniels, Marc, Lurkin, Irene, Pauli, Roland, Erbstößer, Erhard, Hildebrandt, Uwe, Hellwig, Karsten, Zschille, Uwe, Lüders, Petra, Krüger, Gabriele, Knolle, Jürgen, Stengel, Bernd, Prall, Friedrich, Hertel, Kay, Lobeck, Hartmut, Popp, Brigitte, Theissig, Franz, Wünsch, Peter, Zwarthoff, Ellen, Agaimy, Abbas, Schneider-Stock, Regine
Published in Cancer letters (15.12.2011)
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Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes
Lurkin, Irene, Stoehr, Robert, Hurst, Carolyn D, van Tilborg, Angela A G, Knowles, Margaret A, Hartmann, Arndt, Zwarthoff, Ellen C
Published in PloS one (21.01.2010)
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A reported 20-gene expression signature to predict lymph node-positive disease at radical cystectomy for muscle-invasive bladder cancer is clinically not applicable
van Kessel, Kim E M, van de Werken, Harmen J G, Lurkin, Irene, Ziel-van der Made, Angelique C J, Zwarthoff, Ellen C, Boormans, Joost L
Published in PloS one (20.03.2017)
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A Simple and Fast Method for the Simultaneous Detection of Nine Fibroblast Growth Factor Receptor 3 Mutations in Bladder Cancer and Voided Urine
VAN OERS, Johanna M. M, LURKIN, Irene, VAN EXSEL, Antonius J. A, NIJSEN, Yvette, VAN RHIJN, Bas W. G, VAN DER AA, Madelon N. M, ZWARTHOFF, Ellen C
Published in Clinical cancer research (01.11.2005)
Published in Clinical cancer research (01.11.2005)
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Immunohistochemical and genetic profiles of endometrioid endometrial carcinoma arising from atrophic endometrium
Geels, Yvette P, van der Putten, Louis J.M, van Tilborg, Angela A.G, Lurkin, Irene, Zwarthoff, Ellen C, Pijnenborg, Johanna M.A, van den Berg-van Erp, Saskia H, Snijders, Marc P.L.M, Bulten, Johan, Visscher, Daniel W, Dowdy, Sean C, Massuger, Leon F.A.G
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Selection of microsatellite markers for bladder cancer diagnosis without the need for corresponding blood
van Tilborg, Angela A G, Kompier, Lucie C, Lurkin, Irene, Poort, Ricardo, El Bouazzaoui, Samira, van der Keur, Kirstin, Zuiverloon, Tahlita, Dyrskjot, Lars, Orntoft, Torben F, Roobol, Monique J, Zwarthoff, Ellen C
Published in PloS one (22.08.2012)
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Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders
van Rhijn, Bas W G, van Tilborg, Angela A G, Lurkin, Irene, Bonaventure, Jacky, de Vries, Annie, Thiery, Jean-Paul, van der Kwast, Theodorus H, Zwarthoff, Ellen C, Radvanyi, Francois
Published in European journal of human genetics : EJHG (01.12.2002)
Published in European journal of human genetics : EJHG (01.12.2002)
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Combined Microsatellite and FGFR3 Mutation Analysis Enables a Highly Sensitive Detection of Urothelial Cell Carcinoma in Voided Urine
VAN RHIJN, Bas W. G, LURKIN, Irene, CHOPIN, Dominique K, KIRKELS, Wim J, THIERY, Jean-Paul, VAN DER KWAST, Theo H, RADVANYI, Francois, ZWARTHOFF, Ellen C
Published in Clinical cancer research (01.01.2003)
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Published in Clinical cancer research (01.01.2003)
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Validation of a DNA Methylation-Mutation Urine Assay to Select Patients with Hematuria for Cystoscopy
van Kessel, Kim E.M, Beukers, Willemien, Lurkin, Irene, Ziel-van der Made, Angelique, van der Keur, Kirstin A, Boormans, Joost L, Dyrskjøt, Lars, Márquez, Mirari, Ørntoft, Torben F, Real, Francisco X, Segersten, Ulrika, Malats, Núria, Malmström, Per-Uno, Van Criekinge, Wim, Zwarthoff, Ellen C
Published in The Journal of urology (01.03.2017)
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Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome
Allory, Yves, Beukers, Willemien, Sagrera, Ana, Flández, Marta, Marqués, Miriam, Márquez, Mirari, van der Keur, Kirstin A, Dyrskjot, Lars, Lurkin, Irene, Vermeij, Marcel, Carrato, Alfredo, Lloreta, Josep, Lorente, José A, Carrillo-de Santa Pau, Enrique, Masius, Roy G, Kogevinas, Manolis, Steyerberg, Ewout W, van Tilborg, Angela A.G, Abas, Cheno, Orntoft, Torben F, Zuiverloon, Tahlita C.M, Malats, Núria, Zwarthoff, Ellen C, Real, Francisco X
Published in European urology (01.02.2014)
Published in European urology (01.02.2014)
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Keratinocytic epidermal nevi are associated with mosaic RAS mutations
Hafner, Christian, Toll, Agusti, Gantner, Susanne, Mauerer, Andreas, Lurkin, Irene, Acquadro, Francesco, Fernández-Casado, Alejandro, Zwarthoff, Ellen C, Dietmaier, Wolfgang, Baselga, Eulalia, Parera, Elisabet, Vicente, Asunción, Casanova, Ariel, Cigudosa, Juan, Mentzel, Thomas, Pujol, Ramon M, Landthaler, Michael, Real, Francisco X
Published in Journal of medical genetics (01.04.2012)
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Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer
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Published in Human molecular genetics (15.10.2014)
Published in Human molecular genetics (15.10.2014)
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Defined morphological criteria allow reliable diagnosis of colorectal serrated polyps and predict polyp genetics
Rau, Tilman T., Agaimy, Abbas, Gehoff, Anastasia, Geppert, Carol, Jung, Klaus, Knobloch, Katharina, Langner, Cord, Lugli, Alessandro, Groenbus-Lurkin, Irene, Nagtegaal, Iris D., Rüschoff, Josef, Saegert, Xavier, Sarbia, Mario, Schneider-Stock, Regine, Vieth, Michael, Zwarthoff, Ellen C., Hartmann, Arndt
Published in Virchows Archiv : an international journal of pathology (01.06.2014)
Published in Virchows Archiv : an international journal of pathology (01.06.2014)
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Hotspot mutations in PIK3CA associate with first-line treatment outcome for aromatase inhibitors but not for tamoxifen
Ramirez-Ardila, Diana E., Helmijr, Jean C., Look, Maxime P., Lurkin, Irene, Ruigrok-Ritstier, Kirsten, van Laere, Steven, Dirix, Luc, Sweep, Fred C., Span, Paul N., Linn, Sabine C., Foekens, John A., Sleijfer, Stefan, Berns, Els M. J. J., Jansen, Maurice P. H. M.
Published in Breast cancer research and treatment (01.05.2013)
Published in Breast cancer research and treatment (01.05.2013)
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KRAS and BRAF mutation analysis in routine molecular diagnostics: comparison of three testing methods on formalin-fixed, paraffin-embedded tumor-derived DNA
Heideman, Daniëlle A M, Lurkin, Irene, Doeleman, Marije, Smit, Egbert F, Verheul, Henk M, Meijer, Gerrit A, Snijders, Peter J F, Thunnissen, Erik, Zwarthoff, Ellen C
Published in The Journal of molecular diagnostics : JMD (01.05.2012)
Published in The Journal of molecular diagnostics : JMD (01.05.2012)
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Abstract 549: A urine based assay to select patients for initial cystoscopy
van Kessel, Kim E.M., Beukers, Willemien, Lurkin, Irene, van der Keur, Kirstin A., Dyrskjot, Lars, Segersten, Ulrika, Ørntoft, Torben F., Malats, Nuria, Malmström, Per-Uno, Real, Francisco X., Bangma, Chris H., Zwarthoff, Ellen C.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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A urine based assay to select patients for initial cystoscopy
van Kessel, Kim E. M., Beukers, Willemien, Lurkin, Irene, van der Keur, Kirstin A., Dyrskjot, Lars, Segersten, Ulrika, Orntoft, Torben F., Malats, Nuria, Malmstrom, Per-Uno, Real, Francisco X., Bangma, Chris H., Zwarthoff, Ellen C.
Published in Cancer research (Chicago, Ill.) (2015)
Published in Cancer research (Chicago, Ill.) (2015)
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