Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation
Glassman, Caleb R, Tsutsumi, Naotaka, Saxton, Robert A, Lupardus, Patrick J, Jude, Kevin M, Garcia, K Christopher
Published in Science (American Association for the Advancement of Science) (08.04.2022)
Published in Science (American Association for the Advancement of Science) (08.04.2022)
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Journal Article
Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition
Lupardus, Patrick J., Ultsch, Mark, Wallweber, Heidi, Kohli, Pawan Bir, Johnson, Adam R., Eigenbrot, Charles
Published in Proceedings of the National Academy of Sciences - PNAS (03.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (03.06.2014)
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Journal Article
The Structural Basis for Class II Cytokine Receptor Recognition by JAK1
Ferrao, Ryan, Wallweber, Heidi J.A., Ho, Hoangdung, Tam, Christine, Franke, Yvonne, Quinn, John, Lupardus, Patrick J.
Published in Structure (London) (07.06.2016)
Published in Structure (London) (07.06.2016)
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Journal Article
Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function
Hackos, David H., Lupardus, Patrick J., Grand, Teddy, Chen, Yelin, Wang, Tzu-Ming, Reynen, Paul, Gustafson, Amy, Wallweber, Heidi J.A., Volgraf, Matthew, Sellers, Benjamin D., Schwarz, Jacob B., Paoletti, Pierre, Sheng, Morgan, Zhou, Qiang, Hanson, Jesse E.
Published in Neuron (Cambridge, Mass.) (02.03.2016)
Published in Neuron (Cambridge, Mass.) (02.03.2016)
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Journal Article
Structural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane Complex
Skiniotis, Georgios, Lupardus, Patrick J., Martick, Monika, Walz, Thomas, Garcia, K. Christopher
Published in Molecular cell (05.09.2008)
Published in Molecular cell (05.09.2008)
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Journal Article
Monoubiquitination of Proliferating Cell Nuclear Antigen Induced by Stalled Replication Requires Uncoupling of DNA Polymerase and Mini-chromosome Maintenance Helicase Activities
Chang, Debbie J., Lupardus, Patrick J., Cimprich, Karlene A.
Published in The Journal of biological chemistry (27.10.2006)
Published in The Journal of biological chemistry (27.10.2006)
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Journal Article
A requirement for replication in activation of the ATR-dependent DNA damage checkpoint
Lupardus, Patrick J, Byun, Tony, Yee, Muh-Ching, Hekmat-Nejad, Mohammad, Cimprich, Karlene A
Published in Genes & development (15.09.2002)
Published in Genes & development (15.09.2002)
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Journal Article
Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells
Glassman, Caleb R., Mathiharan, Yamuna Kalyani, Jude, Kevin M., Su, Leon, Panova, Ouliana, Lupardus, Patrick J., Spangler, Jamie B., Ely, Lauren K., Thomas, Christoph, Skiniotis, Georgios, Garcia, K. Christopher
Published in Cell (18.02.2021)
Published in Cell (18.02.2021)
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Journal Article
Fanconi Anemia Proteins Are Required To Prevent Accumulation of Replication-Associated DNA Double-Strand Breaks
Sobeck, Alexandra, Stone, Stacie, Costanzo, Vincenzo, de Graaf, Bendert, Reuter, Tanja, de Winter, Johan, Wallisch, Michael, Akkari, Yassmine, Olson, Susan, Wang, Weidong, Joenje, Hans, Christian, Jan L., Lupardus, Patrick J., Cimprich, Karlene A., Gautier, Jean, Hoatlin, Maureen E.
Published in Molecular and Cellular Biology (01.01.2006)
Published in Molecular and Cellular Biology (01.01.2006)
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Journal Article
Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability
Lauffer, Benjamin E.L., Mintzer, Robert, Fong, Rina, Mukund, Susmith, Tam, Christine, Zilberleyb, Inna, Flicke, Birgit, Ritscher, Allegra, Fedorowicz, Grazyna, Vallero, Roxanne, Ortwine, Daniel F., Gunzner, Janet, Modrusan, Zora, Neumann, Lars, Koth, Christopher M., Lupardus, Patrick J., Kaminker, Joshua S., Heise, Christopher E., Steiner, Pascal
Published in The Journal of biological chemistry (13.09.2013)
Published in The Journal of biological chemistry (13.09.2013)
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Journal Article
Membrane-delimited coupling between sigma receptors and K+ channels in rat neurohypophysial terminals requires neither G-protein nor ATP
Lupardus, Patrick J., Wilke, Russell A., Aydar, Ebru, Palmer, Chris P., Chen, Yuenmu, Ruoho, Arnold E., Jackson, Meyer B.
Published in The Journal of physiology (01.08.2000)
Published in The Journal of physiology (01.08.2000)
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Journal Article
Structural investigation of human S. aureus-targeting antibodies that bind wall teichoic acid
Fong, Rina, Kajihara, Kimberly, Chen, Matthew, Hotzel, Isidro, Mariathasan, Sanjeev, Hazenbos, Wouter L W, Lupardus, Patrick J
Published in mAbs (01.10.2018)
Published in mAbs (01.10.2018)
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