Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers
Hatzivassiliou, Georgia, Haling, Jacob R., Chen, Huifen, Song, Kyung, Price, Steve, Heald, Robert, Hewitt, Joanne F. M., Zak, Mark, Peck, Ariana, Orr, Christine, Merchant, Mark, Hoeflich, Klaus P., Chan, Jocelyn, Luoh, Shiuh-Ming, Anderson, Daniel J., Ludlam, Mary J. C., Wiesmann, Christian, Ultsch, Mark, Friedman, Lori S., Malek, Shiva, Belvin, Marcia
Published in Nature (London) (12.09.2013)
Published in Nature (London) (12.09.2013)
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Journal Article
Activating Smoothened mutations in sporadic basal-cell carcinoma
Jr, Ervin H. Epstein, de Sauvage, Frederic J, Xie, Jingwu, Murone, Maximilien, Luoh, Shiuh-Ming, Ryan, Anne, Gu, Qimin, Zhang, Chaohui, Bonifas, Jeannette M, Lam, Ching-Wan, Hynes, Mary, Goddard, Audrey, Rosenthal, Arnon
Published in Nature (London) (01.01.1998)
Published in Nature (London) (01.01.1998)
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Journal Article
Loss of the Serine/Threonine Kinase Fused Results in Postnatal Growth Defects and Lethality Due to Progressive Hydrocephalus
Merchant, Mark, Evangelista, Marie, Luoh, Shiuh-Ming, Frantz, Gretchen D., Chalasani, Sreedevi, Carano, Richard A. D., van Hoy, Marjie, Ramirez, Julio, Ogasawara, Annie K., McFarland, Leanne M., Filvaroff, Ellen H., French, Dorothy M., de Sauvage, Frederic J.
Published in Molecular and Cellular Biology (01.08.2005)
Published in Molecular and Cellular Biology (01.08.2005)
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Journal Article
Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
Stone, D M, Murone, M, Luoh, S, Ye, W, Armanini, M P, Gurney, A, Phillips, H, Brush, J, Goddard, A, de Sauvage, F J, Rosenthal, A
Published in Journal of cell science (01.12.1999)
Published in Journal of cell science (01.12.1999)
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Journal Article
Gli regulation by the opposing activities of Fused and Suppressor of Fused
de Sauvage, Frederic J, Murone, Maximilien, Luoh, Shiuh-Ming, Stone, Donna, Li, Wenlu, Gurney, Austin, Armanini, Mark, Grey, Christa, Rosenthal, Arnon
Published in Nature cell biology (01.05.2000)
Published in Nature cell biology (01.05.2000)
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Journal Article
Mutations of the Growth Hormone Receptor in Children with Idiopathic Short Stature
Goddard, Audrey D, Covello, Robin, Luoh, Shiuh-Ming, Clackson, Tim, Attie, Kenneth M, Gesundheit, Neil, Rundle, Amy Chen, Wells, James A, Carlsson, Lena M.S
Published in The New England journal of medicine (26.10.1995)
Published in The New England journal of medicine (26.10.1995)
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Journal Article
GEPIS—quantitative gene expression profiling in normal and cancer tissues
Zhang, Yan, Eberhard, David A., Frantz, Gretchen D., Dowd, Patrick, Wu, Thomas D., Zhou, Yan, Watanabe, Colin, Luoh, Shiuh-Ming, Polakis, Paul, Hillan, Kenneth J., Wood, William I., Zhang, Zemin
Published in Bioinformatics (12.10.2004)
Published in Bioinformatics (12.10.2004)
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Journal Article
Role of the Distal Half of the c-Mpl Intracellular Domain in Control of Platelet Production by Thrombopoietin In Vivo
Luoh, Shiuh-Ming, Stefanich, Eric, Solar, Gregg, Steinmetz, Hope, Lipari, Terry, Pestina, Tamara I., Jackson, Carl W., de Sauvage, Frederic J.
Published in Molecular and Cellular Biology (01.01.2000)
Published in Molecular and Cellular Biology (01.01.2000)
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Journal Article
Cloning of FRK, a novel human intracellular SRC-like tyrosine kinaseencoding gene
Lee, James, Wang, Zhengyu, Luoh, Shiuh-Ming, Wood, William I., Scadden, David T.
Published in Gene (01.01.1994)
Published in Gene (01.01.1994)
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Journal Article
Vascular Endothelial Growth Factor-Related Protein: A Ligand and Specific Activator of the Tyrosine Kinase Receptor Flt4
Lee, James, Gray, Alane, Yuan, Jean, Luoh, Shiuh-Ming, Avraham, Hava, Wood, William I.
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.1996)
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Journal Article
Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin
de Sauvage, F J, Carver-Moore, K, Luoh, S M, Ryan, A, Dowd, M, Eaton, D L, Moore, M W
Published in The Journal of experimental medicine (01.02.1996)
Published in The Journal of experimental medicine (01.02.1996)
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Journal Article
Expression Cloning of Cardiotrophin 1, a Cytokine that Induces Cardiac Myocyte Hypertrophy
Pennica, Diane, King, Kathleen L., Shaw, Kenneth J., Luis, Elizabeth, Rullamas, Janette, Luoh, Shiuh-Ming, Darbonne, Walter C., Knutzon, Deborah S., Yen, Randy, Chien, Kenneth R., Baker, Joffre B., Wood, William I.
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.1995)
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.1995)
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Journal Article
Low Levels of Erythroid and Myeloid Progenitors in Thrombopoietin-and c-mpl-Deficient Mice
Carver-Moore, Karen, Broxmeyer, Hal E., Luoh, Shiuh-Ming, Cooper, Scott, Peng, Jipeng, Burstein, Samuel A., Moore, Mark W., Sauvage, Frederic J. de
Published in Blood (01.08.1996)
Published in Blood (01.08.1996)
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Journal Article
Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis
YAN ZHOU, LUOH, Shiuh-Ming, YAN ZHANG, WATANABE, Colin, WU, Thomas D, OSTLAND, Michael, WOOD, William I, ZEMIN ZHANG
Published in Cancer research (Chicago, Ill.) (15.09.2003)
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Published in Cancer research (Chicago, Ill.) (15.09.2003)
Journal Article
Abstract 4898: Effects of chemotherapeutic agents on the tumor immune microenvironment
Belvin, Marcia P., Luoh, Shiuh-Ming, Cheung, Jeanne, McNamara, Erin, Cubas, Rafael, Kim, Jeong
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 4905: Effects of MAPK pathway inhibitors in the tumor immune microenvironment
Belvin, Marcia P., Williams, Erin, Luoh, Shiuh-Ming, Cheung, Jeanne, Orr, Christine, Chan, Emily, Ebert, Peter, Mellman, Ira, Kim, Jeong, Merchant, Mark
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 2340: Preferential targeting of KRAS mutant or BRAF mutant tumors using MEK inhibitors with distinct mechanisms of action
Hatzivassiliou, Georgia, Haling, Jacob, Chen, Huifen, Song, Kyung, Luoh, Shiuh-Ming, Price, Steve, Heald, Robert, Zak, Mark, Merchant, Mark, Hoeflich, Klaus, Friedman, Lori, Malek, Shiva, Belvin, Marcia P.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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