Progress in PD-1/PD-L1 pathway inhibitors: From biomacromolecules to small molecules
Lin, Xin, Lu, Xiang, Luo, Guoshun, Xiang, Hua
Published in European journal of medicinal chemistry (15.01.2020)
Published in European journal of medicinal chemistry (15.01.2020)
Get full text
Journal Article
Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo
Luo, Guoshun, Li, Zhenbang, Lin, Xin, Li, Xinyu, Chen, Yu, Xi, Kun, Xiao, Maoxu, Wei, Hanlin, Zhu, Lizhe, Xiang, Hua
Published in Acta pharmaceutica Sinica. B (01.05.2021)
Published in Acta pharmaceutica Sinica. B (01.05.2021)
Get full text
Journal Article
Catalytic Enantioselective Allylations of Acetylenic Aldehydes via 2‑Propanol-Mediated Reductive Coupling
Brito, Gilmar A, Della-Felice, Franco, Luo, Guoshun, Burns, Alexander S, Pilli, Ronaldo A, Rychnovsky, Scott D, Krische, Michael J
Published in Organic letters (06.07.2018)
Published in Organic letters (06.07.2018)
Get full text
Journal Article
Precisely Amplifying Intracellular Oxidative Storm by Metal–Organic Coordination Polymers to Augment Anticancer Immunity
Li, Shangfei, Chen, Xing, Guan, Shuo, Wang, Zhiyuan, Cao, Wuji, Luo, Guoshun, Ling, Xiang
Published in ACS nano (08.08.2023)
Published in ACS nano (08.08.2023)
Get full text
Journal Article
Discovery and Proof of Concept of Potent Dual Polθ/PARP Inhibitors for Efficient Treatment of Homologous Recombination-Deficient Tumors
Ma, Luyu, Chen, Wei, Yang, Ming, Ha, Si, Xiong, Shuangshuang, Zhu, Jiacheng, Xiang, Hua, Luo, Guoshun
Published in Journal of medicinal chemistry (14.03.2024)
Published in Journal of medicinal chemistry (14.03.2024)
Get full text
Journal Article
Development of novel tetrahydroisoquinoline-hydroxamate conjugates as potent dual SERDs/HDAC inhibitors for the treatment of breast cancer
Luo, Guoshun, Lin, Xin, Ren, Shengnan, Wu, Shuangjie, Wang, Xin, Ma, Luyu, Xiang, Hua
Published in European journal of medicinal chemistry (15.12.2021)
Published in European journal of medicinal chemistry (15.12.2021)
Get full text
Journal Article
Design and synthesis of novel benzothiophene analogs as selective estrogen receptor covalent antagonists against breast cancer
Bai, Chengfeng, Ren, Shengnan, Wu, Shuangjie, Zhu, Meiqi, Luo, Guoshun, Xiang, Hua
Published in European journal of medicinal chemistry (05.10.2021)
Published in European journal of medicinal chemistry (05.10.2021)
Get full text
Journal Article
Structure–Activity Relationship (SAR) Studies of Novel Monovalent AR/AR-V7 Dual Degraders with Potent Efficacy against Advanced Prostate Cancer
Xiao, Maoxu, Ha, Si, Zhu, Jiacheng, Tao, Wenxiang, Fu, Zixuan, Wei, Hanlin, Hou, Qiangqiang, Luo, Guoshun, Xiang, Hua
Published in Journal of medicinal chemistry (11.04.2024)
Published in Journal of medicinal chemistry (11.04.2024)
Get full text
Journal Article
Structure-activity relationships of 2, 4-disubstituted pyrimidines as dual ERα/VEGFR-2 ligands with anti-breast cancer activity
Luo, Guoshun, Tang, Zhichao, Lao, Kejing, Li, Xinyu, You, Qidong, Xiang, Hua
Published in European journal of medicinal chemistry (25.04.2018)
Published in European journal of medicinal chemistry (25.04.2018)
Get full text
Journal Article
Synthesis and evaluation of novel thiosemicarbazone and semicarbazone analogs with both anti-proliferative and anti-metastatic activities against triple negative breast cancer
Bai, Chengfeng, Wu, Shuangjie, Ren, Shengnan, Zhu, Meiqi, Luo, Guoshun, Xiang, Hua
Published in Bioorganic & medicinal chemistry (01.05.2021)
Published in Bioorganic & medicinal chemistry (01.05.2021)
Get full text
Journal Article