Current Challenges and Trends in the Discovery of Agrochemicals
Lamberth, Clemens, Jeanmart, Stephane, Luksch, Torsten, Plant, Andrew
Published in Science (American Association for the Advancement of Science) (16.08.2013)
Published in Science (American Association for the Advancement of Science) (16.08.2013)
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Artificial intelligence in chemistry and drug design
Brown, Nathan, Ertl, Peter, Lewis, Richard, Luksch, Torsten, Reker, Daniel, Schneider, Nadine
Published in Journal of computer-aided molecular design (01.07.2020)
Published in Journal of computer-aided molecular design (01.07.2020)
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A dispensable paralog of succinate dehydrogenase subunit C mediates standing resistance towards a subclass of SDHI fungicides in Zymoseptoria tritici
Steinhauer, Diana, Salat, Marie, Frey, Regula, Mosbach, Andreas, Luksch, Torsten, Balmer, Dirk, Hansen, Rasmus, Widdison, Stephanie, Logan, Grace, Dietrich, Robert A, Kema, Gert H J, Bieri, Stephane, Sierotzki, Helge, Torriani, Stefano F F, Scalliet, Gabriel
Published in PLoS pathogens (01.12.2019)
Published in PLoS pathogens (01.12.2019)
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Mutagenesis and functional studies with succinate dehydrogenase inhibitors in the wheat pathogen Mycosphaerella graminicola
Scalliet, Gabriel, Bowler, Judith, Luksch, Torsten, Kirchhofer-Allan, Lucy, Steinhauer, Diana, Ward, Keith, Niklaus, Michael, Verras, Andreas, Csukai, Michael, Daina, Antoine, Fonné-Pfister, Raymonde
Published in PloS one (19.04.2012)
Published in PloS one (19.04.2012)
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Journal Article
Automated patent classification for crop protection via domain adaptation
Christofidellis, Dimitrios, Lehmann, Marzena Maria, Luksch, Torsten, Stenta, Marco, Manica, Matteo
Published in Applied AI Letters (01.02.2023)
Published in Applied AI Letters (01.02.2023)
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Journal Article
Screening a protein kinase inhibitor library against Plasmodium falciparum
Hallyburton, Irene, Grimaldi, Raffaella, Woodland, Andrew, Baragaña, Beatriz, Luksch, Torsten, Spinks, Daniel, James, Daniel, Leroy, Didier, Waterson, David, Fairlamb, Alan H, Wyatt, Paul G, Gilbert, Ian H, Frearson, Julie A
Published in Malaria journal (07.11.2017)
Published in Malaria journal (07.11.2017)
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Synthesis of 2,3,4,7-tetrahydro-1H-azepines as privileged ligand scaffolds for the design of aspartic protease inhibitors via a ring-closing metathesis approach
Brass, Sascha, Chan, Nan-Si, Gerlach, Christof, Luksch, Torsten, Boettcher, Jark, Diederich, Wlibke E.
Published in Journal of organometallic chemistry (01.12.2006)
Published in Journal of organometallic chemistry (01.12.2006)
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The Design and Synthesis of Potent and Selective Inhibitors of Trypanosoma brucei Glycogen Synthase Kinase 3 for the Treatment of Human African Trypanosomiasis
Urich, Robert, Grimaldi, Raffaella, Luksch, Torsten, Frearson, Julie A, Brenk, Ruth, Wyatt, Paul G
Published in Journal of medicinal chemistry (25.09.2014)
Published in Journal of medicinal chemistry (25.09.2014)
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Journal Article
Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode
Spinks, Daniel, Smith, Victoria, Thompson, Stephen, Robinson, David A., Luksch, Torsten, Smith, Alasdair, Torrie, Leah S., McElroy, Stuart, Stojanovski, Laste, Norval, Suzanne, Collie, Iain T., Hallyburton, Irene, Rao, Bhavya, Brand, Stephen, Brenk, Ruth, Frearson, Julie A., Read, Kevin D., Wyatt, Paul G., Gilbert, Ian H.
Published in ChemMedChem (01.11.2015)
Published in ChemMedChem (01.11.2015)
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Journal Article
Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3
Cleghorn, Laura A. T., Woodland, Andrew, Collie, Iain T., Torrie, Leah S., Norcross, Neil, Luksch, Torsten, Mpamhanga, Chido, Walker, Roderick G., Mottram, Jeremy C., Brenk, Ruth, Frearson, Julie A., Gilbert, Ian H., Wyatt, Paul G.
Published in ChemMedChem (09.12.2011)
Published in ChemMedChem (09.12.2011)
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From On-Target to Off-Target Activity: Identification and Optimisation of Trypanosoma brucei GSK3 Inhibitors and Their Characterisation as Anti-Trypanosoma brucei Drug Discovery Lead Molecules
Woodland, Andrew, Grimaldi, Raffaella, Luksch, Torsten, Cleghorn, Laura A. T., Ojo, Kayode K., Van Voorhis, Wesley C., Brenk, Ruth, Frearson, Julie A., Gilbert, Ian H., Wyatt, Paul G.
Published in ChemMedChem (01.07.2013)
Published in ChemMedChem (01.07.2013)
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Correction: Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis
Baragaña, Beatriz, Hallyburton, Irene, Lee, Marcus C. S., Norcross, Neil R., Grimaldi, Raffaella, Otto, Thomas D., Proto, William R., Blagborough, Andrew M., Meister, Stephan, Wirjanata, Grennady, Ruecker, Andrea, Upton, Leanna M., Abraham, Tara S., Almeida, Mariana J., Pradhan, Anupam, Porzelle, Achim, Martínez, María Santos, Bolscher, Judith M., Woodland, Andrew, Luksch, Torsten, Norval, Suzanne, Zuccotto, Fabio, Thomas, John, Simeons, Frederick, Stojanovski, Laste, Osuna-Cabello, Maria, Brock, Paddy M., Churcher, Tom S., Sala, Katarzyna A., Zakutansky, Sara E., Jiménez-Díaz, María Belén, Sanz, Laura Maria, Riley, Jennifer, Basak, Rajshekhar, Campbell, Michael, Avery, Vicky M., Sauerwein, Robert W., Dechering, Koen J., Noviyanti, Rintis, Campo, Brice, Frearson, Julie A., Angulo-Barturen, Iñigo, Ferrer-Bazaga, Santiago, Gamo, Francisco Javier, Wyatt, Paul G., Leroy, Didier, Siegl, Peter, Delves, Michael J., Kyle, Dennis E., Wittlin, Sergio, Marfurt, Jutta, Price, Ric N., Sinden, Robert E., Winzeler, Elizabeth A., Charman, Susan A., Bebrevska, Lidiya, Gray, David W., Campbell, Simon, Fairlamb, Alan H., Willis, Paul A., Rayner, Julian C., Fidock, David A., Read, Kevin D., Gilbert, Ian H.
Published in Nature (London) (01.09.2016)
Published in Nature (London) (01.09.2016)
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Erratum: Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis
Baragaña, Beatriz, Hallyburton, Irene, Lee, Marcus C. S., Norcross, Neil R., Grimaldi, Raffaella, Otto, Thomas D., Proto, William R., Blagborough, Andrew M., Meister, Stephan, Wirjanata, Grennady, Ruecker, Andrea, Upton, Leanna M., Abraham, Tara S., Almeida, Mariana J., Pradhan, Anupam, Porzelle, Achim, Martínez, María Santos, Bolscher, Judith M., Woodland, Andrew, Luksch, Torsten, Norval, Suzanne, Zuccotto, Fabio, Thomas, John, Simeons, Frederick, Stojanovski, Laste, Osuna-Cabello, Maria, Brock, Paddy M., Churcher, Tom S., Sala, Katarzyna A., Zakutansky, Sara E., Jiménez-Díaz, María Belén, Sanz, Laura Maria, Riley, Jennifer, Basak, Rajshekhar, Campbell, Michael, Avery, Vicky M., Sauerwein, Robert W., Dechering, Koen J., Noviyanti, Rintis, Campo, Brice, Frearson, Julie A., Angulo-Barturen, Iñigo, Ferrer-Bazaga, Santiago, Gamo, Francisco Javier, Wyatt, Paul G., Leroy, Didier, Siegl, Peter, Delves, Michael J., Kyle, Dennis E., Wittlin, Sergio, Marfurt, Jutta, Price, Ric N., Sinden, Robert E., Winzeler, Elizabeth A., Charman, Susan A., Bebrevska, Lidiya, Gray, David W., Campbell, Simon, Fairlamb, Alan H., Willis, Paul A., Rayner, Julian C., Fidock, David A., Read, Kevin D., Gilbert, Ian H.
Published in Nature (London) (25.05.2016)
Published in Nature (London) (25.05.2016)
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Cover Picture: Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode (ChemMedChem 11/2015)
Spinks, Daniel, Smith, Victoria, Thompson, Stephen, Robinson, David A., Luksch, Torsten, Smith, Alasdair, Torrie, Leah S., McElroy, Stuart, Stojanovski, Laste, Norval, Suzanne, Collie, Iain T., Hallyburton, Irene, Rao, Bhavya, Brand, Stephen, Brenk, Ruth, Frearson, Julie A., Read, Kevin D., Wyatt, Paul G., Gilbert, Ian H.
Published in ChemMedChem (01.11.2015)
Published in ChemMedChem (01.11.2015)
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