A Novel Bispecific Antibody Targeting EGFR and cMet Is Effective against EGFR Inhibitor-Resistant Lung Tumors
Moores, Sheri L, Chiu, Mark L, Bushey, Barbara S, Chevalier, Kristen, Luistro, Leopoldo, Dorn, Keri, Brezski, Randall J, Haytko, Peter, Kelly, Thomas, Wu, Sheng-Jiun, Martin, Pauline L, Neijssen, Joost, Parren, Paul W H I, Schuurman, Janine, Attar, Ricardo M, Laquerre, Sylvie, Lorenzi, Matthew V, Anderson, G Mark
Published in Cancer research (Chicago, Ill.) (01.07.2016)
Published in Cancer research (Chicago, Ill.) (01.07.2016)
Get full text
Journal Article
A stable, engineered TL1A ligand co-stimulates T cells via specific binding to DR3
Zwolak, Adam, Chan, Szeman Ruby, Harvilla, Paul, Mahady, Sally, Armstrong, Anthony A, Luistro, Leopoldo, Tamot, Ninkka, Yamada, Douglas, Derebe, Mehabaw, Pomerantz, Steven, Chiu, Mark, Ganesan, Rajkumar, Chowdhury, Partha
Published in Scientific reports (29.11.2022)
Published in Scientific reports (29.11.2022)
Get full text
Journal Article
Blockade of VLA4 sensitizes leukemic and myeloma tumor cells to CD3 redirection in the bone marrow microenvironment
Nair-Gupta, Priyanka, Rudnick, Stephen I, Luistro, Leopoldo, Smith, Melissa, McDaid, Ronan, Li, Yingzhe, Pillarisetti, Kodandaram, Joseph, Jocelin, Heidrich, Bradley, Packman, Kathryn, Attar, Ricardo, Gaudet, François
Published in Blood cancer journal (New York) (01.06.2020)
Published in Blood cancer journal (New York) (01.06.2020)
Get full text
Journal Article
Discovery of siRNA Lipid Nanoparticles to Transfect Suspension Leukemia Cells and Provide In Vivo Delivery Capability
He, Wei, Bennett, Michael J, Luistro, Leopoldo, Carvajal, Daisy, Nevins, Thomas, Smith, Melissa, Tyagi, Gaurav, Cai, James, Wei, Xin, Lin, Tai-An, Heimbrook, David C, Packman, Kathryn, Boylan, John F
Published in Molecular therapy (01.02.2014)
Published in Molecular therapy (01.02.2014)
Get full text
Journal Article
Targeting of CD122 enhances antitumor immunity by altering the tumor immune environment
Villarreal, Daniel O, Allegrezza, Michael J, Smith, Melissa A, Chin, Diana, Luistro, Leopoldo L, Snyder, Linda A
Published in Oncotarget (12.12.2017)
Published in Oncotarget (12.12.2017)
Get full text
Journal Article
RG7212 Anti-TWEAK mAb Inhibits Tumor Growth through Inhibition of Tumor Cell Proliferation and Survival Signaling and by Enhancing the Host Antitumor Immune Response
XUEFENG YIN, LUISTRO, Leopoldo, XIAOQIAN WANG, PACKMAN, Kathryn, ROSINSKI, Jim, BERKOFSKY-FESSLER, Windy, TANG, Jian-Ping, PANT, Saumya, GEHO, David, VEGA-HARRING, Suzana, DEMARIO, Mark, LEVITSKY, Hy, HUA ZHONG, SIMCOX, Mary, SMITH, Melissa, NEVINS, Tom, SCHOSTACK, Kathleen, HILTON, Holly, LIN, Tai-An, TRUITT, Theresa, BIONDI, Denise
Published in Clinical cancer research (15.10.2013)
Published in Clinical cancer research (15.10.2013)
Get full text
Journal Article
In vitro and in vivo activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials
DePinto, Wanda, Chu, Xin-Jie, Yin, Xuefeng, Smith, Melissa, Packman, Kathryn, Goelzer, Petra, Lovey, Allen, Chen, Yingsi, Qian, Hong, Hamid, Rachid, Xiang, Qing, Tovar, Christian, Blain, Roger, Nevins, Tom, Higgins, Brian, Luistro, Leopoldo, Kolinsky, Kenneth, Felix, Bernardo, Hussain, Sazzad, Heimbrook, David
Published in Molecular cancer therapeutics (01.11.2006)
Published in Molecular cancer therapeutics (01.11.2006)
Get full text
Journal Article
Development and characterization of a preclinical ovarian carcinoma model to investigate the mechanism of acquired resistance to trastuzumab
LUISTRO, LEOPOLDO L, ROSINSKI, JAMES A, BIAN, HONGJIN, BISHAYEE, SUBAL, RAMESHWAR, PRANELA, PONZIO, NICHOLAS M, RITLAND, STEVE R
Published in International journal of oncology (01.08.2012)
Published in International journal of oncology (01.08.2012)
Get full text
Journal Article
A T-cell–redirecting bispecific G-protein–coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma
Pillarisetti, Kodandaram, Edavettal, Suzanne, Mendonça, Mark, Li, Yingzhe, Tornetta, Mark, Babich, Alexander, Majewski, Nate, Husovsky, Matt, Reeves, Dara, Walsh, Eileen, Chin, Diana, Luistro, Leopoldo, Joseph, Jocelin, Chu, Gerald, Packman, Kathryn, Shetty, Shoba, Elsayed, Yusri, Attar, Ricardo, Gaudet, François
Published in Blood (09.04.2020)
Published in Blood (09.04.2020)
Get full text
Journal Article
Characterization of JNJ-79635322, a Novel BCMAxGPRC5DxCD3 T-Cell Redirecting Trispecific Antibody, for the Treatment of Multiple Myeloma
Pillarisetti, Ram, Yang, Danlin, Yao, Jianhong, Smith, Melissa, Luistro, Leopoldo, Vulfson, Peter, Testa, James, Packman, Kathryn, Brodeur, Scott, Attar, Ricardo M., Elsayed, Yusri, Philippar, Ulrike
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
Get full text
Journal Article
Teclistamab is an active T cell–redirecting bispecific antibody against B-cell maturation antigen for multiple myeloma
Pillarisetti, Kodandaram, Powers, Gordon, Luistro, Leopoldo, Babich, Alexander, Baldwin, Eric, Li, Yingzhe, Zhang, Xiaochun, Mendonça, Mark, Majewski, Nate, Nanjunda, Rupesh, Chin, Diana, Packman, Kathryn, Elsayed, Yusri, Attar, Ricardo, Gaudet, François
Published in Blood advances (22.09.2020)
Published in Blood advances (22.09.2020)
Get full text
Journal Article
Discovery of a Novel, First-in-Class Bfl-1 BH3 Mimetic with Pro-Apoptotic Activity
Derks, Maarten, Bryan, Marian C., Rockx, Cindy, Schults, Tamara, Verhulst, Tinne, Pietrak, Beth, Maehigashi, Tatsuya, Robertson, James C., DeMaria, Andrew H., Holt, Kimberly, Ji, Shaofei, Wong, Victoria, Bueters, Ruud, Koo, Seong Joo, Masure, Stefan, Bhogal, Balpreet, Kelly, Christopher B., Mitra, Kaushik, Luistro, Leopoldo, Shaffer, Paul L., Szewczuk, Lawrence, Elsayed, Yusri, Philippar, Ulrike
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
Get full text
Journal Article
Discovery of JNJ-63576253: A Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC)
Zhang, Zhuming, Connolly, Peter J, Lim, Heng Keang, Pande, Vineet, Meerpoel, Lieven, Teleha, Christopher, Branch, Jonathan R, Ondrus, Janine, Hickson, Ian, Bush, Tammy, Luistro, Leopoldo, Packman, Kathryn, Bischoff, James R, Ibrahim, Salam, Parrett, Christopher, Chong, Yolanda, Gottardis, Marco M, Bignan, Gilles
Published in Journal of medicinal chemistry (28.01.2021)
Published in Journal of medicinal chemistry (28.01.2021)
Get full text
Journal Article
Antitumor activity of interleukin 12 in preclinical models
Brunda, M J, Luistro, L, Rumennik, L, Wright, R B, Dvorozniak, M, Aglione, A, Wigginton, J M, Wiltrout, R H, Hendrzak, J A, Palleroni, A V
Published in Cancer chemotherapy and pharmacology (01.01.1996)
Published in Cancer chemotherapy and pharmacology (01.01.1996)
Get more information
Journal Article
Preclinical Profile of a Potent γ-Secretase Inhibitor Targeting Notch Signaling with In vivo Efficacy and Pharmacodynamic Properties
LUISTRO, Leopoldo, WEI HE, LINN, Michael, FLOHR, Alexander, JAKOB-RØTNE, Roland, JACOBSEN, Helmut, GLENN, Kelli, HEIMBROOK, David, BOYLAN, John F, SMITH, Melissa, PACKMAN, Kathryn, VILENCHIK, Maria, CARVAJAL, Daisy, ROBERTS, John, CAI, James, BERKOFSKY-FESSLER, Windy, HILTON, Holly
Published in Cancer research (Chicago, Ill.) (01.10.2009)
Published in Cancer research (Chicago, Ill.) (01.10.2009)
Get full text
Journal Article
Abstract 5567: In vivo administration of the STING agonist, JNJ-67544412, leads to complete regression of established murine subcutaneous tumors
Smith, Melissa, Chin, Diana, Chan, Szeman, Mahady, Sally, Campion, Liam, Morgan, Caitlin, Patel, Shefali, Chu, Gerald, Hughes, Anna, Bignan, Gilles, Connolly, Pete, Emanuel, Stuart, Packman, Kathryn, Luistro, Leopoldo L.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Get full text
Journal Article
Abstract 3636: Potent antitumor activity of duvortuxizumab, a CD19 x CD3 DART® molecule, in lymphoma models
Izhak, Liat, Cullen, Dana E., Elgawly, Maha, Luistro, Leopoldo, Johnson, Syd, Bald, Jaime, Sasser, A Kate, Balasubramanian, Sriram
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Abstract 2179: Antitumor activity of JNJ-63576253 (TRC253), a small molecule antagonist of F877L mutant and wild-type androgen receptor
Bush, Tammy L., Ndikuyeze, Georges Habineza, Bignan, Gilles, Branch, Jonathan, Ondrus, Janine, Shi, Yifan, Luistro, Leopoldo, Hastings, James, Erhardt, Joseph, Hickson, Ian, Patel, Shefali, Connolly, Peter, Zhang, Zhuming, Bischoff, James, Rupnow, Brent, Gottardis, Marco, Packman, Kathryn
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Get full text
Journal Article
BCMA, GPRC5D, 및 CD3을 표적화하는 삼중특이적 항체
BRODEUR SCOTT RONALD, GANESAN RAJKUMAR, ATTAR RICARDO MARCOS, PHILIPPAR ULRIKE, YANG DANLIN DAN QING, SINGH SANJAYA, LUISTRO LEOPOLDO, PILLARISETTI KODANDARAM
Year of Publication 19.10.2023
Get full text
Year of Publication 19.10.2023
Patent