Search Results - "LUISELLA TOSCHI" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance

Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance

by Quanz, Maria, Bender, Eckhard, Kopitz, Charlotte, Grünewald, Sylvia, Schlicker, Andreas, Schwede, Wolfgang, Eheim, Ashley, Toschi, Luisella, Neuhaus, Roland, Richter, Carmen, Toedling, Joern, Merz, Claudia, Lesche, Ralf, Kamburov, Atanas, Siebeneicher, Holger, Bauser, Marcus, Hägebarth, Andrea
Published in Molecular cancer therapeutics (01.11.2018)

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Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo

Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo

by Pusch, Stefan, Krausert, Sonja, Fischer, Viktoria, Balss, Jörg, Ott, Martina, Schrimpf, Daniel, Capper, David, Sahm, Felix, Eisel, Jessica, Beck, Ann-Christin, Jugold, Manfred, Eichwald, Viktoria, Kaulfuss, Stefan, Panknin, Olaf, Rehwinkel, Hartmut, Zimmermann, Katja, Hillig, Roman C., Guenther, Judith, Toschi, Luisella, Neuhaus, Roland, Haegebart, Andrea, Hess-Stumpp, Holger, Bauser, Markus, Wick, Wolfgang, Unterberg, Andreas, Herold-Mende, Christel, Platten, Michael, von Deimling, Andreas
Published in Acta neuropathologica (01.04.2017)

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LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain

LRRK1 protein kinase activity is stimulated upon binding of GTP to its Roc domain

by Korr, Daniel, Toschi, Luisella, Donner, Peter, Pohlenz, Hans-Dieter, Kreft, Bertolt, Weiss, Bertram
Published in Cellular signalling (01.06.2006)

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Effect of oncogene activating mutations and kinase inhibitors on amino acid metabolism of human isogenic breast cancer cells

Effect of oncogene activating mutations and kinase inhibitors on amino acid metabolism of human isogenic breast cancer cells

by Kim, Eung-Sam, Samanta, Animesh, Cheng, Hui Shan, Ding, Zhaobing, Han, Weiping, Toschi, Luisella, Chang, Young Tae
Published in Molecular bioSystems (01.01.2015)

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Specific PET Imaging of xC― Transporter Activity Using a 18F-Labeled Glutamate Derivative Reveals a Dominant Pathway in Tumor Metabolism

Specific PET Imaging of xC― Transporter Activity Using a 18F-Labeled Glutamate Derivative Reveals a Dominant Pathway in Tumor Metabolism

by KOGLIN, Norman, MUELLER, Andre, BERNDT, Mathias, SCHMITT-WILLICH, Heribert, TOSCHI, Luisella, STEPHENS, Andrew W, GEKELER, Volker, FRIEBE, Matthias, DINKELBORG, Ludger M
Published in Clinical cancer research (15.09.2011)

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Structural Features Mediating Fibrin Selectivity of Vampire Bat Plasminogen Activators (∗)

Structural Features Mediating Fibrin Selectivity of Vampire Bat Plasminogen Activators (∗)

by Bringmann, Peter, Gruber, Daniel, Liese, Alexandra, Toschi, Luisella, Krätzschmar, Jörn, Schleuning, Wolf-Dieter, Donner, Peter
Published in The Journal of biological chemistry (27.10.1995)

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Abstract 3790: Targeting the one-carbon metabolism protein MTHFD2 for cancer therapy: Exploiting the unique redox status of cancer cells

Abstract 3790: Targeting the one-carbon metabolism protein MTHFD2 for cancer therapy: Exploiting the unique redox status of cancer cells

by Glasauer, Andrea, Steckel, Michael, Haegebarth, Andrea, Bauser, Marcus, Toschi, Luisella
Published in Cancer research (Chicago, Ill.) (15.07.2016)

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Abstract 4460: Targeting the redox-protective protein MTH1 for cancer therapy: A novel way to exploit the unique redox status of cancer cells

Abstract 4460: Targeting the redox-protective protein MTH1 for cancer therapy: A novel way to exploit the unique redox status of cancer cells

by Glasauer, Andrea, Irlbacher, Horst, Richter, Anja, Toschi, Luisella, Steckel, Michael, Haegebarth, Andrea
Published in Cancer research (Chicago, Ill.) (01.08.2015)

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Abstract 4746: Pharmacological characterization of BAY-876, a novel highly selective inhibitor of glucose transporter (GLUT)-1 in vitro and in vivo

Abstract 4746: Pharmacological characterization of BAY-876, a novel highly selective inhibitor of glucose transporter (GLUT)-1 in vitro and in vivo

by Kopitz, Charlotte, Toschi, Luisella, Algire, Carolyn, Héroult, Mélanie, Frisk, Anna-Lena, Meyer, Kirstin, Schmitz, Arndt, Lagkadinou, Eleni, Petrul, Heike, Heisler, Iring, Neuhaus, Roland, Buchmann, Bernd, Himmel, Herbert, Bauser, Marcus, Haegebarth, Andrea, Ziegelbauer, Karl
Published in Cancer research (Chicago, Ill.) (15.07.2016)

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Isogenic human mammary epithelial cell lines: novel tools for target identification and validation: Comprehensive characterization of an isogenic human mammary epithelial cell model provides evidence for epithelial–mesenchymal transition

Isogenic human mammary epithelial cell lines: novel tools for target identification and validation: Comprehensive characterization of an isogenic human mammary epithelial cell model provides evidence for epithelial–mesenchymal transition

by Ulbricht, Ulrike, Sommer, Anette, Beckmann, Georg, Lutzenberger, Manuel, Seidel, Henrik, Kreft, Bertolt, Toschi, Luisella
Published in Breast cancer research and treatment (01.04.2013)

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Effect of oncogene activating mutations and kinase inhibitors on amino acid metabolism of human isogenic breast cancer cellsElectronic supplementary information (ESI) available. See DOI: 10.1039/c5mb00525f

Effect of oncogene activating mutations and kinase inhibitors on amino acid metabolism of human isogenic breast cancer cellsElectronic supplementary information (ESI) available. See DOI: 10.1039/c5mb00525f

by Kim, Eung-Sam, Samanta, Animesh, Cheng, Hui Shan, Ding, Zhaobing, Han, Weiping, Toschi, Luisella, Chang, Young Tae
Year of Publication 10.11.2015

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Pan-Mutant-IDH1 Inhibitor Bay-1436032 Is Highly Effective Against Human IDH1 Mutant Acute Myeloid Leukemia In Vivo

Pan-Mutant-IDH1 Inhibitor Bay-1436032 Is Highly Effective Against Human IDH1 Mutant Acute Myeloid Leukemia In Vivo

by Heuser, Michael, Herbst, Lena, Pusch, Stefan, Klett, Lara, Goparaju, Ramya, Stichel, Damian, Kaulfuss, Stefan, Panknin, Olaf, Zimmermann, Katja, Toschi, Luisella, Neuhaus, Roland, Haegebarth, Andrea, Rehwinkel, Hartmut, Hess-Stumpp, Holger, Bauser, Markus, Bochtler, Tilmann, Struys, Eduard A, Sharma, Amit, Abdellatif, Abdellatif, Geffers, Robert, Araujo Cruz, Michelle M, Thol, Felicitas, Gabdoulline, Razif, Ganser, Arnold, Ho, Anthony D, von Deimling, Andreas, Rippe, Karsten, Chaturvedi, Anuhar, Kraemer, Alwin
Published in Blood (02.12.2016)

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Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets

Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets

by Swanton, Charles, Larkin, James M, Gerlinger, Marco, Eklund, Aron C, Howell, Michael, Stamp, Gordon, Downward, Julian, Gore, Martin, Futreal, P Andrew, Escudier, Bernard, Andre, Fabrice, Albiges, Laurence, Beuselinck, Benoit, Oudard, Stephane, Hoffmann, Jens, Gyorffy, Balázs, Torrance, Chris J, Boehme, Karen A, Volkmer, Hansjuergen, Toschi, Luisella, Nicke, Barbara, Beck, Marlene, Szallasi, Zoltan
Published in Genome medicine (11.08.2010)

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Journal Article

Changes in Cyclin/Proliferating Cell Nuclear Antigen Distribution during DNA Repair Synthesis

Changes in Cyclin/Proliferating Cell Nuclear Antigen Distribution during DNA Repair Synthesis

by Toschi, Luisella, Bravo, Rodrigo
Published in The Journal of cell biology (01.11.1988)

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Journal Article

Cover Picture: Protein-Structure-Based Prediction of Animal Model Suitability for Pharmacodynamic Studies of Subtype-Selective Estrogens (ChemMedChem 11/2006)

Cover Picture: Protein-Structure-Based Prediction of Animal Model Suitability for Pharmacodynamic Studies of Subtype-Selective Estrogens (ChemMedChem 11/2006)

by Toschi, Luisella, Hilbig, Jochen, Wintermantel, Tim, Engelhaupt, Adelheid, Walter, Alexander, Fritzemeier, Karl-Heinrich, Hillisch, Alexander
Published in ChemMedChem (13.11.2006)

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Journal Article

Protein-Structure-Based Prediction of Animal Model Suitability for Pharmacodynamic Studies of Subtype-Selective Estrogens

Protein-Structure-Based Prediction of Animal Model Suitability for Pharmacodynamic Studies of Subtype-Selective Estrogens

by Toschi, Luisella, Hilbig, Jochen, Wintermantel, Tim, Engelhaupt, Adelheid, Walter, Alexander, Fritzemeier, Karl-Heinrich, Hillisch, Alexander
Published in ChemMedChem (01.11.2006)

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Journal Article

2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS

2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS

by ALBUS, UDO, ROSENSTEIN, BJORN, MEIER, HEINRICH, DELBECK, MARTINA, GEHRING, DORIS, MOSIG, JOHANNA, MULLER, THOMAS, LUSTIG, KLEMENS, TOSCHI, LUISELLA, HAHN, MICHAEL
Year of Publication 17.10.2023

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Patent

2-phenyl-3-(piperazinomethyl)imidazo[1,2-A]pyridine derivatives as blockers of task-1 and task-2 channels, for the treatment of sleep-related breathing disorders

2-phenyl-3-(piperazinomethyl)imidazo[1,2-A]pyridine derivatives as blockers of task-1 and task-2 channels, for the treatment of sleep-related breathing disorders

by Mosig, Johanna, Gehring, Doris, Meier, Heinrich, Rosenstein, Björn, Albus, Udo, Lustig, Klemens, Müller, Thomas, Delbeck, Martina, Hahn, Michael, Toschi, Luisella
Year of Publication 01.09.2020

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Patent

2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF THE TASK-1 AND TASK-2 CHANNELS FOR TREATING SLEEP-RELATED BREATHING DISORDERS

2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF THE TASK-1 AND TASK-2 CHANNELS FOR TREATING SLEEP-RELATED BREATHING DISORDERS

by GEHRING, Doris, MÜLLER, Thomas, LUSTIG, Klemens, TOSCHI, Luisella, ALBUS, Udo, HAHN, Michael, MEIER, Heinrich, DELBECK, Martina, ROSENSTEIN, Björn, MOSIG, Johanna
Year of Publication 29.07.2020

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Patent

2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS

2-PHENYL-3-(PIPERAZINOMETHYL)IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS BLOCKERS OF TASK-1 AND TASK-2 CHANNELS, FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS

by GEHRING, Doris, MÜLLER, Thomas, LUSTIG, Klemens, ALBUS, Udo, TOSCHI, Luisella, HAHN, Michael, MEIER, Heinrich, DELBECK, Martina, ROSENSTEIN, Björn, MOSIG, Johanna
Year of Publication 04.10.2019

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Patent

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